Deciphering the Phosphorylation “Code” of the Glucocorticoid Receptor in Vivo

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*

1997 • 1,678 citations

Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation.

1996 • 992 citations

Crystal Structure of Glycogen Synthase Kinase 3β

2001 • 636 citations

A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing

1988 • 485 citations

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1987 • 428 citations

Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product

1985 • 368 citations

Activation of Estrogen Receptor α by S118 Phosphorylation Involves a Ligand-Dependent Interaction with TFIIH and Participation of CDK7

2000 • 286 citations

Mitogen-Activated and Cyclin-Dependent Protein Kinases Selectively and Differentially Modulate Transcriptional Enhancement by the Glucocorticoid Receptor

1997 • 271 citations

Glucocorticoid Receptor-Mediated Cell Cycle Arrest Is Achieved through Distinct Cell-Specific Transcriptional Regulatory Mechanisms

1997 • 266 citations

Protein Phosphatase 5 Is a Major Component of Glucocorticoid Receptor·hsp90 Complexes with Properties of an FK506-binding Immunophilin

1997 • 264 citations

Mouse Glucocorticoid Receptor Phosphorylation Status Influences Multiple Functions of the Receptor Protein

1997 • 263 citations

Identification of phosphorylated sites in the mouse glucocorticoid receptor.

1991 • 208 citations

The Function of Steroid Hormone Receptors Is Inhibited by the hsp90-specific Compound Geldanamycin

1997 • 162 citations

Protein Phosphatase Types 1 and/or 2A Regulate Nucleocytoplasmic Shuttling of Glucocorticoid Receptors

1991 • 153 citations

Novel glucocorticoid receptor coactivator effector mechanisms

2001 • 149 citations

Ser/Thr Protein Phosphatase Type 5 (PP5) Is a Negative Regulator of Glucocorticoid Receptor-Mediated Growth Arrest

1999 • 126 citations

Three Amino Acid Substitutions Selectively Disrupt the Activation but Not the Repression Function of the Glucocorticoid Receptor N Terminus

1997 • 116 citations

Differential Hormone-Dependent Phosphorylation of Progesterone Receptor A and B Forms Revealed by a Phosphoserine Site-Specific Monoclonal Antibody

2000 • 109 citations

Role of Acidic and Phosphorylated Residues in Gene Activation by the Glucocorticoid Receptor

1995 • 107 citations

Intragenic sequences of the human glucocorticoid receptor complementary DNA mediate hormone-inducible receptor messenger RNA down-regulation through multiple mechanisms.

1994 • 101 citations

Protracted Nuclear Export of Glucocorticoid Receptor Limits Its Turnover and Does Not Require the Exportin 1/CRM1-Directed Nuclear Export Pathway

2000 • 99 citations

Site-directed mutagenesis of the phosphorylation sites in the mouse glucocorticoid receptor.

1993 • 96 citations

Das SAPHO-Syndrom: Klinisch-rheumatologische und radiologische Differenzierung und Klassifizierung eines Krankengutes von 86 Fällen

2000 • 91 citations

Nuclear localization of vertebrate cyclin a correlates with its ability to form complexes with cdk catalytic subunits

1993 • 90 citations

Molecular Biology of Steroid and Nuclear Hormone Receptors

1998 • 79 citations

Kinetics of glucocorticoid receptor phosphorylation in intact cells. Evidence for hormone-induced hyperphosphorylation after activation and recycling of hyperphosphorylated receptors.

1993 • 71 citations

Effects of okadaic acid, a protein phosphatase inhibitor, on glucocorticoid receptor-mediated enhancement.

1992 • 64 citations

Molecular genetic dissection of glucocorticoid receptor function in vivo

2000 • 48 citations

Glucocorticoid receptors: ATP-dependent cycling and hormone-dependent hyperphosphorylation

1993 • 32 citations

Molecular biology of steroid and nuclear hormone receptors

1999 • 21 citations

Using yeast to study glucocorticoid receptor phosphorylation

1998 • 16 citations

Regulation of Glucocorticoid and Estrogen Receptor Activity by Phosphorylation

1998 • 5 citations