dally, a Drosophila glypican, controls cellular responses to the TGF-β-related morphogen, Dpp

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Betaglycan presents ligand to the TGFβ signaling receptor

1993 • 887 citations

Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome

1996 • 767 citations

Direct and Long-Range Action of a Wingless Morphogen Gradient

1996 • 736 citations

Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing

1996 • 629 citations

Induction of Drosophila eye development by Decapentaplegic

1997 • 567 citations

Requirement for BMP Signaling in Interdigital Apoptosis and Scale Formation

1996 • 552 citations

Autoproteolysis in hedgehog protein biogenesis

1994 • 541 citations

Integral membrane heparan sulfate proteoglycans

1993 • 423 citations

The astacin family of metalloendopeptidases

1995 • 388 citations

The wingless signalling pathway and the patterning of the wing margin in Drosophila

1994 • 354 citations

Decapentaplegic: A gene complex affecting morphogenesis in Drosophila melanogaster

1982 • 345 citations

Induction across germ layers in Drosophila mediated by a genetic cascade

1990 • 342 citations

An extensive 3′ cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-β family in Drosophila

1991 • 330 citations

Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs

1994 • 330 citations

Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila

1994 • 317 citations

An absolute requirement for both the type II and type I receptors, punt and thick veins, for Dpp signaling in vivo

1995 • 312 citations

Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction.

1996 • 307 citations

Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts.

1990 • 292 citations

The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1

1991 • 292 citations

An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo

1993 • 283 citations

Stimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypican.

1996 • 273 citations

Axis specification in the developing Drosophila appendage: The role of wingless, decapentaplegic, and the homeobox gene aristaless

1993 • 271 citations

The division abnormally delayed (dally) gene: a putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila

1995 • 271 citations

Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing

1996 • 264 citations

Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling

1997 • 257 citations

Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

1994 • 254 citations

Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements.

1990 • 250 citations

spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo.

1994 • 246 citations

Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis

1995 • 246 citations

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate.

1992 • 241 citations

Cell cycling and patterned cell proliferation in the wing primordium of Drosophila.

1996 • 231 citations

Control of the Gene optomotor-blind in Drosophila Wing Development by decapentaplegic and wingless

1996 • 206 citations

Signaling by wingless in Drosophila

1994 • 200 citations

Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila

1997 • 196 citations

Mobilization of hobo elements residing within the decapentaplegic gene complex: Suggestion of a new hybrid dysgenesis system in Drosophila melanogaster

1987 • 190 citations

Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation

1994 • 186 citations

Complementary and Mutually Exclusive Activities of Decapentaplegic and Wingless Organize Axial Patterning during Drosophila Leg Development

1996 • 178 citations

Sulfated Oligosaccharides Promote Hepatocyte Growth Factor Association and Govern Its Mitogenic Activity

1995 • 170 citations

K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney.

1995 • 147 citations

Role of decapentaplegic in initiation and progression of the morphogenetic furrow in the developing Drosophila retina

1997 • 147 citations

Cell cycling and patterned cell proliferation in the Drosophila wing during metamorphosis.

1996 • 143 citations

Developmental territories created by mutual antagonism between Wingless and Decapentaplegic

1996 • 139 citations

Inhibition of basic fibroblast growth factor-induced growth promotion by overexpression of syndecan-1.

1993 • 129 citations

Mammalian anti proliferative signals and their targets

1995 • 125 citations

Heparin-dependent binding and autophosphorylation of epidermal growth factor (EGF) receptor by heparin-binding EGF-like growth factor but not by EGF.

1994 • 122 citations

wingless refines its own expression domain on the Drosophila wing margin

1996 • 116 citations

Transforming Growth Factor β1 Induces Apoptotic Cell Death in Cultured Human Umbilical Vein Endothelial Cells with Down-Regulated Expression of BCL-2

1995 • 106 citations

Decapentaplegic restricts the domain of wingless during Drosophila limb patterning

1996 • 104 citations

Neuronal expression of glypican, a cell-surface glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan, in the adult rat nervous system

1994 • 97 citations

White as a reporter gene to detect transcriptional silencers specifying position-specific gene expression during Drosophila melanogaster eye development.

1995 • 91 citations

Regulation of Cell Cycle Synchronization by decapentaplegic During Drosophila Eye Development

1997 • 90 citations

Behind the Official Optimism, Flawed Projections

1996 • 89 citations

Both transforming growth factor-beta and substrate release are inducers of apoptosis in a human colon adenoma cell line.

1995 • 83 citations

Identification of a new membrane-bound heparan sulphate proteoglycan

1995 • 76 citations

SHAGGY and DISHEVELLED exert opposite effects on wingless and decapentaplegic expression and on positional identity in imaginal discs

1997 • 72 citations

decapentaplegic, a target gene of the wingless signalling pathway in the Drosophila midgut

1996 • 68 citations

Cloning of a major heparan sulfate proteoglycan from brain and identification as the rat form of glypican

1992 • 53 citations

Genetic and molecular characterization of the optomotor-blind gene locus in Drosophila melanogaster.

1990 • 50 citations

Transforming Growth Factor-β1 (TGFβ1) Enhances Apoptosis in Human Papillomavirus Type 16-Immortalized Human Ectocervical Epithelial Cells

1995 • 38 citations

Induction of a mirror-image duplication of anterior wing structures by localized hedgehog expression in the anterior compartment of Drosophila melanogaster wing imaginal discs

1994 • 28 citations

Regulation, function and potential origin of the Drosophila gene spalt adjacent, which encodes a secreted protein expressed in the early embryo

1996 • 20 citations

Heparin and its Derivatives Modulate Serine Proteinases (SERPS) Serine Proteinase Inhibitors (SERPINS) Balance

1994 • 17 citations