Sphingosine‐1‐phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro

Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.

1977 • 2,105 citations

XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors.

1998 • 867 citations

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1‐phosphate

1998 • 516 citations

An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors.

1990 • 474 citations

Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival

1998 • 468 citations

Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum

1997 • 442 citations

Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets

1995 • 435 citations

Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway

1998 • 404 citations

Intracellular Calcium Release Mediated by Sphingosine Derivatives Generated in Cells

1990 • 391 citations

Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1

2000 • 291 citations

Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction.

1995 • 264 citations

Differential Pharmacological Properties and Signal Transduction of the Sphingosine 1-Phosphate Receptors EDG-1, EDG-3, and EDG-5

1999 • 255 citations

Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium.

1994 • 253 citations

Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1

1998 • 252 citations

Identification of cDNAs encoding two G protein‐coupled receptors for lysosphingolipids¹

1997 • 247 citations

Sphingolipid metabolites: Members of a new class of lipid second messengers

1995 • 226 citations

Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors

1998 • 208 citations

Activation of a High Affinity Gi Protein-coupled Plasma Membrane Receptor by Sphingosine-1-phosphate

1996 • 197 citations

Ligand-induced Trafficking of the Sphingosine-1-phosphate Receptor EDG-1

1999 • 180 citations

EDG3 Is a Functional Receptor Specific for Sphingosine 1-Phosphate and Sphingosylphosphorylcholine with Signaling Characteristics Distinct from EDG1 and AGR16

1999 • 176 citations

Discussion

1999 • 154 citations

Molecular Cloning of a Novel Putative G Protein-Coupled Receptor Expressed in the Cardiovascular System

1993 • 150 citations

Lipid biochemistry: functions of glycerolipids and sphingolipids in cellular signaling

1997 • 136 citations

A novel membrane receptor with high affinity for lysosphingomyelin and sphingosine 1-phosphate in atrial myocytes.

1996 • 123 citations

Transduction of intracellular calcium signals through G protein-mediated activation of phospholipase C by recombinant sphingosine 1-phosphate receptors.

1999 • 123 citations

Molecular diversity of sphingolipid signalling

1997 • 108 citations

Sphingosine‐1‐phosphate reduces rat renal and mesenteric blood flow in vivo in a pertussis toxin‐sensitive manner

2000 • 84 citations

Calcium signalling by G protein-coupled sphingolipid receptors in bovine aortic endothelial cells

1996 • 58 citations

Ceramide: A Novel Cell Signaling Mechanism for Vasodilation

1997 • 42 citations

Effects of noradrenaline and neuropeptide Y on rat mesenteric microvessel contraction

1996 • 42 citations

Effect of sphingosine derivatives on calcium fluxes in thyroid FRTL-5 cells

1994 • 33 citations

Discrimination between plasma membrane and intracellular target sites of sphingosylphosphorylcholine

1998 • 32 citations

N‐Acetyl‐sphingenine‐1‐phosphate is a potent calcium mobilizing agent

1999 • 26 citations

Vasoconstriction of rat renal interlobar arteries by noradrenaline and neuropeptide Y

1997 • 23 citations

Intracellular calcium mobilization and phospholipid degradation in sphingosylphosphorylcholine-stimulated human airway epithelial cells

1998 • 20 citations

Expression and Activity of the Na<sup>+</sup>/H<sup>+</sup> Exchanger NHE-1 in Various Tissues of Spontaneously Hypertensive Rats and Normotensive Wistar-Kyoto Rats

1995 • 6 citations