Relationship of Acute Lung Inflammatory Injury to Fas/FasL System

The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.

1994 • 6,682 citations

ACUTE RESPIRATORY DISTRESS IN ADULTS

1967 • 4,096 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Lpr and gld: Single Gene Models of Systemic Autoimmunity and Lymphoproliferative Disease

1991 • 1,185 citations

Macrophages and Polymorphonuclear Neutrophils in Lung Defense and Injury

1990 • 1,091 citations

Clinical risks for development of the acute respiratory distress syndrome.

1995 • 884 citations

Fas Ligand-Induced Apoptosis

1999 • 778 citations

Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.

1996 • 574 citations

Upregulation of Gelatinases A and B, Collagenases 1 and 2, and Increased Parenchymal Cell Death in COPD

2000 • 508 citations

Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C

1994 • 363 citations

Soluble Fas Ligand Induces Epithelial Cell Apoptosis in Humans with Acute Lung Injury (ARDS)

1999 • 358 citations

Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis

1999 • 344 citations

Incidence of acute lung injury in the United States*

2003 • 329 citations

In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13.

1997 • 300 citations

Fas/FasL-dependent Apoptosis of Alveolar Cells after Lipopolysaccharide-induced Lung Injury in Mice

2001 • 297 citations

Induction of Apoptosis and Pulmonary Fibrosis in Mice in Response to Ligation of Fas Antigen

1997 • 289 citations

Efficacy of Low Tidal Volume Ventilation in Patients with Different Clinical Risk Factors for Acute Lung Injury and the Acute Respiratory Distress Syndrome

2001 • 287 citations

Fas and Fas Ligand Are Up-Regulated in Pulmonary Edema Fluid and Lung Tissue of Patients with Acute Lung Injury and the Acute Respiratory Distress Syndrome

2002 • 286 citations

Ashbaugh DG, Bigelow DB, Petty TL, Levine BE. Acute respiratory distress in adults. The Lancet, Saturday 12 August 1967.

2005 • 251 citations

CD95/CD95 Ligand Interactions on Epithelial Cells in Host Defense to Pseudomonas aeruginosa

2000 • 251 citations

Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen.

1995 • 248 citations

The acute respiratory distress syndrome: Definitions, severity and clinical outcome An analysis of 101 clinical investigations

1996 • 246 citations

Fas (CD95) Induces Alveolar Epithelial Cell Apoptosis in Vivo

2001 • 240 citations

Acute Immunologic Pulmonary Alveolitis

1974 • 235 citations

Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells

2000 • 200 citations

Requirement for C-X-C chemokines (macrophage inflammatory protein-2 and cytokine-induced neutrophil chemoattractant) in IgG immune complex-induced lung injury.

1997 • 176 citations

Fas (CD95) Induces Proinflammatory Cytokine Responses by Human Monocytes and Monocyte-Derived Macrophages

2003 • 176 citations

Upregulation of Two Death Pathways of Perforin/Granzyme and FasL/Fas in Septic Acute Respiratory Distress Syndrome

2000 • 168 citations

The Involvement of Fas–Fas Ligand Pathway in Fibrosing Lung Diseases

1999 • 167 citations

Role of Complement, Chemokines, & Regulatory Cytokines in Acute Lung Injury

1996 • 152 citations

CD95 (Fas/Apo-1) as a Receptor Governing Astrocyte Apoptotic or Inflammatory Responses: A Key Role in Brain Inflammation?

1999 • 149 citations

Mediators and regulation of neutrophil accumulation in inflammatory responses in lung: insights from the IgG immune complex model 1,2 1This article is part of a series of reviews on “Reactive Oxygen and Nitrogen in Inflammation.” The full list of papers may be found on the homepage of the journal. 2Guest Editor: Giuseppe Poli

2002 • 148 citations

Fas Ligand Engagement of Resident Peritoneal Macrophages In Vivo Induces Apoptosis and the Production of Neutrophil Chemotactic Factors

2001 • 146 citations

The role of cytokines and adhesion molecules in the development of inflammatory injury

1995 • 135 citations

Improved prognosis of acute respiratory distress syndrome 15 years on

1999 • 124 citations

Intratracheal Instillation of Lipopolysaccharide in Mice Induces Apoptosis in Bronchial Epithelial Cells

2001 • 119 citations

Caspase-1-Deficient Mice Have Delayed Neutrophil Apoptosis and a Prolonged Inflammatory Response to Lipopolysaccharide-Induced Acute Lung Injury

2002 • 108 citations

Affinity labeling displays the stepwise activation of ICE-related proteases by Fas, staurosporine, and CrmA-sensitive caspase-8

1997 • 107 citations

Induction of Interleukin-8 Secretion and Apoptosis in Bronchiolar Epithelial Cells by Fas Ligation

1999 • 104 citations

Apoptosis in lung pathophysiology

2000 • 97 citations

Fas expression in pulmonary alveolar type II cells

1997 • 92 citations

Evidence for the involvement of Fas ligand and perforin in the induction of vascular leak syndrome.

1998 • 69 citations

Fas-Mediated Stimulation Induces IL-8 Secretion by Rheumatoid Arthritis Synoviocytes Independently of CPP32-Mediated Apoptosis

1996 • 65 citations

Evidence for the Involvement of Fas Ligand and Perforin in the Induction of Vascular Leak Syndrome

1998 • 63 citations

Regulation of Fas (CD95)-induced apoptosis by nuclear factor-κB and tumor necrosis factor-α in macrophages

2002 • 40 citations

Neutrophil Modulation of the Pulmonary Chemokine Response to Lipopolysaccharide

2002 • 30 citations

Adult Respiratory Distress Syndrome

1992 • 15 citations

Deleted Work

1955 • 0 citations