INFLAMMATORY CELL RECRUITMENT FOLLOWING THORACIC IRRADIATION

Idiopathic Pulmonary Fibrosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy

2001 • 1,727 citations

Respiratory effects are associated with the number of ultrafine particles.

1997 • 1,270 citations

A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis

1995 • 641 citations

TGF-β1 and radiation fibrosis: a master switch and a specific therapeutic target?

2000 • 626 citations

Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice.

1989 • 433 citations

Evidence of Fibroblast Heterogeneity and the Role of Fibroblast Subpopulations in Fibrosis

1994 • 343 citations

Pathobiology of pulmonary fibrosis

1990 • 326 citations

Radiation and the lung: A reevaluation of the mechanisms mediating pulmonary injury

1995 • 265 citations

Plasma transforming growth factor β1 as a predictor of radiation pneumonitis

1998 • 236 citations

Molecular biology mechanisms in the radiation induction of pulmonary injury syndromes: Interrelationship between the alveolar macrophage and the septal fibroblast

1992 • 216 citations

Radiation pneumonitis after breast cancer irradiation: analysis of the complication probability using the relative seriality model

2000 • 175 citations

Early and persistent alterations in the expression of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor alpha mRNA levels in fibrosis-resistant and sensitive mice after thoracic irradiation.

1996 • 175 citations

Radiation-Induced Pulmonary Fibrosis: Examination of Chemokine and Chemokine Receptor Families

2002 • 174 citations

Early and Persistent Alterations in the Expression of Interleukin-1α, Interleukin-1β and Tumor Necrosis Factor α mRNA Levels in Fibrosis-Resistant and Sensitive Mice after Thoracic Irradiation

1996 • 156 citations

The Effects of the Nude(nu/nu)Mutation on Bleomycin-induced Pulmonary Fibrosis

1983 • 145 citations

Molecular and cellular basis of radiation fibrosis

1998 • 144 citations

Novel roles for chemokines and fibroblasts in interstitial fibrosis

1998 • 130 citations

A Quantitative Histological Study of Strain-Dependent Differences in the Effects of Irradiation on Mouse Lung during the Intermediate and Late Phases

1989 • 130 citations

Immunohistochemical Localization of Transforming Growth Factor β and Tumor Necrosis Factor α in the Lungs of Fibrosis-Prone and "Non-Fibrosing" Mice during the Latent Period and Early Phase after Irradiation

1997 • 120 citations

The role of cytokines in the development of normal-tissue reactions after radiotherapy.

1998 • 117 citations

Epithelium–fibroblast interactions in response to airway inflammation

2001 • 112 citations

The development of bleomycin-induced pulmonary fibrosis in neutrophil-depleted and complement-depleted rats.

1981 • 107 citations

Regulation of immune response to inhaled antigen by alveolar macrophages: differential effects of in vivo alveolar macrophage elimination on the induction of tolerance vs. immunity

1991 • 105 citations

Differences in Correlation of mRNA Gene Expression in Mice Sensitive and Resistant to Radiation-Induced Pulmonary Fibrosis

1995 • 103 citations

Depletion of alveolar macrophages by liposome-encapsulated dichloromethylene diphosphonate

1993 • 91 citations

Pulmonary Cytokine and Chemokine mRNA Levels after Inhalation of Lipopolysaccharide in C57BL/6 Mice

1998 • 90 citations

Cytokines in human lung fibrosis

1996 • 90 citations

Long-Term Overproduction of Collagen in Radiation-Induced Fibrosis

1991 • 86 citations

Blockade of CD40–CD40 Ligand Interactions Protects against Radiation-Induced Pulmonary Inflammation and Fibrosis

1998 • 84 citations

Th2 cells as effectors in postirradiation pulmonary damage preceding fibrosis in the rat

1999 • 82 citations

Alterations in the Expression of Chemokine Mrna Levels in Fibrosis-Resistant and -Sensitive Mice After Thoracic Irradiation

1998 • 82 citations

The underlying cellular mechanism of fibrosis.

1996 • 74 citations

Increased transforming growth factor β (TGF-β) immunoreactivity is independently associated with chronic injury in both consequential and primary radiation enteropathy

1997 • 71 citations

Cell Injury and Interstitial Inflammation in Rat Lung after Inhalation of Ozone and Urban Particulates

1999 • 59 citations

Morphologic changes reflecting early and late effects of irradiation of the distal lung of the mouse: a review.

1982 • 44 citations

Endotoxin Potentiates Ozone-Induced Mucous Cell Metaplasia in Rat Nasal Epithelium

1998 • 31 citations

Biochemical and Cellular Mechanisms of Pulmonary Fibrosis*1

1991 • 28 citations

Messages and handshakes: cellular interactions in pulmonary fibrosis

1995 • 28 citations

Temporal Sequence of Early Alterations in Rat Lung Following Thoracic X-irradiation

1991 • 27 citations

Pulmonary Immunity to Listeria Is Enhanced by Elimination of Alveolar Macrophages

1999 • 26 citations

ENDOTOXIN PRIMING AFFECTS THE LUNG RESPONSE TO ULTRAFINE PARTICLES AND OZONE IN YOUNG AND OLD RATS

2000 • 26 citations

The role of leukocytes in the pathogenesis of fibrin deposition in bovine acute lung injury.

1991 • 23 citations

Endotoxin Priming Affects the Lung Response to Ultrafine Particles and Ozone in Young and Old Rats

2000 • 15 citations

Radiation-induced fibrosis: the structure/function relationship.

1994 • 15 citations

Toxicologic interactions between ozone and bacterial endotoxin

1987 • 14 citations

ENDOTOXIN POTENTIATES OZONE-INDUCED PULMONARY CHEMOKINE AND INFLAMMATORY RESPONSES

2002 • 14 citations

Radiation-induced changes in lung tissue and development of fibrosis determined by quantitative morphometric methods

1991 • 12 citations