Radiation and the lung: A reevaluation of the mechanisms mediating pulmonary injury

Clinical Radiation Pathology

1968 • 930 citations

Platelet-derived growth factor in chemotactic for fibroblasts.

1982 • 744 citations

Interstitial Lung Diseases of Unknown Cause

1984 • 696 citations

Pulmonary Effects of Radiation Therapy

1977 • 575 citations

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.

1989 • 473 citations

Interstitial Lung Diseases of Unknown Cause

1984 • 472 citations

Cytokines of the Lung

1990 • 443 citations

Exaggerated Spontaneous Release of Platelet-Derived Growth Factor by Alveolar Macrophages from Patients with Idiopathic Pulmonary Fibrosis

1987 • 420 citations

Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.

1991 • 410 citations

Radiation pneumonitis following large single dose irradiation: A re-evaluation based on absolute dose to lung

1981 • 274 citations

Alveolar macrophages release an insulin-like growth factor I-type molecule.

1988 • 255 citations

Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders.

1983 • 217 citations

Molecular biology mechanisms in the radiation induction of pulmonary injury syndromes: Interrelationship between the alveolar macrophage and the septal fibroblast

1992 • 216 citations

Applied Respiratory Physiology

1987 • 204 citations

Ionizing radiation activates transcription of the EGR1 gene via CArG elements.

1992 • 200 citations

Effects of irradiation on the release of growth factors from cultured bovine, porcine, and human endothelial cells.

1989 • 197 citations

Radiation Pneumonitis: A Possible Lymphocyte-mediated Hypersensitivity Reaction

1993 • 195 citations

Acute radiation-induced pulmonary damage: A clinical study on the response to fractionated radiation therapy

1987 • 194 citations

Lung T Cells in Hypersensitivity Pneumonitis

1984 • 192 citations

Radiation effects in the lung.

1986 • 174 citations

The sequence of histological changes in mouse lungs after single doses of X-rays

1980 • 174 citations

Growth Factors And Wound Healing: Platelet-Derived Growth Factor As A Model Cytokine

1991 • 169 citations

Biological Consequences of Gene Regulation After Ionizing Radiation Exposure

1991 • 160 citations

T-Lymphocytosis in Bronchoalveolar Lavage Fluid of Hypersensitivity Pneumonitis

1984 • 148 citations

Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes.

1991 • 148 citations

The pathogenesis of radiation-induced lung damage

1981 • 139 citations

Pathology of Irradiation

1971 • 135 citations

Bilateral radiation pneumonitis, a complication of the radiotherapy of bronchogenic carcinoma (report and analysis of seven cases with autopsy)

1969 • 132 citations

Radiopathology of Organs and Tissues

1991 • 126 citations

Methotrexate Pneumonitis: Bronchoalveolar Lavage Findings Suggest an Immunologic Disorder

1989 • 118 citations

Pathologic changes in the lung following single and multi-fraction irradiation

1977 • 116 citations

Idiopathic Pulmonary Fibrosis: Abnormalities in the Bronchoalveolar Lavage Content of Surfactant Protein A

1991 • 112 citations

Radiation-Induced Lung Injury: A Hypersensitivity Pneumonitis?

1988 • 107 citations

Pathogenesis of Pulmonary Fibrosis in Interstitial Lung Disease: Alveolar Macrophage PDGF(B) Gene Activation and Up-regulation by Interferon Gamma

1991 • 91 citations

Regulation of insulin-like growth factor I gene expression in the human macrophage-like cell line U937.

1990 • 86 citations

The early release of surfactant following lung irradiation of alveolar type II cells

1980 • 81 citations

Specific early fine structural changes in the lung following irradiation

1977 • 81 citations

The expression of early and late damage after thoracic irradiation: a comparison between CBA and C57B1 mice.

1983 • 73 citations

Interaction of Immune and Connective Tissue Cells: I. The Effect of Lymphokines and Monokines on Fibroblast Growth

1990 • 67 citations

Computer-Based Quantitative Analysis of Gallium-67 Uptake in Normal and Diseased Lungs

1983 • 61 citations

Complications of Cancer Management

1991 • 58 citations

The relationship between functional assays of radiation response in the lung and target cell depletion.

1986 • 57 citations

The Expression of Early and Late Damage after Thoracic Irradiation: A Comparison between CBA and C57Bl Mice

1983 • 56 citations

RADIATION PNEUMONITIS. CASE REPORT OF BILATERAL REACTION AFTER UNILATERNAL IRRADIATION.

1964 • 54 citations

Identification of the major fibroblast growth factors released spontaneously in inflammatory arthritis as platelet derived growth factor and tumour necrosis factor-alpha

1991 • 52 citations

Hypersensitivity pneumonitis: Correlation of cellular and immunologic changes with clinical phases of disease

1988 • 52 citations

RADIATION EFFECTS ON THE PULMONARY SYSTEM.

1971 • 48 citations

Early radiation dose-response in lung: An ultrastructural study

1977 • 47 citations

Radiopathology of Organs and Tissues

1992 • 42 citations

Complications of Cancer Management

1991 • 41 citations

Use of bronchoalveolar lavage in the evaluation of methotrexate lung disease.

1987 • 40 citations

Sequential effects of irradiation on the pulmonary surfactant system

1982 • 36 citations

Intra-alveolar Release of a Competence-type Growth Factor after Lung Injury^1–3

1986 • 33 citations

Bronchoalveolar lavage in radiation pneumonitis.

1984 • 28 citations

Hypersensitivity Pneumonitis in Athymic Nude Mice: Additional Evidence of T Cell Dependency

1992 • 27 citations

Cytokine Receptors of the Lung

1991 • 27 citations

Fibroblast growth factors in connective tissue disease associated interstitial lung disease

1992 • 21 citations

Radiation Injury of the Lung: Experimental Studies, Observations After Radiotherapy and Total Body Irradiation Prior to Bone Marrow Transplantation

1991 • 18 citations

Diffuse Gallium-67 Uptake in Radiation Pneumonitis

1990 • 17 citations

Experimental Hypersensitivity Pneumonitis in the Rat: Histopathology and T-cell Subset Compartmentalization

1991 • 15 citations

The differing patterns of interstitial lung involvement in connective tissue diseases.

1992 • 15 citations

THE ROLE OF BRONCHOALVEOLAR LAVAGE IN THE ASSESSMENT OF DIFFUSE LUNG DISEASES

1989 • 14 citations

Quantitative pulmonary gallium scanning in interstitial lung disease

1992 • 12 citations

Abnormal Bronchoalveolar Lavage in Asymptomatic Dairy Farmers

2015 • 11 citations

The identification of new early molecular mechanisms in the pathogenesis of radiation-induced pulmonary fibrosis

1991 • 10 citations

Cellular immune responses in the lung of hypersensitivity pneumonitis

1990 • 9 citations

Radiobiologic studies of growth plate chondrocytes: Mediation of radiation injury by autocrine growth factors (Supported by a 1990–1991 ASTRO Research Fellowship)

1991 • 8 citations

Mitotic Activity in the Dermis of Mice During Graft Versus Host Disease: The Role of Fibroblast Replication in Dermal Fibrosis

1992 • 6 citations

BREAST CANCER: THE ROLE OF POSTOPERATIVE RADIOTHERAPY

1989 • 5 citations