Oyster IKK‐like protein shares structural and functional properties with its mammalian homologues

Improved tools for biological sequence comparison.

1988 • 11,455 citations

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1997 • 5,522 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

1992 • 5,105 citations

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

1996 • 3,854 citations

NF-κB: Ten Years After

1996 • 3,008 citations

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1997 • 2,137 citations

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

1997 • 2,048 citations

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

1997 • 1,802 citations

MyD88 Is an Adaptor Protein in the hToll/IL-1 Receptor Family Signaling Pathways

1998 • 1,565 citations

The Arabidopsis NPR1 Gene That Controls Systemic Acquired Resistance Encodes a Novel Protein Containing Ankyrin Repeats

1997 • 1,522 citations

Map-Based Cloning of a Protein Kinase Gene Conferring Disease Resistance in Tomato

1993 • 1,423 citations

The product of the tobacco mosaic virus resistance gene N: Similarity to toll and the interleukin-1 receptor

1994 • 1,323 citations

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

1997 • 1,198 citations

Identification and Characterization of an IκB Kinase

1997 • 1,166 citations

MyD88: An Adapter That Recruits IRAK to the IL-1 Receptor Complex

1997 • 1,104 citations

IRAK: A Kinase Associated with the Interleukin-1 Receptor

1996 • 894 citations

Distribution and cloning of eukaryotic mRNAs by means of differential display: refinements and optimization

1993 • 874 citations

Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation

1999 • 855 citations

A CONSERVED SIGNALING PATHWAY: The Drosophila Toll-Dorsal Pathway

1996 • 822 citations

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors.

1993 • 819 citations

IκB-β regulates the persistent response in a biphasic activation of NF-κB

1995 • 780 citations

The Toll-receptor family and control of innate immunity

1999 • 666 citations

Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants

1998 • 573 citations

NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176

1998 • 533 citations

Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1998 • 531 citations

The Arabidopsis NIM1 protein shows homology to the mammalian transcription factor inhibitor I kappa B.

1997 • 480 citations

Molecular mechanisms of immune responses in insects.

1998 • 472 citations

The L6 gene for flax rust resistance is related to the Arabidopsis bacterial resistance gene RPS2 and the tobacco viral resistance gene N.

1995 • 470 citations

Dif, a dorsal-related gene that mediates an immune response in Drosophila

1993 • 464 citations

I kappa B epsilon, a novel member of the Ikappa B family, controls RelA and cRel NF-kappa B activity

1997 • 394 citations

The tomato gene Pti1 encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive response

1995 • 386 citations

Antimicrobial peptides of vertebrates

1998 • 377 citations

Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defense of Drosophila.

1996 • 357 citations

Innate Immunity

1996 • 355 citations

An ancient system of host defense

1998 • 333 citations

IKAP is a scaffold protein of the IκB kinase complex

1998 • 294 citations

κB-like Motifs Regulate the Induction of Immune Genes in Drosophila

1993 • 229 citations

Hydrolytic enzymes associated with the granular haemocytes of the marine musselMytilus edulis

1990 • 205 citations

A Member of the Arthropod Defensin Family from Edible Mediterranean Mussels (Mytilus galloprovincialis)

1996 • 183 citations

Antimicrobial peptide defense in Drosophila

1997 • 180 citations

Knowledge and research prospects in marine mollusc and crustacean immunology

1995 • 172 citations

Insect immunity. Two 17 bp repeats nesting a kappa B-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila.

1993 • 159 citations

Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene.

1993 • 155 citations

The Transcription Factor Spi-1/PU.1 Interacts with the Potential Splicing Factor TLS

1998 • 137 citations

Interaction of immunoactive monokines (interleukin 1 and tumor necrosis factor) in the bivalve mollusc Mytilus edulis.

1990 • 128 citations

Lumhol-dependent chemiluminescence by hemocytes of two marine bivalves, Ostrea edulis and Crassostrea gigas

1991 • 112 citations

Immune factor Gambif1, a new rel family member from the human malaria vector, Anopheles gambiae.

1996 • 109 citations

In Vivo Regulation of the IκB Homologue cactus during the Immune Response of Drosophila

1998 • 107 citations

A lectin on the hemocyte membrane of the oyster (Crassostrea virginica)

1984 • 89 citations

Agglutinin activity in pacific oyster (Crassostrea gigas) hemolymph following in vivo Vibrio anguillarum challenge

1992 • 78 citations

An antibody that binds the immunoglobulin CDR3-like region of the CD4 molecule inhibits provirus transcription in HIV-infected T cells.

1993 • 73 citations

The cytoplasmic domain of CD4 plays a critical role during the early stages of HIV infection in T-cells.

1994 • 73 citations

Interactions between Bonamia ostreae (Protozoa: Ascetospora) and hemocytes of Ostrea edulis and Crassostrea gigas (Mollusca: Bivalvia): Entry mechanisms

1992 • 54 citations

Structure and differential target sensitivity of the stimulable cytotoxic complex from hemolymph of the Mediterranean mussel Mytilus galloprovincialis

1997 • 29 citations

Biphasic action of growth hormone on intestinal amino acid absorption in striped bass hybrids

1992 • 21 citations

Theory of control of chaos using sampled data

1998 • 13 citations