The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the TargetedN-Sulfoglucosamine

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Proteoglycans: Structures And Interactions

1991 • 1,596 citations

Biology of the Syndecans: A Family of Transmembrane Heparan Sulfate Proteoglycans

1992 • 1,095 citations

Initial interaction of herpes simplex virus with cells is binding to heparan sulfate

1989 • 913 citations

Formation of anhydrosugars in the chemical depolymerization of heparin

1976 • 903 citations

T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ

1993 • 896 citations

A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane.

1988 • 892 citations

Heparin Structure and Interactions with Basic Fibroblast Growth Factor

1996 • 789 citations

Regulated Diversity of Heparan Sulfate

1998 • 671 citations

Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.

1993 • 542 citations

Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

1994 • 541 citations

An Essential Heparin-Binding Domain in the Fibroblast Growth Factor Receptor Kinase

1993 • 520 citations

Heparin-Binding Proteins

1998 • 515 citations

Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.

1992 • 511 citations

Microbial adherence to and invasion through proteoglycans

1997 • 480 citations

Cell surface heparan sulfate proteoglycans.

1992 • 476 citations

Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

1999 • 474 citations

Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase

1998 • 453 citations

Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor.

1993 • 449 citations

The Putative Tumor Suppressors EXT1 and EXT2 Are Glycosyltransferases Required for the Biosynthesis of Heparan Sulfate

1998 • 425 citations

Integral membrane heparan sulfate proteoglycans

1993 • 423 citations

Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan

1993 • 420 citations

Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated?

1997 • 392 citations

The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

1998 • 377 citations

The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer.

1998 • 355 citations

Structure of a heparin-linked biologically active dimer of fibroblast growth factor

1998 • 350 citations

Extension and structural variability of the antithrombin-binding sequence in heparin.

1984 • 340 citations

Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2

1998 • 339 citations

Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants

1994 • 316 citations

The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis

1997 • 290 citations

Domain Structure of Heparan Sulfates from Bovine Organs

1996 • 281 citations

Heparan Sulfate Oligosaccharides Require 6-O-Sulfation for Promotion of Basic Fibroblast Growth Factor Mitogenic Activity

1998 • 276 citations

Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling

1997 • 257 citations

dally, a Drosophila glypican, controls cellular responses to the TGF-β-related morphogen, Dpp

1997 • 241 citations

Multiple Isoforms of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase

1999 • 237 citations

Spatially Restricted Expression of pipe in the Drosophila Egg Chamber Defines Embryonic Dorsal–Ventral Polarity

1998 • 208 citations

Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila

1997 • 196 citations

Expression of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase Isoforms Reveals Novel Substrate Specificities

1999 • 180 citations

Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor

1992 • 173 citations

Heparan Sulfate Proteoglycans as Adhesive and Anti-invasive Molecules

1998 • 163 citations

Molecular cloning and expression of rat liver N-heparan sulfate sulfotransferase.

1992 • 163 citations

Molecular Cloning and Expression of a Third Member of the Heparan Sulfate/Heparin GlcNAcN-Deacetylase/N-Sulfotransferase Family

1999 • 161 citations

Molecular Cloning and Expression of Mouse and Human cDNAs Encoding Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase

1997 • 159 citations

Molecular cloning and expression of a glycosaminoglycan N-acetylglucosaminyl N-deacetylase/N-sulfotransferase from a heparin-producing cell line.

1994 • 152 citations

cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin.

1994 • 151 citations

Molecular Cloning and Characterization of Human Keratan Sulfate Gal-6-Sulfotransferase

1997 • 147 citations

Preparation of affinity-fractionated, heparin-derived oligosaccharides and their effects on selected biological activities mediated by basic fibroblast growth factor.

