Absence of integrin α6 leads to epidermolysis bullosa and neonatal death in mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes

1991 • 771 citations

Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments.

1991 • 755 citations

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line

1982 • 727 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.

1991 • 574 citations

Revised clinical and laboratory criteria for subtypes of inherited epidermolysis bullosa

1991 • 511 citations

Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes.

1990 • 486 citations

Gene targeting of BPAG1: Abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration

1995 • 440 citations

Epithelial detachment due to absence of hemidesmosomes in integrin β4 null mice

1996 • 402 citations

Two rhombomeres are altered in Hoxa-1 mutant mice

1993 • 391 citations

Integrin β4 mutations associated with junctional epidermolysis bullosa with pyloric atresia

1995 • 389 citations

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

1995 • 372 citations

The anchoring filament protein kalinin is synthesized and secreted as a high molecular weight precursor.

1992 • 345 citations

Herlitz's junctional epidermolysis bullosa is linked to mutations in the gene (LAMC2) for the γ2 subunit of nicein/kalinin (LAMININ–5)

1994 • 339 citations

A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody.

1987 • 334 citations

Developmental regulation of integrin expression at the time of implantation in the mouse embryo

1993 • 321 citations

Mutations in the γ2 chain gene (LAMC2) of kalinin/laminin 5 in the junctional forms of epidermolysis bullosa

1994 • 309 citations

Association of the VLA a Subunit with a Novel Protein

1989 • 285 citations

Recognition of the laminin E8 cell-binding site by an integrin possessing the alpha 6 subunit is essential for epithelial polarization in developing kidney tubules.

1990 • 243 citations

A Homozygous Nonsense Mutation in the β3 Chain Gene of Laminin 5 (LAMB3) in Herlitz Junctional Epidermolysis Bullosa

1994 • 229 citations

A function for the integrin alpha 6 beta 4 in the hemidesmosome.

1991 • 225 citations

The α6β1 (VLA-6) and α6β4 protein complexes: tissue distribution and biochemical properties

1990 • 219 citations

Extracellular matrix 5: Adhesive interactions in early mammalian embryogenesis, implantation, and placentation

1993 • 196 citations

Monoclonal antibody GB3, a new probe for the study of human basement membranes and hemidesmosomes

1987 • 185 citations

The beta 4 subunit cytoplasmic domain mediates the interaction of alpha 6 beta 4 integrin with the cytoskeleton of hemidesmosomes.

1993 • 124 citations

Differential expression of laminin isoforms and α6‐β4 integrin subunits in the developing human and mouse intestine

1994 • 116 citations

Adhesion Receptors as Therapeutic Targets

1995 • 112 citations

Variants of the α₆β₁Laminin Receptor in Early Murine Development: Distribution, Molecular Cloning and Chromosomal Localization of the Mouse Integrin α₆Subunit

1993 • 108 citations

Function and spatial distribution in developing chick retina of the laminin receptor α6β1 and its isoforms

1993 • 100 citations

Expression patterns of laminin receptor splice variants α6Aβ1 and α6Bβ1 suggest different roles in mouse development

1995 • 57 citations

Tumor antigen on benign adenomas and on murine lung carcinomas quantitated by a two-site monoclonal antibody assay.

1986 • 40 citations

Gradient of Integrin α6A Distribution in the Myocardium During Early Heart Development

1995 • 32 citations