Cysteine-3635 is responsible for skeletal muscle ryanodine receptor modulation by NO

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle

1994 • 1,704 citations

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor

1989 • 1,132 citations

Physiology of Nitric Oxide in Skeletal Muscle

2001 • 1,053 citations

Activation of the Cardiac Calcium Release Channel (Ryanodine Receptor) by Poly-S-Nitrosylation

1998 • 983 citations

Ryanodine Receptor/Ca2+ Release Channels and Their Regulation by Endogenous Effectors

1994 • 908 citations

Fas-Induced Caspase Denitrosylation

1999 • 742 citations

Ryanodine receptors of striated muscles: a complex channel capable of multiple interactions

1997 • 690 citations

(S)NO Signals: Translocation, Regulation, and a Consensus Motif

1997 • 680 citations

Accelerated reaction of nitric oxide with O ₂ within the hydrophobic interior of biological membranes

1998 • 590 citations

Reactions between nitric oxide and haemoglobin under physiological conditions

1998 • 577 citations

A Molecular Redox Switch on p21

1997 • 488 citations

Redox modulation of L-type calcium channels in ferret ventricular myocytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols.

1996 • 444 citations

The Skeletal Muscle Calcium Release Channel

2000 • 429 citations

Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation

2000 • 417 citations

Adenine nucleotide stimulation of Ca2+-induced Ca2+ release in sarcoplasmic reticulum.

1984 • 373 citations

Calmodulin activation and inhibition of skeletal muscle Ca2+ release channel (ryanodine receptor)

1995 • 299 citations

Nitric oxide activates skeletal and cardiac ryanodine receptors

1997 • 261 citations

Calmodulin Binding and Inhibition of Cardiac Muscle Calcium Release Channel (Ryanodine Receptor)

2001 • 217 citations

S-Nitrosylation of proteins

1999 • 211 citations

Methionine Adenosyltransferase S-Nitrosylation Is Regulated by the Basic and Acidic Amino Acids Surrounding the Target Thiol

1999 • 155 citations

Classes of Thiols That Influence the Activity of the Skeletal Muscle Calcium Release Channel

2001 • 154 citations

NO hyperpolarizes pulmonary artery smooth muscle cells and decreases the intracellular Ca2+ concentration by activating voltage-gated K+ channels.

1996 • 153 citations

Inhibition of the skeletal muscle ryanodine receptor calcium release channel by nitric oxide

1996 • 150 citations

Critical sulfhydryls regulate calcium release from sarcoplasmic reticulum

1989 • 149 citations

Transmembrane Redox Sensor of Ryanodine Receptor Complex

2000 • 145 citations

Evidence for a Role of the Lumenal M3-M4 Loop in Skeletal Muscle Ca2+ Release Channel (Ryanodine Receptor) Activity and Conductance

2000 • 142 citations

Nitric Oxide as an Autocrine Regulator of Sodium Currents in Baroreceptor Neurons

1998 • 141 citations

An autocatalytic mechanism of protein nitrosylation

2000 • 141 citations

Apocalmodulin and Ca²⁺ Calmodulin Bind to the Same Region on the Skeletal Muscle Ca²⁺ Release Channel

1999 • 138 citations

Glutathione Modulates Ryanodine Receptor from Skeletal Muscle Sarcoplasmic Reticulum

1997 • 131 citations

Nitric Oxide Protects the Skeletal Muscle Ca2+Release Channel from Oxidation Induced Activation

1997 • 130 citations

Calcium Binding to Calmodulin Leads to an N-terminal Shift in Its Binding Site on the Ryanodine Receptor

2001 • 125 citations

Skeletal Muscle Ryanodine Receptor Is a Redox Sensor with a Well Defined Redox Potential That Is Sensitive to Channel Modulators

2000 • 124 citations

Inactivation of the cardiac ryanodine receptor calcium release channel by nitric oxide

1997 • 118 citations

Identification of Apocalmodulin and Ca2+-Calmodulin Regulatory Domain in Skeletal Muscle Ca2+ Release Channel, Ryanodine Receptor

2001 • 99 citations

Nitric Oxide Activates or Inhibits Skeletal Muscle Ryanodine Receptors Depending on Its Concentration, Membrane Potential and Ligand Binding

2000 • 96 citations

Regulation of ryanodine receptors by reactive nitrogen species

1999 • 95 citations

A Role for Cysteine 3635 of RYR1 in Redox Modulation and Calmodulin Binding

1999 • 84 citations

A Single Intracellular Cysteine Residue Is Responsible for the Activation of the Olfactory Cyclic Nucleotide-gated Channel by NO

2000 • 76 citations

Evidence for a role of C‐terminal amino acid residues in skeletal muscle Ca²⁺ release channel (ryanodine receptor) function

1997 • 63 citations

Molecular Interaction Between Nitric Oxide and Ryanodine Receptors of Skeletal and Cardiac Sarcoplasmic Reticulum

2000 • 50 citations