Expression of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase Isoforms Reveals Novel Substrate Specificities

Formation of anhydrosugars in the chemical depolymerization of heparin

1976 • 903 citations

Evidence for a 3-O-sulfated D-glucosamine residue in the antithrombin-binding sequence of heparin.

1980 • 489 citations

Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated?

1997 • 392 citations

Cloned bovine aortic endothelial cells synthesize anticoagulantly active heparan sulfate proteoglycan.

1986 • 342 citations

Correlation between structure and function of heparin

1979 • 277 citations

Biosynthesis of heparin

1986 • 245 citations

A monoclonal antibody against GBM heparan sulfate induces an acute selective proteinuria in rats

1992 • 237 citations

Multiple Isoforms of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase

1999 • 237 citations

Structural characterization of the oligosaccharides formed by depolymerization of heparin with nitrous acid.

1985 • 194 citations

Molecular cloning and expression of rat liver N-heparan sulfate sulfotransferase.

1992 • 163 citations

Molecular Cloning and Expression of Mouse and Human cDNAs Encoding Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase

1997 • 159 citations

Molecular cloning and expression of a glycosaminoglycan N-acetylglucosaminyl N-deacetylase/N-sulfotransferase from a heparin-producing cell line.

1994 • 152 citations

Synthesis of heparin fragments: A methyl α-pentaoside with high affinity for antithrombin III

1987 • 151 citations

cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin.

1994 • 151 citations

Heparan sulfate proteoglycan in the glomerular basement membrane in type 1 diabetes mellitus

1992 • 142 citations

Molecular Cloning and Expression of Chinese Hamster Ovary Cell Heparan-sulfate 2-Sulfotransferase

1997 • 122 citations

Structure of heparan sulphate from human brain, with special regard to Alzheimer's disease

1995 • 117 citations

Purification of Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase

1996 • 115 citations

Novel Sulfated Oligosaccharides Containing 3-O-Sulfated Glucuronic Acid from King Crab Cartilage Chondroitin Sulfate K

1996 • 99 citations

Structure and antithrombin-binding properties of heparin isolated from the clams Anomalocardia brasiliana and Tivela mactroides.

1987 • 99 citations

Biosynthesis of Heparin/Heparan Sulfate

1997 • 96 citations

Hydrazinolysis of heparin and other glycosaminoglycans

1984 • 95 citations

Characterization of ryudocan glycosaminoglycan acceptor sites.

1994 • 90 citations

Biosynthesis of heparin/heparan sulfate. Identification of a 70-kDa protein catalyzing both the D-glucuronosyl- and the N-acetyl-D-glucosaminyltransferase reactions.

1993 • 88 citations

Purification and Characterization of Heparan Sulfate 6-Sulfotransferase from the Culture Medium of Chinese Hamster Ovary Cells

1995 • 87 citations

Pathway-specific regulation of the synthesis of anticoagulantly active heparan sulfate.

1994 • 77 citations

Two N-acetylglucosaminyltransferases catalyze the biosynthesis of heparan sulfate.

1994 • 63 citations

Analysis of oligosaccharides from heparin by reversed-phase ion-pairing high-performance liquid chromatography

1988 • 62 citations

Human liver iduronate-2-sulphatase. Purification, characterization and catalytic properties

1990 • 59 citations

Search for the heparin antithrombin III-binding site precursor.

1992 • 59 citations

Characterization of novel sequences containing 3-O-sulfated glucosamine in glomerular basement membrane heparan sulfate and localization of sulfated disaccharides to a peripheral domain.

1990 • 58 citations

Biosynthesis of heparan sulfate. Coordination of polymer-modification reactions in a Chinese hamster ovary cell mutant defective in N-sulfotransferase

1991 • 56 citations

Basement-membrane heparan sulphate with high affinity for antithrombin synthesized by normal and transformed mouse mammary epithelial cells

1987 • 55 citations

Regulation of biosynthesis of the basic fibroblast growth factor binding domains of heparan sulfate by heparan sulfate-N-deacetylase/N-sulfotransferase expression.

1993 • 54 citations

Expression of the Mouse Mastocytoma Glucosaminyl N-Deacetylase/N-Sulfotransferase in Human Kidney 293 Cells Results in Increased N-Sulfation of Heparan Sulfate

1996 • 51 citations

Characterization of a cell mutant specifically defective in the synthesis of anticoagulantly active heparan sulfate.

1994 • 42 citations

Quantitation of the sulfated disaccharides of heparin by high performance liquid chromatography

1980 • 42 citations

Cell-free Synthesis of Anticoagulant Heparan Sulfate Reveals a Limiting Converting Activity That Modifies an Excess Precursor Pool

1996 • 40 citations

The Retinoic Acid and cAMP-dependent Up-regulation of 3-O-Sulfotransferase-1 Leads to a Dramatic Augmentation of Anticoagulantly Active Heparan Sulfate Biosynthesis in F9 Embryonal Carcinoma Cells

1998 • 34 citations

Evaluation of the Cell Specificity and Sulfate Dependence of Glomerular Extracellular Matrix Proteoglycan Synthesis

1995 • 8 citations