Consequences of lack of beta 1 integrin gene expression in mice.

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Genomic sequencing.

1984 • 8,343 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

1993 • 2,370 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

1994 • 1,396 citations

Anchorage dependence, integrins, and apoptosis

1994 • 1,016 citations

Cell adhesion events mediated by α4 integrins are essential in placental and cardiac development

1995 • 792 citations

Embryonic mesodermal defects in α5 integrin-deficient mice

1993 • 694 citations

A potential fusion peptide and an integrin ligand domain in a protein active in sperm–egg fusion

1992 • 680 citations

Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality.

1995 • 593 citations

Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice

1995 • 554 citations

Mouse egg integrin α6β1functions as a sperm receptor

1995 • 472 citations

Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling

1993 • 447 citations

Occupation of the extracellular matrix receptor, integrin, is a control point for myogenic differentiation

1987 • 419 citations

Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis

1992 • 404 citations

Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation.

1995 • 393 citations

Developmental regulation of integrin expression at the time of implantation in the mouse embryo

1993 • 321 citations

An antibody to a receptor for fibronectin and laminin perturbs cranial neural crest development in vivo

1986 • 304 citations

Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease.

1994 • 297 citations

Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts.

1995 • 254 citations

Extracellular matrix 5: Adhesive interactions in early mammalian embryogenesis, implantation, and placentation

1993 • 196 citations

Fibronectin and laminin promote in vitro attachment and outgrowth of mouse blastocysts

1986 • 192 citations

In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells.

1987 • 187 citations

Cell Migration in the Vertebrate Embryo: Role of Cell Adhesion and Tissue Environment in Pattern Formation

1985 • 174 citations

Expression and function of cell surface extracellular matrix receptors in mouse blastocyst attachment and outgrowth.

1988 • 150 citations

Heparan Sulfate Proteoglycan (Perlecan) Expression by Mouse Embryos during Acquisition of Attachment Competence

1993 • 134 citations

Antibodies to β₁‐integrins cause alterations of aortic vasculogenesis, in vivo

1992 • 126 citations

The 140-kDa fibronectin receptor complex is required for mesodermal cell adhesion during gastrulation in the amphibian Pleurodeles waltlii

1988 • 110 citations

The survival of early chick sympathetic neurons in vitro is dependent on a suitable substrate but independent of NGF

1989 • 103 citations

Myoblast migration specifically inhibited in the chick embryo by grafted CSAT hybridoma cells secreting an anti-integrin antibody

1988 • 96 citations

Cell surface glycoproteins mediate compaction, trophoblast attachment, and endoderm formation during early mouse development

1985 • 79 citations

Adhesion and matrix in vertebrate development

1994 • 69 citations

Ontogeny of hyaluronan secretion during early mouse development

1993 • 60 citations

Integrin-type fibronectin receptors of rat arterial smooth muscle cells: isolation, partial characterization and role in cytoskeletal organization and control of differentiated properties

1989 • 52 citations

Perturbation of β1 integrin-mediated adhesions results in altered somite cell shape and behavior

1992 • 52 citations

Probing immune functions in RAG-deficient mice

1994 • 51 citations

Growth cone migration across extracellular matrix components depends on integrin, but migration across glioma cells does not

1988 • 39 citations

Proteoglycan synthesis and metabolism by mouse uterine stroma cultured in vitro

1991 • 26 citations

Carbohydrate antigen expression in murine embryonic stem cells and embryos. I. Lacto and neo-lacto determinants

1993 • 20 citations