Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo

Establishment in culture of pluripotential cells from mouse embryos

1981 • 8,424 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.

1981 • 5,629 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1994 • 2,293 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

The extracellular matrix as a cell survival factor.

1993 • 1,541 citations

Programmed Cell Death and the Control of Cell Survival: Lessons from the Nervous System

1993 • 1,470 citations

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1993 • 1,387 citations

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.

1991 • 1,358 citations

Cell death and control of cell survival in the oligodendrocyte lineage

1992 • 1,331 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

CELL DEATHS IN NORMAL VERTEBRATE ONTOGENY

1951 • 1,194 citations

Suppression of ICE and Apoptosis in Mammary Epithelial Cells by Extracellular Matrix

1995 • 1,184 citations

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

1986 • 1,118 citations

Apoptosis and Programmed Cell Death in Immunity

1992 • 1,105 citations

Proliferation, differentiation and degeneration in the spinal ganglia of the chick embryo under normal and experimental conditions

1949 • 974 citations

Death in Embryonic Systems

1966 • 943 citations

Teratocarcinomas and Mammalian Embryogenesis

1980 • 767 citations

Chemotropic guidance of developing axons in the mammalian central nervous system

1988 • 681 citations

Immunosurgery of mouse blastocyst.

1975 • 669 citations

Gene Targeting: A Practical Approach

1994 • 592 citations

Gene targeting: a practical approach.

1993 • 585 citations

FGF5 as a regulator of the hair growth cycle: Evidence from targeted and spontaneous mutations

1994 • 575 citations

Induction of a Common Pathway of Apoptosis by Staurosporine

1994 • 491 citations

Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen.

1994 • 447 citations

Palate development

1988 • 440 citations

Neoplastic differentiation: Characteristics of cell lines derived from a murine teratocarcinoma

1974 • 359 citations

Macrophages are required for cell death and tissue remodeling in the developing mouse eye

1993 • 355 citations

Gastrulation in the mouse : Growth and regionalization of the epiblast

1977 • 340 citations

Perspectives on mammalian cell death

1988 • 334 citations

Cell death in biology and pathology

1981 • 290 citations

The development of cystic embryoid bodies in vitro from clonal teratocarcinoma stem cells

1977 • 223 citations

Identification and characterization of cell-substratum adhesion receptors on cultured human endothelial cells.

1989 • 186 citations

Perspectives on mammalian cell death.

1987 • 183 citations

Development of the vagina in the human fetus.

1933 • 144 citations

Cell death in embryogenesis

1981 • 138 citations

The development in vitro of the submandibular and sublingual glands of Mus musculus.

1950 • 114 citations

Internucleosomal dna fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg bud

1993 • 113 citations

Cell interactions and endoderm differentiation in cultured mouse embryos

1981 • 110 citations

Visceral-endoderm-like cell lines induce differentiation of murine P19 embryonal carcinoma cells

1991 • 107 citations

Clonal variants of differentiated P19 embryonal carcinoma cells exhibit epidermal growth factor receptor kinase activity

1985 • 107 citations

Cell redundancy in the zona-intact preimplantation mouse blastocyst: a light and electron microscope study of dead cells and their fate.

1974 • 102 citations

Inhibition of palatal epithelial cell death by altered protein synthesis

1976 • 100 citations

Embryology of the Mullerian duct syytem. Review of present-day theory.

1962 • 85 citations

Induction of Apoptosis by the Anti-Tubulin Drug Colcemid: Relationship of Mitotic Checkpoint Control to the Induction of Apoptosis in HeLa S3 Cells

1994 • 63 citations

Cell death in biology and pathology

1982 • 38 citations

Cell redundancy in the zona-intact preimplantation mouse blastocyst: a light and electron microscope study of dead cells and their fate

1974 • 34 citations

Modulation of growth factor responsiveness of murine mammary carcinoma cells by cell matrix interactions: Correlation of cell proliferation and spreading

1992 • 33 citations