IKAP is a scaffold protein of the IκB kinase complex

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB: Ten Years After

1996 • 3,008 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1997 • 2,137 citations

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

1997 • 2,048 citations

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

1997 • 1,802 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

The ancient regulatory-protein family of WD-repeat proteins

1994 • 1,478 citations

Control of IκB-α Proteolysis by Site-Specific, Signal-Induced Phosphorylation

1995 • 1,443 citations

MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

1997 • 1,294 citations

TRAF6 is a signal transducer for interleukin-1

1996 • 1,287 citations

NF-κB: A lesson in family values

1995 • 1,266 citations

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

1997 • 1,198 citations

Identification and Characterization of an IκB Kinase

1997 • 1,166 citations

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli.

1995 • 1,010 citations

IRAK: A Kinase Associated with the Interleukin-1 Receptor

1996 • 894 citations

Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†

1996 • 717 citations

Coupling of a Signal Response Domain in IκBα to Multiple Pathways for NF-κB Activation

1995 • 706 citations

NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules.

1997 • 576 citations

NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176

1998 • 533 citations

Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1998 • 531 citations

Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae

1994 • 499 citations

NF-κB Activation: The IκB Kinase Revealed?

1997 • 492 citations

NF-κB as a Frequent Target for Immunosuppressive and Anti-Inflammatory Molecules**This article was accepted for publication on 27 September 1996.

1997 • 472 citations

Rotation of photoreceptor clusters in the developing drosophila eye requires the nemo gene

1994 • 342 citations

Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade.

1994 • 329 citations

Pro-inflammatory signaling: Last pieces in the NF-κB puzzle?

1998 • 280 citations

Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module.

1994 • 243 citations

Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus

1998 • 172 citations

Identification of hepatic nuclear factor 1 binding sites in the 5′ flanking region of the human phenylalanine hydroxylase gene: Implication of a dual function of phenylalanine hydroxylase stimulator in the phenylalanine hydroxylation system

1998 • 28 citations

Characterization ofIKI1andIKI3Genes Conferring pGKL Killer Sensitivity onSaccharomyces cerevisiae

1997 • 26 citations

NF-κB: A Mediator of Pathogen and Stress Responses

1995 • 23 citations