Mammary ECM composition and function are altered by reproductive state

Dissemination and growth of cancer cells in metastatic sites

2002 • 3,796 citations

The extracellular matrix as a cell survival factor.

1993 • 1,541 citations

Basement membrane complexes with biological activity

1986 • 1,489 citations

ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

1997 • 1,311 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis

1986 • 989 citations

The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini

2002 • 763 citations

Differentiation of the mammary gland and susceptibility to carcinogenesis

1982 • 629 citations

A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections.

1985 • 615 citations

A murine tumor producing a matrix of basement membrane.

1977 • 602 citations

Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo

1995 • 601 citations

Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells.

1987 • 591 citations

Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways

1996 • 538 citations

Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution.

1992 • 445 citations

The Influence of Extracellular Matrix on Gene Expression: Is Structure The Message?

1987 • 437 citations

The influence of the microenvironment on the malignant phenotype

2000 • 398 citations

Mesenchyme-Dependent Morphogenesis and Epithelium-Specific Cytodifferentiation in Mouse Mammary Gland

1976 • 348 citations

Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle.

1996 • 333 citations

Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium

1996 • 292 citations

Active cell death in hormone-dependent tissues

1992 • 264 citations

Apoptosis in the terminal endbud of the murine mammary gland: a mechanism of ductal morphogenesis

1996 • 256 citations

Tenascin in normal, reactive, hyperplastic, and neoplastic tissues: Biologic and pathologic implications

1991 • 225 citations

REGULATION OF MILK PROTEIN GENE EXPRESSION

1999 • 217 citations

Distribution of myoepithelial cells and basement membrane proteins in the resting, pregnant, lactating, and involuting rat mammary gland.

1982 • 213 citations

Nurses' Health Study: Log-Incidence Mathematical Model of Breast Cancer Incidence

1996 • 213 citations

The fibronectin gene as a model for splicing and transcription studies

1996 • 198 citations

Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death.

1994 • 170 citations

Postnatal mammary gland morphogenesis

2001 • 165 citations

Evidence that tenascin and thrombospondin-1 modulate sprouting of endothelial cells

1995 • 132 citations

Roles of the matrix metalloproteinases in mammary gland development and cancer

1998 • 132 citations

A developmental atlas of rat mammary gland histology.

2000 • 131 citations

Estrous cycle regulation of mammary epithelial cell proliferation, differentiation, and death in the Sprague-Dawley rat: a model for investigating the role of estrous cycling in mammary carcinogenesis.

2000 • 128 citations

Refractoriness to mammary tumorigenesis in parous rats: is it caused by persistent changes in the hormonal environment or permanent biochemical alterations in the mammary epithelia?

1995 • 119 citations

Reproductive state of rat mammary gland stroma modulates human breast cancer cell migration and invasion.

2000 • 118 citations

Development of mammary preneoplasias in vivo from mouse mammary epithelial cell lines in vitro.

1992 • 111 citations

Multistep tumorigenesis and the microenvironment

2004 • 102 citations

Adhesion-mediated signaling in the regulation of mammary epithelial cell survival.

1999 • 100 citations

Transforming Growth Factor-β Initiates Wound Repair in Rat Liver through Induction of the EIIIA-Fibronectin Splice Isoform

2000 • 89 citations

Fibronectin fragments induce MMP activity in mouse mammary epithelial cells: evidence for a role in mammary tissue remodeling

2000 • 87 citations

Tumour-stromal interactions. Role of the stroma in mammary development.

2001 • 77 citations

Expression of Matrix Metalloprotease-2-Cleaved Laminin-5 in Breast Remodeling Stimulated by Sex Steroids

1999 • 77 citations

Enhanced synthesis of gelatinase and stromelysin by myoepithelial cells during involution of the rat mammary gland.

1992 • 77 citations

Topographical arrangement of basement membrane proteins in lactating rat mammary gland: comparison of the distribution of type IV collagen, laminin, fibronectin, and Thy-1 at the ultrastructural level.

1983 • 75 citations

Laminin and tenascin assembly and expression regulate HC11 mouse mammary cell differentiation

1994 • 74 citations

Tenascin-c inhibits extracellular matrix-dependent gene expression in mammary epithelial cells: localization of active regions using recombinant tenascin fragments

1995 • 73 citations

Tumour-stromal interactions. Transforming growth factor-beta isoforms and hepatocyte growth factor/scatter factor in mammary gland ductal morphogenesis.

2001 • 67 citations

Regulation of VEGF and VEGF receptor expression in the rodent mammary gland during pregnancy, lactation, and involution

2000 • 65 citations

Tenascin distribution in the normal human breast is altered during the menstrual cycle and in carcinoma

1990 • 63 citations

The Fibrinogen Globe of Tenascin-C Promotes Basic Fibroblast Growth Factor-induced Endothelial Cell Elongation

1999 • 61 citations

Tumour-stromal interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation.

2001 • 57 citations

Tumour-stromal interactions Reciprocal regulation of extracellular matrix proteins and ovarian steroid activity in the mammary gland

2001 • 50 citations

Primary culture of normal rat mammary epithelial cells within a basement membrane matrix. II. Functional differentiation under serum-free conditions

1990 • 48 citations

The development of the terminal end bud in the prepubertal-pubertal mouse mammary gland

1998 • 44 citations

Developmental response of adult mammary epithelial cells to various fetal and neonatal mesenchymes.

1992 • 42 citations

Prolactin and epidermal growth factor regulation of the proliferation, morphogenesis, and functional differentiation of normal rat mammary epithelial cells in three dimensional primary culture

1995 • 41 citations

Analysis of tenascin mRNA expression in the murine mammary gland from embryogenesis to carcinogenesis: an in situ hybridization study.

1997 • 39 citations

Regulation of mammary differentiation by the extracellular matrix.

1989 • 37 citations

Mammary epithelial cell differentiation in vitro is regulated by an interplay of egf action and tenascin-c downregulation

1995 • 34 citations

Tenascin in mammary gland development: From embryogenesis to carcinogenesis

1991 • 31 citations

Intralobular stromal fibroblasts in the resting human mammary gland: ultrastructural properties and intercellular relationships.

1986 • 29 citations

Programmed cell death and mammary neoplasia

1996 • 28 citations

Modulation of Clusterin Gene Expression in the Rat Mammary Gland during Pregnancy, Lactation, and Involution1

1996 • 25 citations

Tenascin Expression and Angiogenesis in Breast Cancers

1999 • 25 citations

Signal transduction via the fibronectin receptor: do integrins regulate matrix remodeling?

1992 • 22 citations

Treatment with chemopreventive agents, difluoromethylornithine and retinyl acetate, results in altered mammary extracellular matrix

1995 • 20 citations

Ultrastructural observations on the basal lamina in the normal human breast.

1988 • 18 citations

Regulation of Mammary Differentiation by the Extracellular Matrix

1989 • 9 citations