Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

ABC Transporters: From Microorganisms to Man

1992 • 3,956 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

Methods in Yeast Genetics — A Laboratory Course Manual

1991 • 1,257 citations

DNA sequence required for efficient transcription termination in yeast

1982 • 1,014 citations

The hydrophobic moment detects periodicity in protein hydrophobicity.

1984 • 877 citations

The detection and classification of membrane-spanning proteins

1985 • 854 citations

The structure of an antigenic determinant in a protein

1984 • 841 citations

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

1989 • 604 citations

Nucleotide sequence of an Escherichia coli chromosomal hemolysin

1985 • 572 citations

Glycoprotein biosynthesis in yeast

1993 • 514 citations

Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.

1989 • 443 citations

The structure of transposable yeast mating type loci

1980 • 439 citations

Inducible erythromycin resistance in staphlyococci is encoded by a member of the ATP‐binding transport super‐gene family

1990 • 366 citations

Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum.

1992 • 352 citations

Compilation and analysis of eukaryotic POL II promoter sequences

1986 • 345 citations

Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins.

1989 • 328 citations

DNA sequence of the white locus of Drosophila melanogaster

1984 • 282 citations

The multidrug resistance gene PDR1 from Saccharomyces cerevisiae.

1987 • 276 citations

The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene.

1990 • 259 citations

Heavy metal resistance: a new role for P-glycoproteins in Leishmania.

1991 • 231 citations

The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes.

1988 • 224 citations

A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin.

1991 • 221 citations

SHR3: A novel component of the secretory pathway specifically required for localization of amino acid permeases in yeast

1992 • 200 citations

Gene SNQ2 of Saccharomyces cerevislae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases

1993 • 198 citations

Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces.

1990 • 184 citations

Transcription terminates in yeast distal to a control sequence

1983 • 181 citations

The ndvA gene product of Rhizobium meliloti is required for beta-(1----2)glucan production and has homology to the ATP-binding export protein HlyB

1988 • 165 citations

Expression of the yeast plasma membrane [H+]ATPase in secretory vesicles. A new strategy for directed mutagenesis.

1991 • 152 citations

Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5

1992 • 149 citations

Role for [corrected] Agrobacterium tumefaciens ChvA protein in export of beta-1,2-glucan

1989 • 138 citations

Genetic basis of multidrug resistance of tumor cells

1990 • 124 citations

SKN1 and KRE6 define a pair of functional homologs encoding putative membrane proteins involved in beta-glucan synthesis.

1993 • 116 citations

The a-factor transporter (STE6 gene product) and cell polarity in the yeast Saccharomyces cerevisiae.

1993 • 97 citations

Multiple or pleiotropic drug resistance in yeast

1991 • 97 citations

Negative regulation of STE6 gene expression by the alpha 2 product of Saccharomyces cerevisiae.

1984 • 93 citations

Secretion of Peptides and Proteins Lacking Hydrophobic Signal Sequences: The Role of Adenosine Triphosphate-Driven Membrane Translocators*

1992 • 92 citations

Sec15 protein, an essential component of the exocytotic apparatus, is associated with the plasma membrane and with a soluble 19.5S particle.

1991 • 91 citations

Control of Saccharomyces cerevisiae Catalase T Gene (CTT1) Expression by Nutrient Supply via the RAS-Cyclic AMP Pathway

1989 • 87 citations

Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae.

1992 • 83 citations

The SNQ3 gene of Saccharomyces cerevisiae confers hyper-resistance to several functionally unrelated chemicals

1991 • 76 citations

Identification and characterization of a Saccharomyces cerevisiae gene (PAR1) conferring resistance to iron chelators

1991 • 76 citations

[30] Sequence and structural requirements for efficient translation in yeast

1990 • 42 citations

The product of the YCR105 gene located on the chromosome III from Saccharomyces cerevisiae presents homologies to ATP‐dependent permeases

1991 • 39 citations

Drug resistance and the P-glycoprotein homologues of Plasmodium falciparum

1993 • 28 citations

<scp>II</scp>. Yeast sequencing reports. Sequence of a 12·7 kb segment of yeast chromosome II identifies a PDR‐like gene and several new open reading frames

1992 • 26 citations

Isolation and characterization of the structural gene encoding elongation factor 3

1990 • 24 citations

In vitro and in vivo mutagenicity studies on sporidesmin, the toxin associated with facial eczema in ruminants

1992 • 11 citations

High-level resistance to cycloheximide resulting from an interaction of the mutated pdr3 and cyh genes in yeast

1992 • 6 citations