EXPRESSION OF THE MULTDORUG RESISTANCE GLYCOPROTEIN 170 IN THE PERIPHERAL BLOOD LYMPHOCYTES OF RHEUMATOID ARTHRITIS PATIENTS. THE PERCENTAGE OF LYMPHOCYTES EXPRESSING GLYCOPROTEIN 170 IS INCREASED IN PATIENTS TREATED WITH PREDNISOLONE

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1988 • 19,632 citations

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

1981 • 1,463 citations

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

1987 • 1,080 citations

Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins

1986 • 1,058 citations

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone.

1992 • 677 citations

Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy.

1989 • 565 citations

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells.

1988 • 480 citations

Amplification of a Gene Related to Mammalian mdr Genes in Drug-Resistant Plasmodium falciparum

1989 • 439 citations

The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

1986 • 410 citations

Cyclosporin A reverses vincristine and daunorubicin resistance in acute lymphatic leukemia in vitro.

1986 • 321 citations

Structure and expression of the human MDR (P-glycoprotein) gene family.

1989 • 296 citations

Termination of slow acting antirheumatic therapy in rheumatoid arthritis: a 14 year prospective evaluation of 1017 consecutive starts

2001 • 293 citations

The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus.

1988 • 270 citations

Effects of quinidine and related compounds on cytotoxicity and cellular accumulation of vincristine and adriamycin in drug-resistant tumor cells.

1984 • 231 citations

The direct activation of human multidrug resistance gene (MDR1) by anticancer agents

1989 • 223 citations

Multidrug resistance (mdr) genes in human cancer

1991 • 209 citations

Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals

1993 • 171 citations

Long-term treatment of rheumatoid arthritis with sulphasalazine, gold, or penicillamine: a comparison using life-table methods.

1987 • 137 citations

Isolation and characterization of Drosophila multidrug resistance gene homologs.

1991 • 118 citations

Expression of an mdr gene is associated with a new form of resistance to dexamethasone-induced apoptosis.

1993 • 116 citations

Methotrexate therapy in rheumatoid arthritis: a life table review of 587 patients treated in community practice.

1993 • 89 citations

Modulation of multidrug resistance gene expression by dexamethasone in cultured hepatoma cells.

1993 • 84 citations

Apparent stronger expression in the human adrenal cortex than in the human adrenal medulla of Mr 170,000-180,000 P-glycoprotein.

1988 • 61 citations

An overview of membrane, cytosolic and nuclear proteins associated with the expression of resistance to multiple drugs in vitro

1992 • 58 citations