Complete inventory of the yeast ABC proteins

Basic local alignment search tool

1990 • 87,358 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

The P-loop — a common motif in ATP- and GTP-binding proteins

1990 • 2,029 citations

A knowledge base for predicting protein localization sites in eukaryotic cells

1992 • 1,518 citations

Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

1993 • 1,175 citations

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

1996 • 827 citations

Mutations in the Sulfonylurea Receptor Gene in Familial Persistent Hyperinsulinemic Hypoglycemia of Infancy

1995 • 812 citations

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

1995 • 805 citations

Acylation Targets Endothelial Nitric-oxide Synthase to Plasmalemmal Caveolae

1996 • 798 citations

CYSTIC FIBROSIS: GENOTYPIC AND PHENOTYPIC VARIATIONS

1995 • 613 citations

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

1989 • 604 citations

The yeast genome project: what did we learn?

1996 • 540 citations

Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals

1995 • 476 citations

GENETIC ANALYSIS OF THE MULTIDRUG TRANSPORTER

1995 • 469 citations

Transport of Metal-binding Peptides by HMT1, A Fission Yeast ABC-type Vacuolar Membrane Protein

1995 • 468 citations

Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.

1989 • 443 citations

The Yeast Cadmium Factor Protein (YCF1) Is a Vacuolar Glutathione S-Conjugate Pump

1996 • 442 citations

PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1.

1994 • 439 citations

A cluster of cystic fibrosis mutations in the first nucleotide-binding fold of the cystic fibrosis conductance regulator protein

1990 • 397 citations

Complete DNA sequence of yeast chromosome XI

1994 • 377 citations

A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein.

1994 • 364 citations

Homozygous Human TAP Peptide Transporter Mutation in HLA Class I Deficiency

1994 • 348 citations

The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae.

1996 • 319 citations

Anticancer Drugs, Ionophoric Peptides, and Steroids as Substrates of the Yeast Multidrug Transporter Pdr5p

1996 • 314 citations

DNA sequence of the white locus of Drosophila melanogaster

1984 • 282 citations

Complete Nucleotide Sequence of Saccharomyces cerevisiae Chromosome VIII

1994 • 279 citations

Computer-aided analyses of transport protein sequences: gleaning evidence concerning function, structure, biogenesis, and evolution

1994 • 263 citations

Evolution of ATP-binding cassette transporter genes

1995 • 249 citations

Cloning and Characterization of a RNase L Inhibitor.

1995 • 243 citations

Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance.

1994 • 231 citations

Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome

1992 • 228 citations

The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes.

1988 • 224 citations

Molecular genetic analysis of a locus required for resistance to antimicrobial peptides in Salmonella typhimurium.

1993 • 221 citations

A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.

1996 • 221 citations

Cadmium tolerance mediated by the yeast AP-1 protein requires the presence of an ATP-binding cassette transporter-encoding gene, YCF1.

1994 • 214 citations

Expression of an ATP-Binding Cassette Transporter-Encoding Gene (YOR1) Is Required for Oligomycin Resistance in Saccharomyces cerevisiae

1995 • 214 citations

An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast.

1995 • 200 citations

Gene SNQ2 of Saccharomyces cerevislae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases

1993 • 198 citations

Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces.

1990 • 184 citations

GCN20, a novel ATP binding cassette protein, and GCN1 reside in a complex that mediates activation of the eIF-2 alpha kinase GCN2 in amino acid-starved cells.

1995 • 175 citations

The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1.

1996 • 170 citations

Identification and Characterization of SNQ2, a New Multidrug ATP Binding Cassette Transporter of the Yeast Plasma Membrane

1995 • 161 citations

Saccharomyces cerevisiae YDR1, which encodes a member of the ATP-binding cassette (ABC) superfamily, is required for multidrug resistance

1994 • 150 citations

Sequence of a staphylococcal plasmid gene, vga, encoding a putative ATP-binding protein involved in resistance to virginiamycin A-like antibiotics

1992 • 147 citations

Bacterial binding protein‐dependent permeases: characterization of distinctive signatures for functionally related integral cytoplasmic membrane proteins

1994 • 134 citations

PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene.

