Differential Hormone-Dependent Phosphorylation of Progesterone Receptor A and B Forms Revealed by a Phosphoserine Site-Specific Monoclonal Antibody

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock

1993 • 817 citations

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

1993 • 749 citations

Phosphorylation of the human estrogen receptor. Identification of hormone-regulated sites and examination of their influence on transcriptional activity.

1994 • 460 citations

Ligand-Independent Recruitment of SRC-1 to Estrogen Receptor β through Phosphorylation of Activation Function AF-1

1999 • 460 citations

Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.

1993 • 451 citations

Steroid hormone receptors and their regulation by phosphorylation

1996 • 361 citations

The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells.

1994 • 343 citations

High-Mobility Group Chromatin Proteins 1 and 2 Functionally Interact with Steroid Hormone Receptors To Enhance Their DNA Binding In Vitro and Transcriptional Activity in Mammalian Cells

1998 • 338 citations

Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors.

1993 • 330 citations

Role of the Jun Kinase Pathway in the Regulation of c-Jun Expression and Apoptosis in Sympathetic Neurons

1998 • 284 citations

Mitogen-Activated and Cyclin-Dependent Protein Kinases Selectively and Differentially Modulate Transcriptional Enhancement by the Glucocorticoid Receptor

1997 • 271 citations

Mouse Glucocorticoid Receptor Phosphorylation Status Influences Multiple Functions of the Receptor Protein

1997 • 263 citations

Ligand-Modulated Regulation of Progesterone Receptor Messenger Ribonucleic Acid and Protein in Human Breast Cancer Cell Lines

1988 • 214 citations

New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP.

1994 • 214 citations

The progesterone antagonist RU486 acquires agonist activity upon stimulation of cAMP signaling pathways.

1993 • 208 citations

Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases

1997 • 202 citations

Mapping and Characterization of the Functional Domains Responsible for the Differential Activity of the A and B Isoforms of the Human Progesterone Receptor

1997 • 187 citations

Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP

1993 • 181 citations

Protein Phosphatase Types 1 and/or 2A Regulate Nucleocytoplasmic Shuttling of Glucocorticoid Receptors

1991 • 153 citations

Differential Localization and Activity of the A- and B-Forms of the Human Progesterone Receptor Using Green Fluorescent Protein Chimeras

1999 • 149 citations

An N-terminal Inhibitory Function, IF, Suppresses Transcription by the A-isoform but Not the B-isoform of Human Progesterone Receptors

1998 • 145 citations

Human Progesterone Receptor Complexed with the Antagonist RU 486 Binds to Hormone Response Elements in a Structurally Altered Form

1989 • 138 citations

Effects of hormone and cellular modulators of protein phosphorylation on transcriptional activity, DNA binding, and phosphorylation of human progesterone receptors.

1992 • 117 citations

Site-directed mutagenesis of the phosphorylation sites in the mouse glucocorticoid receptor.

1993 • 96 citations

Phosphorylation of Human Progesterone Receptor by Cyclin-Dependent Kinase 2 on Three Sites That Are Authentic Basal Phosphorylation SitesIn Vivo

1997 • 94 citations

A New Monoclonal Antibody Which Selectively Recognizes the Active Form of Src Tyrosine Kinase

1996 • 87 citations

Efficient selection of recombinant adenoviruses by vectors that express beta-galactosidase

1995 • 84 citations

Ligands induce conformational changes in the carboxyl-terminus of progesterone receptors which are detected by a site-directed antipeptide monoclonal antibody.

1992 • 81 citations

Identification of phosphorylation sites unique to the B form of human progesterone receptor. In vitro phosphorylation by casein kinase II.

1994 • 80 citations

Identification of a group of Ser-Pro motif hormone-inducible phosphorylation sites in the human progesterone receptor.

1995 • 78 citations

Hinge and Amino-Terminal Sequences Contribute to Solution Dimerization of Human Progesterone Receptor

1997 • 73 citations

Role of Phosphorylation on DNA Binding and Transcriptional Functions of Human Progesterone Receptors

1996 • 64 citations

In vivo evidence against the existence of antiprogestins disrupting receptor binding to DNA.

1993 • 55 citations

Two Types of Anti-progestins Have Distinct Effects on Site-specific Phosphorylation of Human Progesterone Receptor

1996 • 55 citations

The Antagonists RU486 and ZK98299 Stimulate Progesterone Receptor Binding to Deoxyribonucleic Acid in Vitro and in Vivo, but Have Distinct Effects on Receptor Conformation*

1998 • 53 citations

Effects of the steroid antagonist RU486 on dimerization of the human progesterone receptor

1992 • 52 citations

Phosphorylation of Ser530 facilitates hormone-dependent transcriptional activation of the chicken progesterone receptor.

1994 • 42 citations

Phosphorylation of Ser211 in the Chicken Progesterone Receptor Modulates its Transcriptional Activity

1996 • 41 citations

Stoichiometry and Site-specific Phosphorylation of Human Progesterone Receptor in Native Target Cells and in the Baculovirus Expression System

1996 • 31 citations

Modulators of cellular protein phosphorylation alter thetrans-activation function of human progesterone receptor and the biological activity of progesterone antagonists

1993 • 30 citations

Phosphorylation of Ser530 facilitates hormone-dependent transcriptional activation of the chicken progesterone receptor

1994 • 21 citations

[19] Synthesis of O-phosphotyrosine-containing peptides

1991 • 13 citations

[18] Synthesis of O-phosphoserine- and O-phosphothreonine-containing peptides

1991 • 12 citations

Deleted Work

1955 • 0 citations