Intracellular Calcium Release Mediated by Sphingosine Derivatives Generated in Cells

Microdetermination of Phosphorus

1956 • 7,242 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects

1987 • 2,237 citations

ARACHIDONIC ACID METABOLISM

1986 • 1,802 citations

Functions of Sphingolipids and Sphingolipid Breakdown Products in Cellular Regulation

1989 • 1,251 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400

1989 • 1,039 citations

Lysosphingolipids Inhibit Protein Kinase C: Implications for the Sphingolipidoses

1987 • 593 citations

Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor

1989 • 531 citations

Purified inositol 1,4,5-trisphosphate receptor mediates calcium flux in reconstituted lipid vesicles

1989 • 512 citations

Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin.

1988 • 427 citations

Quantitation of free sphingosine in liver by high-performance liquid chromatography

1988 • 315 citations

Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases.

1986 • 307 citations

Modulation of protein kinase C and diverse cell functions by sphingosine — a pharmacologically interesting compound linking sphingolipids and signal transduction

1989 • 281 citations

Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds

1989 • 247 citations

Microsomal membrane permeability and the hepatic glucose-6-phosphatase system. Interactions of the system with D-mannose 6-phosphate and D-mannose.

1976 • 217 citations

Sphingosine inhibits calmodulin-dependent enzymes.

1988 • 215 citations

GTP-activated communication between distinct inositol 1,4,5-trisphosphate-sensitive and -insensitive calcium pools

1989 • 202 citations

Ca2+ release from endoplasmic reticulum is mediated by a guanine nucleotide regulatory mechanism

1986 • 175 citations

Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways.

1987 • 156 citations

Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells.

1988 • 151 citations

Influence of inositol 1,4,5-trisphosphate and guanine nucleotides on intracellular calcium release within the N1E-115 neuronal cell line.

1986 • 146 citations

Inositol 1,4,5-trisphosphate and guanine nucleotides activate calcium release from endoplasmic reticulum via distinct mechanisms.

1986 • 140 citations

Free Sphingosine Formation from Endogenous Substrates by a Liver Plasma Membrane System with a Divalent Cation Dependence and a Neutral pH Optimum

1989 • 102 citations

Intracellular calcium uptake activated by GTP. Evidence for a possible guanine nucleotide-induced transmembrane conveyance of intracellular calcium.

1987 • 99 citations

Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors.

1988 • 97 citations

GTP- and inositol 1,4,5-trisphosphate-activated intracellular calcium movements in neuronal and smooth muscle cell lines.

1987 • 94 citations

Androgen receptors in a Syrian hamster ductus deferens tumour cell line

1974 • 89 citations

Sphingomyelinase action inhibits phorbol ester-induced differentiation of human promyelocytic leukemic (HL-60) cells

1989 • 81 citations

Calcium entry into the inositol 1,4,5-trisphosphate-releasable calcium pool is mediated by a GTP-regulatory mechanism.

1988 • 78 citations

An intracellular (ATP + Mg2+)-dependent calcium pump within the N1E-115 neuronal cell line.

1985 • 76 citations

Calcium signalling mechanisms in endoplasmic reticulum activated by inositol 1,4,5-trisphosphate and GTP

1989 • 73 citations

Sphingolipid base metabolism. Partial purification and properties of sphinganine kinase of brain.

1976 • 68 citations

Sphingosine Kinase in Blood Platelets

1973 • 66 citations

Properties and Specificities of Sphingosine Kinase from Blood Platelets

1973 • 58 citations

Metabolism of Sphingosine Bases, XIII. Enzymatic Synthesis of 1-Phosphate Esters of 4t-Sphingenine (Sphingosine), Sphinganine (Dihydrosphingosine), 4-Hydroxysphinganine (Phytosphingosine) and 3-Dehydrosphinganine by Erythrocytes

1970 • 57 citations

Metabolism of Sphingosine Bases, XI. Distribution and Properties of Dihydrosphingosine-1-phosphate Aldolase (Sphinganine-1-phosphate alkanal-lyase)

1969 • 57 citations

A facile enzymatic synthesis of sphingosine-1-phosphate and dihydrosphingosine-1-phosphate.

1989 • 55 citations

Receptor kinships revealed

1989 • 53 citations

The Metabolism of Sphingosine Bases in Tetrahymena pyriformis. Sphingosine Kinase and Sphingosine-1-phosphate Lyase

1974 • 41 citations

The enzymatic phosphorylation of sphinganine

1969 • 32 citations