The Double Bromodomain-containing Chromatin Adaptor Brd4 and Transcriptional Regulation

The Bromodomain Protein Brd4 Is a Positive Regulatory Component of P-TEFb and Stimulates RNA Polymerase II-Dependent Transcription

2005 • 1,209 citations

Recruitment of P-TEFb for Stimulation of Transcriptional Elongation by the Bromodomain Protein Brd4

2005 • 1,073 citations

The General Transcription Machinery and General Cofactors

2006 • 869 citations

Bromodomain: an acetyl‐lysine binding domain

2002 • 722 citations

The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

2003 • 635 citations

BRD4-NUT Fusion Oncogene: A Novel Mechanism in Aggressive Carcinoma

2003 • 471 citations

Global Nature of Dynamic Protein-Chromatin Interactions In Vivo: Three-Dimensional Genome Scanning and Dynamic Interaction Networks of Chromatin Proteins

2004 • 454 citations

Interaction of the Bovine Papillomavirus E2 Protein with Brd4 Tethers the Viral DNA to Host Mitotic Chromosomes

2004 • 395 citations

Selective Recognition of Acetylated Histones by Bromodomain Proteins Visualized in Living Cells

2004 • 353 citations

Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways

1998 • 305 citations

Growth and Early Postimplantation Defects in Mice Deficient for the Bromodomain-Containing Protein Brd4

2002 • 305 citations

Proteomics of the Eukaryotic Transcription Machinery: Identification of Proteins Associated with Components of Yeast TFIID by Multidimensional Mass Spectrometry

2002 • 292 citations

A Bromodomain Protein, MCAP, Associates with Mitotic Chromosomes and Affects G₂-to-M Transition

2000 • 281 citations

Acetylation-Dependent Chromatin Reorganization by BRDT, a Testis-Specific Bromodomain-Containing Protein

2003 • 274 citations

Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks

2006 • 261 citations

Bromodomains Mediate an Acetyl-Histone Encoded Antisilencing Function at Heterochromatin Boundaries

2003 • 233 citations

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

1996 • 228 citations

Brd4 links chromatin targeting to HPV transcriptional silencing

2006 • 208 citations

Bromodomain factor 1 corresponds to a missing piece of yeast TFIID

2000 • 200 citations

E6 Oncoprotein Represses p53-Dependent Gene Activation via Inhibition of Protein Acetylation Independently of Inducing p53 Degradation

2005 • 199 citations

Different Sensitivities of Bromodomain Factors 1 and 2 to Histone H4 Acetylation

2003 • 184 citations

Brd4 Is Required for E2-Mediated Transcriptional Activation but Not Genome Partitioning of All Papillomaviruses

2006 • 178 citations

A Mammalian Bromodomain Protein, Brd4, Interacts with Replication Factor C and Inhibits Progression to S Phase

2002 • 167 citations

You bet-cha: a novel family of transcriptional regulators

2001 • 163 citations

RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F.

2000 • 156 citations

Kaposi's Sarcoma-Associated Herpesvirus LANA-1 Interacts with the Short Variant of BRD4 and Releases Cells from a BRD4- and BRD2/RING3-Induced G ₁ Cell CycleArrest

2006 • 142 citations

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Interacts with Bromodomain Protein Brd4 on Host Mitotic Chromosomes

2006 • 139 citations

Bromodomain Protein 4 Mediates the Papillomavirus E2 Transcriptional Activation Function

2006 • 133 citations

ChlR1 Is Required for Loading Papillomavirus E2 onto Mitotic Chromosomes and Viral Genome Maintenance

2006 • 117 citations

Structure of the Papillomavirus DNA-Tethering Complex E2:Brd4 and a Peptide that Ablates HPV Chromosomal Association

2006 • 116 citations

Crystal Structure of the Human BRD2 Bromodomain

2006 • 113 citations

Variations in the association of papillomavirus E2 proteins with mitotic chromosomes

2006 • 112 citations

Identification of unique, differentiation stage-specific patterns of expression of the bromodomain-containing genes Brd2, Brd3, Brd4, and Brdt in the mouse testis

2004 • 110 citations

The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells

2006 • 107 citations

Bdf1, a Yeast Chromosomal Protein Required for Sporulation

1995 • 107 citations

Human papillomavirus (HPV) origin-binding protein associates with mitotic spindles to enable viral DNA partitioning

2004 • 100 citations

Brd4 Is Involved in Multiple Processes of the Bovine Papillomavirus Type 1 Life Cycle

2006 • 81 citations

Brd4 Is Required for Recovery from Antimicrotubule Drug-induced Mitotic Arrest: Preservation of Acetylated Chromatin

2005 • 75 citations

Bromodomain Protein Brd4 Binds to GTPase-Activating SPA-1, Modulating Its Activity and Subcellular Localization

2004 • 73 citations

Human Mediator Enhances Activator-Facilitated Recruitment of RNA Polymerase II and Promoter Recognition by TATA-Binding Protein (TBP) Independently of TBP-Associated Factors

2003 • 59 citations

Transcriptional Activity among High and Low Risk Human Papillomavirus E2 Proteins Correlates with E2 DNA Binding

2002 • 53 citations

TATA-binding Protein-associated Factors Enhance the Recruitment of RNA Polymerase II by Transcriptional Activators

2001 • 52 citations

Alleviation of Human Papillomavirus E2-Mediated Transcriptional Repression via Formation of a TATA Binding Protein (or TFIID)-TFIIB-RNA Polymerase II-TFIIF Preinitiation Complex

2000 • 52 citations

TAFII-independent activation mediated by human TBP in the presence of the positive cofactor PC4

1998 • 49 citations

Dynamic Localization of the Human Papillomavirus Type 11 Origin Binding Protein E2 through Mitosis While in Association with the Spindle Apparatus

2006 • 45 citations

Cloned fusion product from a rare t(15;19)(q13.2;p13.1) inhibit S phase in vitro

2005 • 43 citations

Bromodomain testis-specific protein is expressed in mouse oocyte and evolves faster than its ubiquitously expressed paralogs BRD2, -3, and -4

2006 • 40 citations

Genome dynamics of the major histocompatibility complex: insights from genome paralogy

1999 • 39 citations

Characterization of the Functional Activities of the Bovine Papillomavirus Type 1 E2 Protein Single-Chain Heterodimers

2006 • 26 citations