α₂‐Macroglobulin and the α₂‐Macroglobulin Receptor/LRP A Growth Regulatory Axisa

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

Transforming growth factor production by chemically transformed cells.

1981 • 506 citations

α ₂ “Macroglobulin, a multifunctional binding protein with targeting characteristics

1992 • 454 citations

Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines.

1979 • 230 citations

Cytokine binding and clearance properties of proteinase-activated alpha 2-macroglobulins.

1991 • 216 citations

Functional modifications of alpha 2-macroglobulin by primary amines. I. Characterization of alpha 2 M after derivatization by methylamine and by factor XIII.

1981 • 152 citations

Differential inhibition of transforming growth factor beta 1 and beta 2 activity by alpha 2-macroglobulin.

1990 • 148 citations

An alpha 2-macroglobulin receptor-dependent mechanism for the plasma clearance of transforming growth factor-beta 1 in mice.

1991 • 139 citations

Regulation of macrophage alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein by lipopolysaccharide and interferon-gamma.

1993 • 100 citations

Binding of tumor necrosis factor alpha to activated forms of human plasma alpha 2 macroglobulin.

1991 • 94 citations

A cell cycle and mutational analysis of anchorage-independent growth: cell adhesion and TGF-beta 1 control G1/S transit specifically

1993 • 70 citations

Binding of platelet-derived growth factor-BB and transforming growth factor-β 1 to α2-macroglobulin in vitro and in vivo: comparison of receptor-recognized and non-recognized α2-macroglobulin conformations

1993 • 67 citations

Alpha 2-macroglobulin and serum preferentially counteract the mitoinhibitory effect of transforming growth factor-beta 2 in rat hepatocytes.

1990 • 64 citations

Colony-stimulating factor-1 modulates alpha 2-macroglobulin receptor expression in murine bone marrow macrophages.

1990 • 60 citations

PDGF‐stimulated fibroblast proliferation is enhanced synergistically by receptor‐recognized α₂‐Macroglobulin

1990 • 56 citations

Alpha 2-macroglobulin: a protein at the interface of fibrinolysis and cellular growth regulation.

1992 • 51 citations

Mechanism of insulin incorporation into .alpha.2-macroglobulin: implications for the study of peptide and growth factor binding

1991 • 51 citations

Activated alpha 2-macroglobulin and transforming growth factor-beta 1 induce a synergistic smooth muscle cell proliferative response.

1993 • 50 citations

Kinetics of α₂‐macroglobulin endocytosis and degradation in mutant and wild‐type Chinese hamster ovary cells

1989 • 40 citations

Binding of transforming growth factor-β1 to methylamine-modified α2-macroglobulin and to binary and ternary α2-macroglobulin-proteinase complexes

1992 • 37 citations

Binding of transforming growth factor-β1 to immobilized human α2-macroglobulin

1992 • 24 citations

Epidermal growth factor binding to human .alpha.2-macroglobulin. Implications for .alpha.2-macroglobulin-growth factor interactions

1993 • 21 citations

Electron microscopy studies of α2-Macroglobulin Conformational Intermediates Obtained by Derivatization with -Dichlorodiammineplatinum (II)

1989 • 20 citations

Inhibition of adrenocortical steroidogenesis by α2-macroglobulin is caused by associated transforming growth factor β

1992 • 16 citations