Induction of Interleukin-8 Secretion and Apoptosis in Bronchiolar Epithelial Cells by Fas Ligation

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways

1996 • 1,976 citations

MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

1997 • 1,294 citations

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

1993 • 1,144 citations

The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

1989 • 1,060 citations

TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40

1995 • 1,046 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung.

1990 • 678 citations

Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF

1989 • 602 citations

Interleukin-8 (IL-8): The Major Neutrophil Chemotactic Factor in the Lung

1991 • 550 citations

RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis.

1996 • 540 citations

Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome.

1996 • 517 citations

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

1997 • 453 citations

Transgenic expression of CD95 ligand on islet β cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts

1997 • 373 citations

Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes.

1995 • 368 citations

Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C

1994 • 363 citations

Antitumor effect of locally produced CD95 ligand

1997 • 315 citations

Induction of Apoptosis and Pulmonary Fibrosis in Mice in Response to Ligation of Fas Antigen

1997 • 289 citations

Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice.

1997 • 274 citations

Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis.

1991 • 249 citations

Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen.

1995 • 248 citations

Elevated IL-8 and MCP-1 in the bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis.

1994 • 248 citations

Interactions between neutrophils and cytokines in blood and alveolar spaces during ARDS.

1996 • 235 citations

A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells.

1996 • 229 citations

Bronchoalveolar and systemic cytokine profiles in patients with ARDS, severe pneumonia and cardiogenic pulmonary oedema

1996 • 222 citations

Interleukin-8 delays spontaneous and tumor necrosis factor-α-mediated apoptosis of human neutrophils

1998 • 209 citations

Interleukin-8 and Related Chemotactic Cytokines

1994 • 189 citations

Expression of Fas Antigen on Keratinocytes In Vivo and Induction of Apoptosis in Cultured Keratinocytes

1994 • 175 citations

Expression and Release of Interleukin-8 by Human Airway Smooth Muscle Cells: Inhibition by Th-2 Cytokines and Corticosteroids

1998 • 171 citations

A Promoter Recruitment Mechanism for Tumor Necrosis Factor-α-induced Interleukin-8 Transcription in Type II Pulmonary Epithelial Cells

1998 • 170 citations

The Involvement of Fas–Fas Ligand Pathway in Fibrosing Lung Diseases

1999 • 167 citations

Dexamethasone inhibits lung epithelial cell apoptosis induced by IFN-γ and Fas

1997 • 148 citations

The CD95 (APO-1/Fas) Receptor Activates NF- B Independently of Its Cytotoxic Function

1996 • 146 citations

Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions.

1994 • 143 citations

Changes in the inflammatory response of the lung during acute respiratory distress syndrome: prognostic indicators.

1996 • 139 citations

Monitoring early cellular responses in apoptosis is aided by the mitochondrial membrane protein-specific monoclonal antibody APO2.7

1997 • 105 citations

Fas expression in pulmonary alveolar type II cells

1997 • 92 citations

Tumor necrosis factor-induced interleukin-8 expression in cultured human airway epithelial cells

1994 • 81 citations

Fas (CD95/Apo-1)–Mediated Damage to Ventricular Myocytes Induced by Cytotoxic T Lymphocytes From Perforin-Deficient Mice

1998 • 79 citations

Cell-matrix and cell-cell interactions modulate apoptosis of bronchial epithelial cells

1997 • 73 citations

Flow cytometric assessment of three different methods for the measurement of in vitro apoptosis

1998 • 60 citations

Wild-type p53 induces apoptosis in Hep3B through up-regulation of bax expression.

1997 • 30 citations