Characterization of the Functional Activities of the Bovine Papillomavirus Type 1 E2 Protein Single-Chain Heterodimers
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Abstract
References (31)
Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames.
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Interaction of the Bovine Papillomavirus E2 Protein with Brd4 Tethers the Viral DNA to Host Mitotic Chromosomes
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Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA
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E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain.
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The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity.
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Bromodomain Protein 4 Mediates the Papillomavirus E2 Transcriptional Activation Function
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The E8^E2C Protein, a Negative Regulator of Viral Transcription and Replication, Is Required for Extrachromosomal Maintenance of Human Papillomavirus Type 31 in Keratinocytes
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The Mitotic Chromosome Binding Activity of the Papillomavirus E2 Protein Correlates with Interaction with the Cellular Chromosomal Protein, Brd4
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Interaction of the Papillomavirus E2 Protein with Mitotic Chromosomes
2000 • 119 citations
Bovine papilloma virus-transformed cells contain multiple E2 proteins.
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Brd4 Is Involved in Multiple Processes of the Bovine Papillomavirus Type 1 Life Cycle
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Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants
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Genetic assignment of multiple E2 gene products in bovine papillomavirus-transformed cells
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Cooperative activation of transcription by bovine papillomavirus type 1 E2 can occur over a large distance.
1990 • 66 citations
An E1M--E2C fusion protein encoded by human papillomavirus type 11 is asequence-specific transcription repressor
1991 • 65 citations
Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants
1996 • 65 citations
Amino acids necessary for DNA contact and dimerization imply novel motifs in the papillomavirus E2 trans-activator.
1992 • 56 citations
Transcription Factor E2 Regulates BPV-1 DNA Replication In Vitro by Direct Protein-Protein Interaction
1991 • 53 citations
Analysis of Chromatin Attachment and Partitioning Functions of Bovine Papillomavirus Type 1 E2 Protein
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Mechanism of action of the papillomavirus E2 repressor: repression in the absence of DNA binding
1992 • 49 citations
A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention
1997 • 34 citations
Effect of Bovine Papillomavirus E2 Protein-Specific Monoclonal Antibodies on Papillomavirus DNA Replication
1999 • 34 citations
Competition for DNA Binding Sites between the Short and Long Forms of E2 Dimers Underlies Repression in Bovine Papillomavirus Type 1 DNA Replication Control
1998 • 33 citations
Structural Correlates for Enhanced Stability in the E2 DNA-Binding Domain from Bovine Papillomavirus,
1999 • 23 citations
Thermodynamics of DNA binding of MM17, a single chain dimer' of transcription factor MASH-1
2000 • 21 citations
Association of Bovine Papillomavirus E2 Protein with Nuclear Structures In Vivo
2005 • 19 citations
Synergistic transcriptional-activation by the papillomavirus E2 protein occurs after DNA binding and correlates with a change in chromatin structure 1 1Edited by J. Karn
1997 • 15 citations
Cooperative Activation of Transcription by Bovine Papillomavirus Type 1 E2 Can Occur over a Large Distance
1990 • 12 citations