Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

1987 • 1,243 citations

Peptide Growth Factors and Their Receptors

1991 • 1,221 citations

The plasminogen activator/plasmin system.

1991 • 1,196 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

Accelerated Healing of Incisional Wounds in Rats Induced by Transforming Growth Factor-β

1987 • 938 citations

Basic fibroblast growth factor induces angiogenesis in vitro.

1986 • 828 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro

1989 • 746 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Receptors for the TGF-β family

1992 • 638 citations

Capillary endothelial cell cultures: phenotypic modulation by matrix components.

1983 • 611 citations

Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix.

1988 • 571 citations

Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane.

1990 • 470 citations

Tumor-promoting phorbol esters induce angiogenesis in vitro

1985 • 470 citations

Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro.

1990 • 466 citations

How does extracellular matrix control capillary morphogenesis?

1989 • 466 citations

PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.

1994 • 428 citations

Urokinase and urokinase receptor: A paracrine/autocrine system regulating cell migration and invasiveness

1993 • 402 citations

Transforming growth factors and the regulation of cell proliferation

1990 • 390 citations

Inactivation of the Type II Receptor Reveals Two Receptor Pathways for the Diverse TGF-β Activities

1993 • 388 citations

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells.

1987 • 378 citations

Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms

1990 • 342 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

Inhibitory action of transforming growth factor beta on endothelial cells.

1987 • 324 citations

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

1990 • 319 citations

TGF-β-receptor-mediated signaling

1994 • 274 citations

Transforming growth factor-beta induction of type-1 plasminogen activator inhibitor. Pericellular deposition and sensitivity to exogenous urokinase.

1987 • 263 citations

Purification and characterization of heparin-binding endothelial cell growth factors.

1986 • 263 citations

Codistribution of collagen types IV and AB2 in basement membranes and mesangium of the kidney. an immunoferritin study of ultrathin frozen sections.

1980 • 233 citations

Collagen polymorphism in the lungAn immunochemical study of pulmonary fibrosis

1980 • 220 citations

Extracellular Matrix‐Degrading Proteinases in the Nervous System

1994 • 208 citations

Proteolytic balance and capillary morphogenesis

1990 • 203 citations

Regulation of in vitro capillary tube formation by anti-integrin antibodies.

1993 • 194 citations

Transforming growth factor beta₁ modulates extracellular matrix organization and cell‐cell junctional complex formation during in vitro angiogenesis

1990 • 184 citations

Receptors for Transforming Growth Factor-β

1993 • 181 citations

Inhibition of growth by transforming growth factor-beta following fusion of two nonresponsive human carcinoma cell lines. Implication of the type II receptor in growth inhibitory responses.

1992 • 176 citations

Receptors for the TGF-β superfamily: multiple polypeptides and serine/threonine kinases

1993 • 164 citations

Glucocorticoid regulation of transforming growth factor beta 1 activity and binding in osteoblast-enriched cultures from fetal rat bone.

1991 • 163 citations

Binding of Transforming Growth Factor-β to Cell Surface Proteins Varies with Cell Type

1989 • 160 citations

Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1.

1992 • 155 citations

Modulation of transforming growth factor beta receptors of rat lipocytes during the hepatic wound healing response. Enhanced binding and reduced gene expression accompany cellular activation in culture and in vivo.

1994 • 154 citations

Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis.

1994 • 152 citations

Stimulation of normal human fibroblast collagen production and processing by transforming growth factor-β

1986 • 145 citations

Vascular cells respond differentially to transforming growth factors beta 1 and beta 2 in vitro.

1991 • 137 citations

Independent Changes in Type I and Type II Receptors for Transforming Growth Factor β Induced by Bone Morphogenetic Protein 2 Parallel Expression of the Osteoblast Phenotype

1995 • 132 citations

Expression of Transforming Growth Factor Type III Receptor in Vascular Endothelial Cells Increases Their Responsiveness to Transforming Growth Factor β2

1995 • 128 citations

The microvascular extracellular matrix. Developmental changes during angiogenesis in the aortic ring-plasma clot model.

1987 • 118 citations

The Heparin-Binding (Fibroblast) Growth Factor Family Of Proteins

1989 • 106 citations

Effects of soluble factors and extracellular matrix components on vascular cell behavior in vitro and in vivo: Models of de‐endothelialization and repair

1991 • 99 citations

Parathyroid hormone modulates transforming growth factor beta activity and binding in osteoblast-enriched cell cultures from fetal rat parietal bone.

1988 • 98 citations

Isolation of the Oncogene and Epidermal Growth Factor-Induced Transin Gene: Complex Control in Rat Fibroblasts

1986 • 90 citations

Decrease in transforming growth factor-beta binding and action during differentiation in muscle cells.

1988 • 78 citations

Different Signals Mediate Transforming Growth Factor-β1-Induced Growth Inhibition and Extracellular Matrix Production in Prostatic Carcinoma Cells

1993 • 70 citations

Matrix composition, organization and soluble factors: Modulators of microvascular cell differentiation in vitro

1992 • 69 citations

Modulation of vascular cell behavior by transforming growth factors β

1992 • 61 citations

Modulation of actin mRNAs in cultured vascular cells by matrix components and TGF-β1

1989 • 60 citations

Multiple regulatory effects by transforming growth factor-beta on type I collagen levels in osteoblast-enriched cultures from fetal rat bone.

1992 • 57 citations

Urokinase and urokinase receptor: a paracrinelautocrine system regulating cell migration and invasiveness

1993 • 56 citations

Bovine adrenocortical cells exhibit high affinity transforming growth factor-beta receptors which are regulated by adrenocorticotropin.

1988 • 55 citations

Basic FGF Treatment of Endothelial Cells Down-regulates the 85-KDa TGFβ Receptor Subtype and Decreases the Growth Inhibitory Response to TGF-β1

1990 • 48 citations

Functional receptors for transforming growth factor-beta are retained by biochemically differentiated C2 myocytes in growth factor-deficient medium containing EGTA but down-regulated during terminal differentiation.

1990 • 39 citations

Glucocorticoid Regulation of Transforming Growth Factor β1 Activity and Binding in Osteoblast-Enriched Cultures from Fetal Rat Bone

1991 • 14 citations