Brd4 Is Required for Recovery from Antimicrotubule Drug-induced Mitotic Arrest: Preservation of Acetylated Chromatin

Microtubules as a target for anticancer drugs

2004 • 4,193 citations

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

2000 • 3,564 citations

Mitotic kinases as regulators of cell division and its checkpoints

2001 • 1,503 citations

The Bromodomain Protein Brd4 Is a Positive Regulatory Component of P-TEFb and Stimulates RNA Polymerase II-Dependent Transcription

2005 • 1,209 citations

BCL-2 Is Phosphorylated and Inactivated by an ASK1/Jun N-Terminal Protein Kinase Pathway Normally Activated at G₂/M

1999 • 997 citations

Centromeres and Kinetochores

2003 • 967 citations

The Anaphase-Promoting Complex

2002 • 885 citations

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation.

1993 • 795 citations

Trichostatin A and trapoxin: Novel chemical probes for the role of histone acetylation in chromatin structure and function

1995 • 719 citations

Temporal and spatial control of cyclin B1 destruction in metaphase

1999 • 685 citations

The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

2003 • 635 citations

Stuck in Division or Passing through

2004 • 630 citations

Merotelic Kinetochore Orientation Is a Major Mechanism of Aneuploidy in Mitotic Mammalian Tissue Cells

2001 • 556 citations

Microtubule-targeted anticancer agents and apoptosis

2003 • 448 citations

The bromodomain: a conserved sequence found in human,Drosophilaand yeast proteins

1992 • 375 citations

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

2000 • 366 citations

The spindle assembly checkpoint

1996 • 364 citations

Mitotic repression of the transcriptional machinery

1997 • 364 citations

Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases

2001 • 355 citations

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

1998 • 353 citations

Selective Recognition of Acetylated Histones by Bromodomain Proteins Visualized in Living Cells

2004 • 353 citations

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.

1994 • 319 citations

Growth and Early Postimplantation Defects in Mice Deficient for the Bromodomain-Containing Protein Brd4

2002 • 305 citations

A Bromodomain Protein, MCAP, Associates with Mitotic Chromosomes and Affects G₂-to-M Transition

2000 • 281 citations

Mitosis: a history of division

2001 • 265 citations

Activation of the Protein Kinase p38 in the Spindle Assembly Checkpoint and Mitotic Arrest

1998 • 264 citations

ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure.

1994 • 252 citations

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

1996 • 228 citations

Coupling cell division and cell death to microtubule dynamics

1997 • 228 citations

Regulation of Global Acetylation in Mitosis through Loss of Histone Acetyltransferases and Deacetylases from Chromatin

2001 • 206 citations

Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization.

1996 • 200 citations

Re-staging mitosis: a contemporary view of mitotic progression

2001 • 189 citations

Histone Hyperacetylation in Mitosis Prevents Sister Chromatid Separation and Produces Chromosome Segregation Defects

2003 • 177 citations

A Mammalian Bromodomain Protein, Brd4, Interacts with Replication Factor C and Inhibits Progression to S Phase

2002 • 167 citations

Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway

2004 • 151 citations

Sequential Entry of Components of Gene Expression Machinery into Daughter Nuclei

2003 • 143 citations

Proteome Analysis of Human Metaphase Chromosomes

2005 • 130 citations

Improved methods for the isolation of individual and clustered mitotic chromosomes

1987 • 72 citations

Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells

1999 • 71 citations

Intra-oocyte Localization of MAD2 and Its Relationship with Kinetochores, Microtubules, and Chromosomes in Rat Oocytes During Meiosis1

2004 • 60 citations

Bromodomains in living cells participate in deciphering the histone code

2004 • 38 citations

Cell Cycle: Stressed Out of Mitosis

2002 • 34 citations