A novel membrane receptor with high affinity for lysosphingomyelin and sphingosine 1-phosphate in atrial myocytes.

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

MODEL SYSTEMS FOR THE STUDY OF SEVEN-TRANSMEMBRANE-SEGMENT RECEPTORS

1991 • 1,357 citations

The sphingomyelin cycle and the second messenger function of ceramide.

1994 • 1,255 citations

The G-protein-gated atrial K+ channel IKAch is a heteromultimer of two inwardly rectifying K+-channel proteins

1995 • 830 citations

Ceramide: an intracellular signal for apoptosis

1995 • 604 citations

Lysosphingolipids Inhibit Protein Kinase C: Implications for the Sphingolipidoses

1987 • 593 citations

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

1994 • 583 citations

Phospholipid signaling

1995 • 561 citations

Methods for methanolysis of sphingolipids and direct determination of long‐chain bases by gas chromatography

1965 • 533 citations

Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel

1994 • 450 citations

Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets

1995 • 435 citations

Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor.

1996 • 280 citations

On the chemistry and occurrence of sphingolipid long-chain bases

1970 • 271 citations

Neurotrophins Induce Sphingomyelin Hydrolysis

1995 • 245 citations

Ceramide: A stress signal and mediator of growth suppression and apoptosis

1995 • 233 citations

Sphingolipid metabolites: Members of a new class of lipid second messengers

1995 • 226 citations

Activation of a High Affinity Gi Protein-coupled Plasma Membrane Receptor by Sphingosine-1-phosphate

1996 • 197 citations

Ceramide: an endogenous regulator of apoptosis and growth suppresion

1995 • 181 citations

Sphingosine 1-Phosphate Rapidly Activates the Mitogen-activated Protein Kinase Pathway by a G Protein-dependent Mechanism

1995 • 180 citations

Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells.

1993 • 179 citations

Involvement of a Pertussis Toxin-sensitive G Protein in the Mitogenic Signaling Pathways of Sphingosine 1-Phosphate

1995 • 161 citations

Direct G Protein Activation of Ion Channels?

1994 • 127 citations

Signaling pathways for sphingosylphosphorylcholine-mediated mitogenesis in Swiss 3T3 fibroblasts.

1993 • 117 citations

Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis

1995 • 113 citations

Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines

1991 • 109 citations

Preparation and characterization of well defined d-erythro sphingomyelins

1984 • 109 citations

Activation of muscarinic K+ current in guinea‐pig atrial myocytes by sphingosine‐1‐phosphate.

1995 • 106 citations

Sphingosylphosphorylcholine Rapidly Induces Tyrosine Phosphorylation of p125 and Paxillin, Rearrangement of the Actin Cytoskeleton and Focal Contact Assembly

1995 • 103 citations

Stereospecific activity of 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine and comparison of analogs in the degranulation of platelets and neutrophils

1981 • 95 citations

Role of cytoplasmic tail phosphorylation sites of platelet-activating factor receptor in agonist-induced desensitization.

1994 • 80 citations

Stereospecificity of sphingosine-induced intracellular calcium mobilization and cellular proliferation.

1994 • 76 citations

C-terminal Truncation of the Neurokinin-2 Receptor Causes Enhanced and Sustained Agonist-induced Signaling

1995 • 76 citations

Sphingosylphosphorylcholine Activation of Mitogen-activated Protein Kinase in Swiss 3T3 Cells Requires Protein Kinase C and a Pertussis Toxin-sensitive G Protein

1995 • 75 citations

Pertussis Toxin Inhibits Phospholipase C Activation and Ca2+ Mobilization by Sphingosylphosphorylcholine and Galactosylsphingosine in HL60 Leukemia Cells

1995 • 73 citations

The novel second messenger ceramide: identification, mechanism of action, and cellular activity.

1993 • 56 citations

Xenopus oocytes express multiple receptors for LPA-like lipid mediators

1996 • 55 citations

G-protein control of cardiac potassium channels

1994 • 25 citations

Activation of muscarinic K+ current in guinea‐pig atrial myocytes by a serum factor.

1993 • 16 citations

Modulation of cytosolic protein phosphorylation by sphingosylphosphorylcholine

1994 • 15 citations

Serum contains a potent factor that decreases ?-adrenergic receptor-stimulated L-type Ca2+ current in cardiac myocytes

1993 • 10 citations

Direct G Protein Activation of Ion Channels?

1994 • 8 citations