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Cellular growth inhibition by IGFBP‐3 and TGF‐β1requires LRP‐1

Data up to Jan 2025

Published2003
Citations154
References53

Total Citations Per Year

Abstract

References (53)

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

TGF-β signaling in tumor suppression and cancer progression

2001 • 2,235 citations

STRUCTURES AND FUNCTIONS OF MULTILIGAND LIPOPROTEIN RECEPTORS: Macrophage Scavenger Receptors and LDL Receptor-Related Protein (LRP)

1994 • 1,175 citations

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.

1988 • 947 citations

The Transforming Growth Factor-βs

1991 • 882 citations

LRP: a multifunctional scavenger and signaling receptor

2001 • 856 citations

TGF-β signaling: positive and negative effects on tumorigenesis

2002 • 830 citations

The Transforming Growth Factor-βs

1990 • 741 citations

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.

1990 • 666 citations

Receptors for the TGF-β family

1992 • 638 citations

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

1991 • 586 citations

Mechanisms of TGF-β signaling in regulation of cell growth and differentiation

2002 • 521 citations

Molecular and Cell Biology of TGF-β

1998 • 379 citations

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

1990 • 319 citations

Diverse roles for the LDL receptor family

2002 • 311 citations

104 candidate genes for the hypoxic tumor phenotype

1999 • 283 citations

The Type V Transforming Growth Factor β Receptor Is the Putative Insulin-like Growth Factor-binding Protein 3 Receptor

1997 • 259 citations

Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines.

1979 • 230 citations

TGF-β inhibits p70 S6 kinase via protein phosphatase 2A to induce G1 arrest

2000 • 220 citations

Human transforming growth factor beta.alpha 2-macroglobulin complex is a latent form of transforming growth factor beta.

1988 • 209 citations

Internalization-Dependent and -Independent Requirements for Transforming Growth Factor β Receptor Signaling via the Smad Pathway

2002 • 187 citations

A Novel Mechanism for Regulating Transforming Growth Factor β (TGF-β) Signaling

2001 • 186 citations

Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas exotoxin A Evidence that this protein is required for uptake and degradation of multiple ligands

1994 • 167 citations

Cyclin-Dependent Kinase Regulation during G1 Phase and Cell Cycle Regulation by TGF-ß

1997 • 147 citations

Functional Roles for the Cytoplasmic Domain of the Type III Transforming Growth Factor β Receptor in Regulating Transforming Growth Factor β Signaling

2001 • 139 citations

Betaglycan Inhibits TGF-β Signaling by Preventing Type I-Type II Receptor Complex Formation

2002 • 138 citations

Reduced Expression of Transforming Growth Factor β Type I Receptor Contributes to the Malignancy of Human Colon Carcinoma Cells

1996 • 122 citations

LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines.

2000 • 111 citations

Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein [published erratum appears in J Cell Biol 1995 Aug;130(4):1015]

1995 • 110 citations

Interactions of High Affinity Insulin-like Growth Factor-binding Proteins with the Type V Transforming Growth Factor-β Receptor in Mink Lung Epithelial Cells

1999 • 107 citations

Increased expression of low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor in human malignant astrocytomas.

1997 • 103 citations

The LDL receptor gene family: signaling functions during development

2001 • 79 citations

Receptor‐associated protein: a specialized chaperone and antagonist for members of the LDL receptor gene family

1998 • 77 citations

α2‐Macroglobulin and the α2‐Macroglobulin Receptor/LRP A Growth Regulatory Axisa

1994 • 77 citations

Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line.

2001 • 72 citations

Purification of a new type high molecular weight receptor (type V receptor) of transforming growth factor beta (TGF-beta) from bovine liver. Identification of the type V TGF-beta receptor in cultured cells

1991 • 68 citations

Signaling by the transforming growth factor-β receptor

1995 • 67 citations

GH3 Pituitary Tumor Cells Contain Heteromeric Type I and Type II Receptor Complexes for Transforming Growth Factor β and Activin-A

1995 • 64 citations

Evidence of Functional Modulation of the MEKK/JNK/cJun Signaling Cascade by the Low Density Lipoprotein Receptor-related Protein (LRP)

2002 • 59 citations

Hepatocyte Growth Factor Releases Epithelial and Endothelial Cells from Growth Arrest Induced by Transforming Growth Factor-β1

1996 • 58 citations

Mechanisms of TGF-β-Induced Cell Cycle Arrest

1998 • 52 citations

Transforming growth factor beta (TGF-beta) type V receptor has a TGF-beta-stimulated serine/threonine-specific autophosphorylation activity.

1992 • 48 citations

Expression of a new type high molecular weight receptor (type V receptor) of transforming growth factor β in normal and transformed cells

1991 • 42 citations

Function of the Type V Transforming Growth Factor β Receptor in Transforming Growth Factor β-induced Growth Inhibition of Mink Lung Epithelial Cells

1997 • 42 citations

Transforming Growth Factor ॆ Peptide Antagonists and Their Conversion to Partial Agonists

1997 • 39 citations

Lack of responsiveness to TGF-β1 in a thyroid carcinoma cell line with functional type I and type II TGF-β receptors and Smad proteins, suggests a novel mechanism for TGF-β insensitivity in carcinoma cells

1999 • 30 citations

Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3

2000 • 26 citations

Expression of α2-macroglobulin receptor/low density lipoprotein receptor-related protein on surfaces of tumour ceils: a study using flow cytometry

1997 • 24 citations

A Rat Pituitary Tumor Cell Line (GH3 ) Expresses Type I and Type II Receptors and Other Cell Surface Binding Protein(s) for Transforming Growth Factor- β

1995 • 22 citations

Cell Surface Retention Sequence Binding Protein-1 Interacts with the v-sis Gene Product and Platelet-derived Growth Factor β-Type Receptor in Simian Sarcoma Virus-transformed Cells

1999 • 14 citations

Blockade of the α2‐Macroglobulin Receptor/Low‐Density‐Lipoprotein‐Receptor‐Related Protein on Rat Liver Parenchymal Cells by the 39‐kDa Receptor‐Associated Protein Leaves the Interaction of β‐Migrating very‐Low‐Density Lipoprotein with the Lipoprotein Remnant Receptor Unaffected

1996 • 12 citations

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Cellular growth inhibition by IGFBP‐3 and TGF‐β1requires LRP‐1 (2003) – The FASEB Journal | Metascience Observatory Explorer