TGF‐β control of cell proliferation

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

Smad-dependent and Smad-independent pathways in TGF-β family signalling

2003 • 5,052 citations

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

TGF-β signaling in tumor suppression and cancer progression

2001 • 2,235 citations

Cellular Actions of the Insulin-Like Growth Factor Binding Proteins

2002 • 1,717 citations

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

2003 • 1,115 citations

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

2005 • 852 citations

Insulin Action and the Insulin Signaling Network*

1995 • 823 citations

Physiological Actions and Clinical Applications of Transforming Growth Factor-β (TGF-β)

1993 • 755 citations

Caveolin-1 Regulates Transforming Growth Factor (TGF)-β/SMAD Signaling through an Interaction with the TGF-β Type I Receptor

2001 • 638 citations

Mechanisms of TGF-β signaling in regulation of cell growth and differentiation

2002 • 521 citations

Lipoprotein Receptors in the Nervous System

2002 • 441 citations

Role of Ras and Mapks in TGFβ signaling

2000 • 430 citations

Molecular and Cell Biology of TGF-β

1998 • 379 citations

Cross‐talk between ERK MAP kinase and Smad‐signaling pathways enhances TGF‐β dependent responses in human mesangial cells

2003 • 359 citations

Solar Ultraviolet Irradiation Reduces Collagen in Photoaged Human Skin by Blocking Transforming Growth Factor-β Type II Receptor/Smad Signaling

2004 • 341 citations

Diverse roles for the LDL receptor family

2002 • 311 citations

The Type V Transforming Growth Factor β Receptor Is the Putative Insulin-like Growth Factor-binding Protein 3 Receptor

1997 • 259 citations

Role of Endoglin in Cellular Responses to Transforming Growth Factor-β

1998 • 223 citations

TGF-β inhibits p70 S6 kinase via protein phosphatase 2A to induce G₁ arrest

2000 • 220 citations

Insulin action and the insulin signaling network

1995 • 216 citations

Ligand-dependent and -independent Transforming Growth Factor-β Receptor Recycling Regulated by Clathrin-mediated Endocytosis and Rab11

2004 • 206 citations

Genomic instability in the type II TGF-beta1 receptor gene in atherosclerotic and restenotic vascular cells.

1997 • 171 citations

Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas exotoxin A Evidence that this protein is required for uptake and degradation of multiple ligands

1994 • 167 citations

Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis.

1996 • 161 citations

Cellular growth inhibition by IGFBP‐3 and TGF‐β₁requires LRP‐1

2003 • 154 citations

Frequent Silencing of Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B ) Expression by Genetic and Epigenetic Mechanisms in Esophageal Squamous Cell Carcinoma

2004 • 138 citations

Betaglycan Inhibits TGF-β Signaling by Preventing Type I-Type II Receptor Complex Formation

2002 • 138 citations

Transforming Growth Factor-β Receptors Interact with AP2 by Direct Binding to β2 Subunit

2002 • 127 citations

The Role of Internalization in Transforming Growth Factor β1-induced Smad2 Association with Smad Anchor for Receptor Activation (SARA) and Smad2-dependent Signaling in Human Mesangial Cells

2004 • 124 citations

Reduced Expression of Transforming Growth Factor β Type I Receptor Contributes to the Malignancy of Human Colon Carcinoma Cells

1996 • 122 citations

Interactions of High Affinity Insulin-like Growth Factor-binding Proteins with the Type V Transforming Growth Factor-β Receptor in Mink Lung Epithelial Cells

1999 • 107 citations

Synthetic TGF‐β antagonist accelerates wound healing and reduces scarring

2002 • 98 citations

Suppressor and oncogenic roles of transforming growth factor-β and its signaling pathways in tumorigenesis

2001 • 97 citations

TGF-β in diabetic kidney disease: role of novel signaling pathways

2000 • 96 citations

Insulin-Like Growth Factor I Receptor Signaling and Nuclear Translocation of Insulin Receptor Substrates 1 and 2

2003 • 96 citations

TGF-β receptor expression and binding in rat mesangial cells: Modulation by glucose and cyclic mechanical strain

1999 • 79 citations

α₂‐Macroglobulin and the α₂‐Macroglobulin Receptor/LRP A Growth Regulatory Axisa

1994 • 77 citations

An increased transforming growth factor β receptor type I:Type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase‐deficient transforming growth factor β receptor type II in scleroderma

2004 • 68 citations

Purification of a new type high molecular weight receptor (type V receptor) of transforming growth factor beta (TGF-beta) from bovine liver. Identification of the type V TGF-beta receptor in cultured cells

1991 • 68 citations

Hepatocyte Growth Factor Releases Epithelial and Endothelial Cells from Growth Arrest Induced by Transforming Growth Factor-β1

1996 • 58 citations

LRP‐1/TβR‐V mediates TGF‐β1‐induced growth inhibition in CHO cells

2004 • 57 citations

Mechanisms of TGF-β-Induced Cell Cycle Arrest

1998 • 52 citations

Regulation of transforming growth factor beta 1 action by multiple transducing pathways: evidence for both G protein-dependent and -independent signaling.

1989 • 50 citations

Function of the Type V Transforming Growth Factor β Receptor in Transforming Growth Factor β-induced Growth Inhibition of Mink Lung Epithelial Cells

1997 • 42 citations

Expression of a new type high molecular weight receptor (type V receptor) of transforming growth factor β in normal and transformed cells

1991 • 42 citations

Transforming Growth Factor ॆ Peptide Antagonists and Their Conversion to Partial Agonists

1997 • 39 citations

Identification of insulin receptor substrate proteins as key molecules for the TβR‐V/LRP‐1‐mediated growth inhibitory signaling cascade in epithelial and myeloid cells

2004 • 36 citations

TGF-β receptors: a complicated system of multiple binding proteins

1993 • 32 citations

Insulin Receptor Substrate-1 Is Present in Hepatocyte Nuclei from Intact Rats

2002 • 27 citations

Characterization of transforming growth factor-beta (TGF-beta) receptors on BeWo choriocarcinoma cells including the identification of a novel 38-kDa TGF-beta binding glycoprotein.

1992 • 27 citations

Restored expression of transforming growth factor β type II receptor ink-ras-transformed thyroid cells, TGFβ-resistant, reverts their malignant phenotype

1997 • 26 citations

Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3

2000 • 26 citations

A Rat Pituitary Tumor Cell Line (GH3 ) Expresses Type I and Type II Receptors and Other Cell Surface Binding Protein(s) for Transforming Growth Factor- β

1995 • 22 citations

Cellular growth inhibition by TGF‐β₁ involves IRS proteins

2004 • 18 citations