1995 • 129 citations

Solubilization and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast.

1994 • 118 citations

Topology of the hydrophobic membrane-bound components of the histidine periplasmic permease. Comparison with other members of the family.

1992 • 110 citations

Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae

1995 • 107 citations

Hormonal and Environmental Regulation of a Plant PDR5-like ABC Transporter

1996 • 102 citations

Effect of Cystic Fibrosis-associated Mutations in the Fourth Intracellular Loop of Cystic Fibrosis Transmembrane Conductance Regulator

1996 • 98 citations

RETRACTED: ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter.

1996 • 87 citations

Sequence analysis of the translational elongation factor 3 from Saccharomyces cerevisiae.

1990 • 86 citations

Computer-aided analyses of transport protein sequences: gleaning evidence concerning function, structure, biogenesis, and evolution.

1994 • 81 citations

Protein synthesis in yeast. Structural and functional analysis of the gene encoding elongation factor 3.

1990 • 78 citations

Hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Use of site-directed mutagenesis to evaluate the roles of His-258 and His-392 in catalysis.

1990 • 76 citations

bfr1+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily

1995 • 71 citations

Intracellular Loop between Transmembrane Segments IV and V of Cystic Fibrosis Transmembrane Conductance Regulator Is Involved in Regulation of Chloride Channel Conductance State

1995 • 71 citations

<scp>XII</scp><scp>XVI</scp>. Yeast sequencing reports. Mapping and sequencing of two yeast genes belonging to the ATP‐binding cassette superfamily

1994 • 69 citations

Molecular cloning of a mammalian ABC transporter homologous to Drosophila white gene

1996 • 69 citations

Sequence Comparison of Yeast ATP-binding Cassette Proteins

1995 • 65 citations

Characterization and Analysis of Conserved Motifs in a Peroxisomal ATP-binding Cassette Transporter

1996 • 59 citations

The membrane proteins encoded by yeast chromosome III genes

1993 • 48 citations

How many yeast genes code for membrane-spanning proteins?

1993 • 45 citations

Evolution of the ATP-binding-cassette transmembrane transporters of vertebrates.

1994 • 45 citations

The yeast genome — a common currency

1996 • 44 citations

<scp>XI</scp>. Yeast sequencing reports. The yeast YKL741 gene situated on the left arm of chromosome XI codes for a homologue of the human ALD protein

1994 • 41 citations

The product of the YCR105 gene located on the chromosome III from Saccharomyces cerevisiae presents homologies to ATP‐dependent permeases

1991 • 39 citations

Insulin‐dependent diabetes mellitus and the major histocompatibility complex peptide transporters TAP1 and TAP2: no association in a population with a high disease incidence

1994 • 34 citations

Genetic Analysis of the Multidrug Transporter

1995 • 31 citations

TAP polymorphism in patients with Behcet's disease.

1995 • 28 citations

Genes in search of functions

1994 • 27 citations

Isolation and characterization of additional genes influencing resistance to various mutagens in the yeast Saccharomyces cerevisiae

1992 • 27 citations

Multidrug resistance in Entamoeba histolytica

1995 • 23 citations

TAP1 and TAP2 polymorphism in multiple sclerosis patients

1994 • 23 citations

Inhibition of protein synthesis disrupts the golgi apparatus in the fission yeast, Schizosaccharomyces pombe

1994 • 17 citations

Transport of Proteins and Metabolites across the Impermeable Membrane of Peroxisomes

1995 • 17 citations

Sequence analysis of the CEN12 region of Saccharomyces cerevisiae on a 43·7 kb fragment of chromosome XII including an open reading frame homologous to the human cystic fibrosis transmembrane conductance regulator protein CFTR

1996 • 10 citations