1993 • 138 citations

An Animal Cell Mutant Defective in Heparan Sulfate Hexuronic Acid 2- -Sulfation

1996 • 132 citations

The coordinated regulation of heparan sulfate, syndecans and cell behavior

1993 • 129 citations

Molecular Cloning and Expression of Chick Chondrocyte Chondroitin 6-Sulfotransferase

1995 • 125 citations

Heparan Sulfate Undergoes Specific Structural Changes during the Progression from Human Colon Adenoma to Carcinoma in Vitro

1998 • 125 citations

Molecular Cloning and Expression of Chinese Hamster Ovary Cell Heparan-sulfate 2-Sulfotransferase

1997 • 122 citations

Structure of heparan sulphate from human brain, with special regard to Alzheimer's disease

1995 • 117 citations

Purification of Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase

1996 • 115 citations

The Role of Syndecan-1 in Malignancies

1996 • 114 citations

Characterization of Heparan Sulfate Oligosaccharides That Bind to Hepatocyte Growth Factor

1995 • 114 citations

Molecular Characterization and Expression of Heparan-sulfate 6-Sulfotransferase

1998 • 101 citations

Biosynthesis of heparin. Purification of a 110-kDa mouse mastocytoma protein required for both glucosaminyl N-deacetylation and N-sulfation

1991 • 92 citations

Biosynthesis of heparin/heparan sulfate. Identification of a 70-kDa protein catalyzing both the D-glucuronosyl- and the N-acetyl-D-glucosaminyltransferase reactions.

1993 • 88 citations

Purification and Characterization of Heparan Sulfate 6-Sulfotransferase from the Culture Medium of Chinese Hamster Ovary Cells

1995 • 87 citations

Identification and Expression in Mouse of Two Heparan Sulfate Glucosaminyl N-Deacetylase/N-Sulfotransferase Genes

1998 • 85 citations

Purification of rat liver N-heparan-sulfate sulfotransferase.

1988 • 78 citations

Purification and Characterization of Heparan Sulfate 2-Sulfotransferase from Cultured Chinese Hamster Ovary Cells

1996 • 75 citations

Amyloid-specific Heparan Sulfate from Human Liver and Spleen

1997 • 73 citations

A role of Lys⁶¹⁴ in the sulfotransferase activity of human heparan sulfate N‐deacetylase/N‐sulfotransferase

1998 • 55 citations

A monoclonal antibody directed to terminal residue of β-galactofuranose of a glycolipid antigen isolated from Paracoccidioides brasiliensis: cross-reactivity with Leishmania major and Trypanosoma cruzi

1997 • 55 citations

Regulation of biosynthesis of the basic fibroblast growth factor binding domains of heparan sulfate by heparan sulfate-N-deacetylase/N-sulfotransferase expression.

1993 • 54 citations

Expression of the Mouse Mastocytoma Glucosaminyl N-Deacetylase/N-Sulfotransferase in Human Kidney 293 Cells Results in Increased N-Sulfation of Heparan Sulfate

1996 • 51 citations

Biosynthesis of heparin/heparan sulfate. Purification of the D-glucuronyl C-5 epimerase from bovine liver.

1994 • 45 citations

Structural comparison of fibroblast growth factor-specific heparan sulfates derived from a growing or differentiating neuroepithelial cell line

1998 • 44 citations

Cell-free Synthesis of Anticoagulant Heparan Sulfate Reveals a Limiting Converting Activity That Modifies an Excess Precursor Pool

1996 • 40 citations

Preparation and high-performance liquid chromatography of 3′-phosphoadenosine-5′-phospho[35S]sulfate with a predetermined specific activity

1985 • 36 citations

The Retinoic Acid and cAMP-dependent Up-regulation of 3-O-Sulfotransferase-1 Leads to a Dramatic Augmentation of Anticoagulantly Active Heparan Sulfate Biosynthesis in F9 Embryonal Carcinoma Cells

1998 • 34 citations

Differentiation-associated modulation of heparan sulfate structure and function in CaCo-2 colon carcinoma cells

1998 • 32 citations

Biosynthesis of heparin. Enzymatic sulfation of pentasaccharides.

1991 • 26 citations