The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Proteoglycans: Structures And Interactions

1991 • 1,596 citations

A new member of the frizzled family from Drosophila functions as a Wingless receptor

1996 • 1,489 citations

A stable genomic source of P element transposase in Drosophila melanogaster.

1988 • 1,359 citations

Biology of the Syndecans: A Family of Transmembrane Heparan Sulfate Proteoglycans

1992 • 1,095 citations

Expression of engrailed proteins in arthropods, annelids, and chordates

1989 • 1,019 citations

Organizing activity of wingless protein in Drosophila

1993 • 852 citations

Wnt genes

1992 • 799 citations

Direct and Long-Range Action of a Wingless Morphogen Gradient

1996 • 736 citations

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation

1994 • 665 citations

The Autosomal FLP-DFS Technique for Generating Germline Mosaics in Drosophila melanogaster

1996 • 652 citations

Chapter 24 Imaging Neuronal Subsets and Other Cell Types in Whole-Mount Drosophila Embryos and Larvae Using Antibody Probes

1994 • 608 citations

Functional cDNA libraries from Drosophila embryos

1988 • 604 citations

The Drosophila smoothened Gene Encodes a Seven-Pass Membrane Protein, a Putative Receptor for the Hedgehog Signal

1996 • 591 citations

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

1992 • 585 citations

Insertional Mutagenesis of the Drosophila Genome with Single P Elements

1988 • 533 citations

Sequence, structure, and codon preference of theDrosophilaribosomal protein 49 gene

1984 • 523 citations

Regulation of growth factor activation by proteoglycans: What is the role of the low affinity receptors?

1995 • 478 citations

Cell surface heparan sulfate proteoglycans.

1992 • 476 citations

Gene disruptions using P transposable elements: an integral component of the Drosophila genome project.

1995 • 472 citations

Distribution of the wingless gene product in drosophila embryos: A protein involved in cell-cell communication

1989 • 452 citations

wingless signaling acts through zeste-white 3, the drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate

1992 • 425 citations

Integral membrane heparan sulfate proteoglycans

1993 • 423 citations

The alphas, betas, and kinases of cytokine receptor complexes

1993 • 418 citations

Role of the Drosophila patched gene in positional signalling

1991 • 414 citations

Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing

1995 • 392 citations

Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis

1988 • 383 citations

Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo

1988 • 381 citations

A Large Family of Putative Transmembrane Receptors Homologous to the Product of the Drosophila Tissue Polarity Gene frizzled

1996 • 369 citations

Chapter 33 Ectopic Expression in Drosophila

1994 • 360 citations

The wingless signalling pathway and the patterning of the wing margin in Drosophila

1994 • 354 citations

Information for the dorsal–ventral pattern of the Drosophila embryo is stored as maternal mRNA

1984 • 335 citations

Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips

1996 • 312 citations

Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction.

1996 • 307 citations

Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages.

1996 • 303 citations

heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo.

1996 • 298 citations

Roles of wingless in patterning the larval epidermis of Drosophila

1991 • 295 citations

Negative regulation of Armadillo, a Wingless effector in Drosophila

1997 • 285 citations

The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix.

1990 • 280 citations

The division abnormally delayed (dally) gene: a putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila

1995 • 271 citations

trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila.

1996 • 264 citations

Tubulogenesis in Drosophila: a requirement for the trachealess gene product.

1996 • 264 citations

Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein.

1993 • 254 citations

Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

1991 • 244 citations

Drosophila melanogaster. Practical uses in cell and molecular biology

1995 • 232 citations

Secreted int-1 protein is associated with the cell surface.

1990 • 215 citations

crumbs and stardust Act in a Genetic Pathway That Controls the Organization of Epithelia in Drosophila melanogaster

1993 • 210 citations

Signaling by wingless in Drosophila

1994 • 200 citations

Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. I. Loci on the X chromosome.

1989 • 200 citations

Homeotic genes and positional signalling in the Drosophila viscera

1994 • 180 citations

Zygotic Lethal Mutations With Maternal Effect Phenotypes in Drosophila melanogaster. II. Loci on the Second and Third Chromosomes Identified by P-Element-Induced Mutations

1996 • 174 citations

Dual functions of wingless in the Drosophila leg imaginal disc

1995 • 167 citations

drifter, a Drosophila POU-domain transcription factor, is required for correct differentiation and migration of tracheal cells and midline glia.

1995 • 164 citations

Drosophila wingless: A paradigm for the function and mechanism of Wnt signaling

1994 • 157 citations

Drosophila syndecan: conservation of a cell-surface heparan sulfate proteoglycan.

1994 • 148 citations

Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing

1995 • 145 citations

The Wnt family of developmental regulators

1992 • 121 citations

Biochemical Analysis of Murine Wnt Proteins Reveals both Shared and Distinct Properties

1995 • 96 citations

Evidence for engrailed-Independent wingless Autoregulation in Drosophila

1995 • 94 citations

The wingless product is required for cell proliferation in the Malpighian tubule anlage of Drosophila melanogaster

1992 • 78 citations

Serpentine Proteins Slither into the Wingless and Hedgehog Fields

1996 • 74 citations

UDP‐glucose dehydrogenase from bovine liver: Primary structure and relationship to other dehydrogenases

1994 • 60 citations

Invagination centers within the Drosophila stomatogastric nervous system anlage are positioned by Notch-mediated signaling which is spatially controlled through wingless

1995 • 59 citations

Drosophila wingless sustains engrailed expression only in adjoining cells: Evidence from mosaic embryos

1994 • 57 citations

The porcupine gene is required for wingless autoregulation in Drosophila

1995 • 33 citations