Regulation of Fas (CD95)-induced apoptosis by nuclear factor-κB and tumor necrosis factor-α in macrophages

Apoptosis by Death Factor

1997 • 5,038 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

The Fas Death Factor

1995 • 4,070 citations

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1998 • 3,169 citations

Activators and Target Genes of Rel/NF-кB Transcription Factors

2003 • 3,164 citations

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

1998 • 2,698 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1995 • 1,849 citations

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1998 • 1,651 citations

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 • 1,524 citations

Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1995 • 1,477 citations

Lpr and gld: Single Gene Models of Systemic Autoimmunity and Lymphoproliferative Disease

1991 • 1,185 citations

The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene

1999 • 978 citations

Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B.

1990 • 900 citations

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control

1997 • 875 citations

The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen.

1992 • 839 citations

Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase

1999 • 827 citations

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.

1994 • 723 citations

Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice.

2000 • 523 citations

Fas transduces activation signals in normal human T lymphocytes.

1993 • 521 citations

The Role of Fas in Autoimmune Diabetes

1997 • 503 citations

Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice

2000 • 469 citations

Lipopolysaccharide Induction of the Tumor Necrosis Factor-α Promoter in Human Monocytic Cells

1997 • 466 citations

IEX -1L, an Apoptosis Inhibitor Involved in NF-κB-Mediated Cell Survival

1998 • 417 citations

Female Mice Heterozygous for IKKγ/NEMO Deficiencies Develop a Dermatopathy Similar to the Human X-Linked Disorder Incontinentia Pigmenti

2000 • 395 citations

Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells.

1993 • 341 citations

A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease.

1992 • 310 citations

Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death.

1994 • 304 citations

Regulation of Fas-Ligand Expression during Activation-induced Cell Death in T Lymphocytes via Nuclear Factor κB

1999 • 257 citations

Fas mediates apoptosis in human monocytes by a reactive oxygen intermediate dependent pathway.

1996 • 228 citations

Inhibition of Nuclear Factor κB Activation Attenuates Apoptosis Resistance in Lymphoid Cells

1998 • 225 citations

A Critical Role for the RelA Subunit of Nuclear Factor κB in Regulation of Multiple Immune-response Genes and in Fas-induced Cell Death

1999 • 147 citations

Apoptosis and nuclear factor-κb: a tale of association and dissociation

2000 • 146 citations

The CD95 (APO-1/Fas) Receptor Activates NF- B Independently of Its Cytotoxic Function

1996 • 146 citations

CD95 (Fas)-induced caspase-mediated proteolysis of NF-kappaB.

1998 • 123 citations

No requirement of reactive oxygen intermediates in Fas‐mediated apoptosis

1994 • 107 citations

NF-κB regulates Fas / APO-1 / CD95- and TCR-mediated apoptosis of T lymphocytes

1999 • 87 citations

Fas/Apo-1 activates nuclear factor kappa B and induces interleukin-6 production.

1995 • 77 citations

Fas‐induced programmed cell death is mediated by a Ras‐regulated O₂⁻ synthesis

1996 • 75 citations

Thiol-mediated inhibition of FAS and CD2 apoptotic signaling in activated human peripheral T cells

1997 • 73 citations

Tumor necrosis factor α prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: Role of nuclear factor-κB

2000 • 70 citations

A molecular genetic linkage map of mouse chromosome 19, including thelpr, Ly-44, andTdt genes

1991 • 68 citations

Segregation of APO‐1/Fas antigen‐ and tumor necrosis factor receptor‐mediated apoptosis

1994 • 46 citations

Dual mechanism of Fas-induced cell death in neuroglioma cells: a role for reactive oxygen species

1999 • 44 citations

The Fas Pathway in Apoptosis

1997 • 29 citations

Apoptosis, proliferation and NF‐κB activation induced by agonistic Fas antibodies in the human myeloma cell line OH‐2: amplification of Fas‐mediated apoptosis by tumor necrosis factor

1999 • 25 citations