Tumour-stromal interactions Reciprocal regulation of extracellular matrix proteins and ovarian steroid activity in the mammary gland

Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction

1996 • 772 citations

Mammary gland development and tumorigenesis in estrogen receptor knockout mice.

1997 • 354 citations

Elucidation of a role for stromal steroid hormone receptors in mammary gland growth and development using tissue recombinants.

1997 • 216 citations

Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells.

1992 • 176 citations

Mammary gland growth and development from the postnatal period to postmenopause: ovarian steroid receptor ontogeny and regulation in the mouse.

1998 • 144 citations

New Aspects of Stroma-Parenchyma Relations in Mammary Gland Differentiation

1991 • 140 citations

Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones.

2000 • 133 citations

The integrin α6β4 and the biology of carcinoma

1996 • 123 citations

Mammary fibroblast influence on normal mouse mammary epithelial cell responses to estrogen in vitro.

1986 • 117 citations

The spatial and temporal expression of the α2β1 integrin and its ligands, collagen I, collagen IV, and laminin, suggest important roles in mouse mammary morphogenesis

1995 • 111 citations

Progesterone Effects on Deoxyribonucleic Acid Synthesis in Normal Mouse Mammary Glands*

1988 • 110 citations

The Insulin-Like Growth Factors (IGF) and IGF Type I Receptor during Postnatal Growth of the Murine Mammary Gland: Sites of Messenger Ribonucleic Acid Expression and Potential Functions**This work was supported, in part, by NIH Grant DK-48103 (to T.L.W.)

1999 • 86 citations

The role of mammary stroma in modulating the proliferative response to ovarian hormones in the normal mammary gland.

1998 • 83 citations

Fibronectin and the α5β1 Integrin Are Under Developmental and Ovarian Steroid Regulation in the Normal Mouse Mammary Gland

2001 • 82 citations

Developmental Expression and Cellular Origin of the Laminin α2, α4, and α5 Chains in the Intestine

1999 • 80 citations

Laminin-binding integrins in tumor progression and metastasis

1996 • 65 citations

Extracellular Matrix Regulates Ovarian Hormone-Dependent Proliferation of Mouse Mammary Epithelial Cells¹

1997 • 57 citations

Local Versus Systemically Mediated Effects of Estrogen on Normal Mammary Epithelial Cell Deoxyribonucleic Acid Synthesis*

1988 • 51 citations

Proliferation of Mouse Mammary Epithelial Cells in Vitro: Interactions among Epidermal Growth Factor, Insulin-Like Growth Factor I, Ovarian Hormones, and Extracellular Matrix Proteins*

2000 • 41 citations

Synthesis of Basement Membrane Proteins in the Small Intestine

1990 • 41 citations

Laminin Inhibits Estrogen Action in Human Breast Cancer Cells1

2000 • 31 citations

Estrogen treatment in vivo increases keratinocyte growth factor expression in the mammary gland

2000 • 27 citations

Growth factor and sex steroid interactions in breast cancer

1996 • 27 citations

Gene diagnostics provide new insights into breast cancer prognosis and therapy

1995 • 26 citations

Antiestrogen resistance in ER positive breast cancer cells

1994 • 26 citations

Regulation of estrogen receptor expression

1994 • 21 citations