MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer

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Oncomirs — microRNAs with a role in cancer

2006 • 6,877 citations

A microRNA expression signature of human solid tumors defines cancer gene targets

2006 • 5,638 citations

TM4: A Free, Open-Source System for Microarray Data Management and Analysis

2003 • 4,724 citations

Silencing of microRNAs in vivo with ‘antagomirs’

2005 • 3,846 citations

Rising Incidence of Hepatocellular Carcinoma in the United States

1999 • 2,875 citations

MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells

2005 • 2,530 citations

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

2006 • 2,006 citations

Molecular pathogenesis of human hepatocellular carcinoma

2002 • 1,424 citations

Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis

2005 • 1,421 citations

Inhibition of Cell Migration, Spreading, and Focal Adhesions by Tumor Suppressor PTEN

1998 • 1,215 citations

Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues

2005 • 1,145 citations

MicroRNA-Cancer Connection: The Beginning of a New Tale

2006 • 1,048 citations

Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines

2006 • 970 citations

Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

2004 • 634 citations

Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas

2006 • 612 citations

MicroRNAs and cancer

2003 • 443 citations

Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma

2003 • 263 citations

Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell line

1999 • 208 citations

Overexpression of matrix metalloproteinase 9 gene in hepatocellular carcinoma with invasive potential

1996 • 206 citations

Overexpression of matrix metalloproteinase 9 gene in hepatocellular carcinoma with invasive potential

1996 • 179 citations

PTEN suppresses hyaluronic acid induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation

2002 • 153 citations

RRM1-induced metastasis suppression through PTEN-regulated pathways

2003 • 143 citations

Functional Genomics of Hepatocellular Carcinoma

2006 • 139 citations

Role of Expression of Focal Adhesion Kinase in Progression of Hepatocellular Carcinoma

2004 • 129 citations

Relation of enhanced secretion of active matrix metalloproteinases with tumor spread in human hepatocellular carcinoma

1997 • 120 citations

Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes

2005 • 119 citations

Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic factor

2004 • 102 citations

TIMP-1 inhibits microvascular endothelial cell migration by MMP-dependent and MMP-independent mechanisms

2004 • 97 citations

Tumours and tremors: how PTEN regulation underlies both

2006 • 85 citations

The alteration of PTEN tumor suppressor expression and its association with the histopathological features of human primary hepatocellular carcinoma

2003 • 36 citations