Cellular growth inhibition by IGFBP‐3 and TGF‐β1requires LRP‐1
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References (53)
TGF-β SIGNAL TRANSDUCTION
1998 • 7,582 citations
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 • 3,650 citations
The Transforming Growth Factor-beta Family
1990 • 3,028 citations
TGF-β signaling in tumor suppression and cancer progression
2001 • 2,235 citations
STRUCTURES AND FUNCTIONS OF MULTILIGAND LIPOPROTEIN RECEPTORS: Macrophage Scavenger Receptors and LDL Receptor-Related Protein (LRP)
1994 • 1,175 citations
Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.
1988 • 947 citations
The Transforming Growth Factor-βs
1991 • 882 citations
LRP: a multifunctional scavenger and signaling receptor
2001 • 856 citations
TGF-β signaling: positive and negative effects on tumorigenesis
2002 • 830 citations
The Transforming Growth Factor-βs
1990 • 741 citations
Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.
1990 • 666 citations
Receptors for the TGF-β family
1992 • 638 citations
39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.
1991 • 586 citations
Mechanisms of TGF-β signaling in regulation of cell growth and differentiation
2002 • 521 citations
Molecular and Cell Biology of TGF-β
1998 • 379 citations
Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.
1990 • 319 citations
Diverse roles for the LDL receptor family
2002 • 311 citations
104 candidate genes for the hypoxic tumor phenotype
1999 • 283 citations
The Type V Transforming Growth Factor β Receptor Is the Putative Insulin-like Growth Factor-binding Protein 3 Receptor
1997 • 259 citations
Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines.
1979 • 230 citations
TGF-β inhibits p70 S6 kinase via protein phosphatase 2A to induce G1 arrest
2000 • 220 citations
Human transforming growth factor beta.alpha 2-macroglobulin complex is a latent form of transforming growth factor beta.
1988 • 209 citations
Internalization-Dependent and -Independent Requirements for Transforming Growth Factor β Receptor Signaling via the Smad Pathway
2002 • 187 citations
A Novel Mechanism for Regulating Transforming Growth Factor β (TGF-β) Signaling
2001 • 186 citations
Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas exotoxin A Evidence that this protein is required for uptake and degradation of multiple ligands
1994 • 167 citations
Cyclin-Dependent Kinase Regulation during G1 Phase and Cell Cycle Regulation by TGF-ß
1997 • 147 citations
Functional Roles for the Cytoplasmic Domain of the Type III Transforming Growth Factor β Receptor in Regulating Transforming Growth Factor β Signaling
2001 • 139 citations
Betaglycan Inhibits TGF-β Signaling by Preventing Type I-Type II Receptor Complex Formation
2002 • 138 citations
Reduced Expression of Transforming Growth Factor β Type I Receptor Contributes to the Malignancy of Human Colon Carcinoma Cells
1996 • 122 citations
LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines.
2000 • 111 citations
Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein [published erratum appears in J Cell Biol 1995 Aug;130(4):1015]
1995 • 110 citations
Interactions of High Affinity Insulin-like Growth Factor-binding Proteins with the Type V Transforming Growth Factor-β Receptor in Mink Lung Epithelial Cells
1999 • 107 citations
Increased expression of low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor in human malignant astrocytomas.
1997 • 103 citations
The LDL receptor gene family: signaling functions during development
2001 • 79 citations
Receptor‐associated protein: a specialized chaperone and antagonist for members of the LDL receptor gene family
1998 • 77 citations
α2‐Macroglobulin and the α2‐Macroglobulin Receptor/LRP A Growth Regulatory Axisa
1994 • 77 citations
Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line.
2001 • 72 citations
Purification of a new type high molecular weight receptor (type V receptor) of transforming growth factor beta (TGF-beta) from bovine liver. Identification of the type V TGF-beta receptor in cultured cells
1991 • 68 citations
Signaling by the transforming growth factor-β receptor
1995 • 67 citations
GH3 Pituitary Tumor Cells Contain Heteromeric Type I and Type II Receptor Complexes for Transforming Growth Factor β and Activin-A
1995 • 64 citations
Evidence of Functional Modulation of the MEKK/JNK/cJun Signaling Cascade by the Low Density Lipoprotein Receptor-related Protein (LRP)
2002 • 59 citations
Hepatocyte Growth Factor Releases Epithelial and Endothelial Cells from Growth Arrest Induced by Transforming Growth Factor-β1
1996 • 58 citations
Mechanisms of TGF-β-Induced Cell Cycle Arrest
1998 • 52 citations
Transforming growth factor beta (TGF-beta) type V receptor has a TGF-beta-stimulated serine/threonine-specific autophosphorylation activity.
1992 • 48 citations
Expression of a new type high molecular weight receptor (type V receptor) of transforming growth factor β in normal and transformed cells
1991 • 42 citations
Function of the Type V Transforming Growth Factor β Receptor in Transforming Growth Factor β-induced Growth Inhibition of Mink Lung Epithelial Cells
1997 • 42 citations
Transforming Growth Factor ॆ Peptide Antagonists and Their Conversion to Partial Agonists
1997 • 39 citations
Lack of responsiveness to TGF-β1 in a thyroid carcinoma cell line with functional type I and type II TGF-β receptors and Smad proteins, suggests a novel mechanism for TGF-β insensitivity in carcinoma cells
1999 • 30 citations
Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3
2000 • 26 citations
Expression of α2-macroglobulin receptor/low density lipoprotein receptor-related protein on surfaces of tumour ceils: a study using flow cytometry
1997 • 24 citations
A Rat Pituitary Tumor Cell Line (GH3 ) Expresses Type I and Type II Receptors and Other Cell Surface Binding Protein(s) for Transforming Growth Factor- β
1995 • 22 citations
Cell Surface Retention Sequence Binding Protein-1 Interacts with the v-sis Gene Product and Platelet-derived Growth Factor β-Type Receptor in Simian Sarcoma Virus-transformed Cells
1999 • 14 citations
Blockade of the α2‐Macroglobulin Receptor/Low‐Density‐Lipoprotein‐Receptor‐Related Protein on Rat Liver Parenchymal Cells by the 39‐kDa Receptor‐Associated Protein Leaves the Interaction of β‐Migrating very‐Low‐Density Lipoprotein with the Lipoprotein Remnant Receptor Unaffected
1996 • 12 citations