Amplification of a Gene Related to Mammalian mdr Genes in Drug-Resistant Plasmodium falciparum

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

1987 • 2,266 citations

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

1986 • 1,903 citations

Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes

1986 • 1,863 citations

Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins

1986 • 1,058 citations

Structure of the Gene Encoding the Immunodominant Surface Antigen on the Sporozoite of the Human Malaria Parasite Plasmodium falciparum

1984 • 716 citations

Reversal of Chloroquine Resistance in Plasmodium falciparum by Verapamil

1987 • 558 citations

Efflux of Chloroquine from Plasmodium falciparum : Mechanism of Chloroquine Resistance

1987 • 523 citations

Isolation and genetic characterization of human KB cell lines resistant to multiple drugs

1985 • 517 citations

Reversal of Adriamycin Resistance by Verapamil in Human Ovarian Cancer

1984 • 398 citations

Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling.

1986 • 342 citations

The human mdr3 gene encodes a novel P-glycoprotein homologue and gives rise to alternatively spliced mRNAs in liver.

1987 • 283 citations

Cloning and characterization of a second member of the mouse mdr gene family.

1988 • 268 citations

Size variation in chromosomes from independent cultured isolates of Plasmodium falciparum

1985 • 201 citations

Verapamil Restoration of Daunorubicin Responsiveness in Daunorubicin-resistant Ehrlich Ascites Carcinoma

1982 • 157 citations

Plasmodium falciparum: Induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro

1988 • 140 citations

Codon usage in Plasmodium falciparum

1988 • 134 citations

Molecular karyotype of Plasmodium falciparum: conserved linkage groups and expendable histidine-rich protein genes.

1987 • 128 citations

Isolation of the Gene for a Glycophorin-Binding Protein Implicated in Erythrocyte Invasion by a Malaria Parasite

1985 • 89 citations

The problem of drug resistance in malaria

1985 • 82 citations

Unresolved issues in combination chemotherapy.

1986 • 39 citations

Chloroquine-Resistant Plasmodium falciparum: Difference in the Handling of ¹⁴ C-Amodiaquin and ¹⁴ C-Chloroquine

1973 • 35 citations

Plasmodium falciparum: Analysis of karyotype polymorphism using chromosome-specific probes

1988 • 10 citations