VE-cadherin-induced Cdc42 Signaling Regulates Formation of Membrane Protrusions in Endothelial Cells

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Morphogenetic roles of classic cadherins

1995 • 1,468 citations

The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.

1989 • 1,393 citations

Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis

1999 • 1,291 citations

HMEC-1: Establishment of an Immortalized Human Microvascular Endothelial Cell Line

1992 • 1,258 citations

Cytoskeletal regulation of pulmonary vascular permeability

2001 • 954 citations

Regulation of Cadherin Adhesive Activity

2000 • 793 citations

The Structure of the β-Catenin/E-Cadherin Complex and the Molecular Basis of Diverse Ligand Recognition by β-Catenin

2001 • 737 citations

Latrunculins: Novel Marine Toxins That Disrupt Microfilament Organization in Cultured Cells

1983 • 736 citations

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor.

1994 • 712 citations

Developmental Defects in Mouse Embryos Lacking N-Cadherin

1997 • 712 citations

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members 1 1Edited by M. Yaniv

2000 • 682 citations

The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin).

1995 • 573 citations

P120 Catenin Regulates the Actin Cytoskeleton via Rho Family Gtpases

2000 • 563 citations

A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development.

1995 • 498 citations

Cadherins in embryonic and neural morphogenesis

2000 • 482 citations

Inhibition of RhoA by p120 catenin

2000 • 459 citations

Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion

2000 • 456 citations

Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling

1997 • 448 citations

Cadherin Engagement Regulates Rho family GTPases

2001 • 421 citations

Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain

1992 • 394 citations

Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions.

1996 • 334 citations

VE-cadherin antibody accelerates neutrophil recruitment in vivo

1997 • 314 citations

Differential Localization of VE- and N-Cadherins in Human Endothelial Cells: VE-Cadherin Competes with N-Cadherin for Junctional Localization

1998 • 297 citations

Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability

2001 • 293 citations

Making a connection: direct binding between keratin intermediate filaments and desmosomal proteins.

1994 • 283 citations

Activation of the Protein Kinase Akt/PKB by the Formation of E-cadherin-mediated Cell-Cell Junctions

1999 • 268 citations

Vinculin Is Part of the Cadherin–Catenin Junctional Complex: Complex Formation between α-Catenin and Vinculin

1998 • 260 citations

Precocious Mammary Gland Development in P-Cadherin–deficient Mice

1997 • 252 citations

E-cadherin-mediated Cell-Cell Attachment Activates Cdc42

2000 • 214 citations

Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated nonfunctional N-cadherin.

1993 • 199 citations

Monocytes Induce Reversible Focal Changes in Vascular Endothelial Cadherin Complex during Transendothelial Migration under Flow

2000 • 195 citations

Casein Kinase II Phosphorylation of E-cadherin Increases E-cadherin/β-Catenin Interaction and Strengthens Cell-Cell Adhesion

2000 • 193 citations

Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks.

1993 • 178 citations

Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes

1996 • 165 citations

Regulation of endothelial barrier function and growth by VE-cadherin, plakoglobin, and β-catenin

2002 • 119 citations

The molecular organization of endothelial junctions and their functional role in vascular morphogenesis and permeability.

2000 • 115 citations

Mechanism of extracellular domain-deleted dominant negative cadherins

1999 • 90 citations

N-cadherin in adult rat cardiomyocytes in culture. I. Functional role of N-cadherin and impairment of cell-cell contact by a truncated N-cadherin mutant

1996 • 89 citations

The role of endothelial cell lateral junctions during leukocyte trafficking

2002 • 67 citations

Differential perturbations in the morphogenesis of anterior structures induced by overexpression of truncated XB- and N-cadherins in Xenopus embryos.

1994 • 65 citations

The Dual Role of Cytoskeletal Anchor Proteins in Cell Adhesion and Signal Transduction

1999 • 38 citations