bfr1+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

ABC Transporters: From Microorganisms to Man

1992 • 3,956 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

The P-loop — a common motif in ATP- and GTP-binding proteins

1990 • 2,029 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

1992 • 741 citations

Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF

1992 • 736 citations

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

1989 • 604 citations

Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.

1989 • 443 citations

PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1.

1994 • 439 citations

Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance.

1989 • 303 citations

DNA sequence of the white locus of Drosophila melanogaster

1984 • 282 citations

Targeted selection of recombinant clones through gene dosage effects.

1983 • 262 citations

Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance.

1994 • 231 citations

The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes.

1988 • 224 citations

Gene SNQ2 of Saccharomyces cerevislae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases

1993 • 198 citations

Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily.

1991 • 188 citations

Structure and function of haemolysin B, P‐glycoprotein and other members of a novel family of membrane translocators

1990 • 183 citations

Saccharomyces cerevisiae YDR1, which encodes a member of the ATP-binding cassette (ABC) superfamily, is required for multidrug resistance

1994 • 150 citations

ATP‐dependent bacterial transporters and cystic fibrosis: analogy between channels and transporters

1992 • 107 citations

Brefeldin A, a specific inhibitor of intracellular translocation of vesicular stomatitis virus G protein: Intracellular accumulation of high-mannose type G protein and inhibition of its cell surface expression.

1985 • 104 citations

A leptomycin B resistance gene of Schizosaccharomyces pombe encodes a protein similar to the mammalian P‐glycoproteins

1992 • 79 citations

Discrete Mutations Introduced in the Predicted Nucleotide-Binding Sites of the mdr1 Gene Abolish Its Ability To Confer Multidrug Resistance

1989 • 57 citations

The Brown Protein of Drosophila melanogaster is Similar to the White Protein and to Components of Active Transport Complexes

1988 • 49 citations

Brefeldin A blocks an early stage of protein transport in Candida albicans

1991 • 16 citations

Brefeldin A, a Specific Inhibitor of Intracellular Translocation of Vesicular Stomatitis Virus G Protein: Intracellular Accumulation of High-mannose Type G Protein and Inhibition of Its Cell Surface Expression

1985 • 15 citations

Mating of the fission yeast occurs independently of pmd1 + gene product, a structural homologue of budding yeast STE6 and mammalian P-glycoproteins

1993 • 10 citations

Effect of brefeldin A on biosynthesis of cellular components in Candida albicans.

1982 • 9 citations