Opposite Regulation of Transepithelial Electrical Resistance and Paracellular Permeability by Rho in Madin-Darby Canine Kidney Cells

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

Occludin: a novel integral membrane protein localizing at tight junctions.

1993 • 2,466 citations

Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

1998 • 2,005 citations

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

1986 • 1,588 citations

The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

1995 • 1,280 citations

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.

1994 • 949 citations

A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts

1998 • 923 citations

Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein.

1996 • 849 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

MOLECULAR ARCHITECTURE OF TIGHT JUNCTIONS

1998 • 718 citations

Occludin is a functional component of the tight junction

1996 • 632 citations

Occludin as a possible determinant of tight junction permeability in endothelial cells

1997 • 626 citations

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

1994 • 617 citations

Rho Family GTPases and Neuronal Growth Cone Remodelling: Relationship between Increased Complexity Induced by Cdc42Hs, Rac1, and Acetylcholine and Collapse Induced by RhoA and Lysophosphatidic Acid

1997 • 601 citations

ZO-3, a Novel Member of the MAGUK Protein Family Found at the Tight Junction, Interacts with ZO-1 and Occludin

1998 • 592 citations

Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes.

1996 • 560 citations

Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells

1997 • 555 citations

Asparagine residue in the rho Gene Product Is the Modification Site for Botulinum ADP-ribosyltransferase

1989 • 550 citations

Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

1993 • 546 citations

Structure, biochemistry, and assembly of epithelial tight junctions

1987 • 532 citations

A Synthetic Peptide Corresponding to the Extracellular Domain of Occludin Perturbs the Tight Junction Permeability Barrier

1997 • 527 citations

Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.

1991 • 520 citations

Cingulin, a new peripheral component of tight junctions

1988 • 505 citations

Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.

1994 • 469 citations

Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein

1994 • 452 citations

Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia.

1995 • 418 citations

The Small GTPase Rho: Cellular Functions and Signal Transduction

1996 • 404 citations

Molecular mechanisms of diverse actions of prostanoid receptors

1995 • 390 citations

Breaking through the tight junction barrier.

1993 • 379 citations

Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype.

1992 • 353 citations

Structural and Functional Regulation of Tight Junctions by RhoA and Rac1 Small GTPases

1998 • 349 citations

Symplekin, a novel type of tight junction plaque protein.

1996 • 286 citations

Assembly and sealing of tight junctions: Possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin

1991 • 280 citations

A novel inhibitory prostanoid receptor in piglet saphenous vein

1994 • 273 citations

Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2.

1993 • 266 citations

A general method for introducing a series of mutations into cloned DNA using the polymerase chain reaction

1991 • 253 citations

Clostridium botulinum type C produces a novel ADP‐ribosyltransferase distinct from botulinum C2 toxin

1987 • 238 citations

Tight junctions

1998 • 197 citations

Lysophosphatidic Acid Increases Tight Junction Permeability in Cultured Brain Endothelial Cells

1997 • 172 citations

p160 RhoA-binding Kinase ROKα Induces Neurite Retraction

1998 • 166 citations

Involvement of a Heterotrimeric G Protein α Subunit in Tight Junction Biogenesis

1996 • 136 citations

Identification of Isoforms of G Proteins and PKC that Colocalize with Tight Junctions

1996 • 127 citations

Prostanoid inhibition of canine parietal cells: Mediation by the inhibitory guanosine triphosphate-binding protein of adenylate cyclase

1988 • 123 citations

Two Isoforms of the Prostaglandin E Receptor EP3 Subtype Different in Agonist-independent Constitutive Activity

1996 • 106 citations

Prostaglandin E receptors in bovine adrenal medulla are coupled to adenylate cyclase via Gi and to phosphoinositide metabolism in a pertussis toxin-insensitive manner

1989 • 97 citations

Histamine reduces ZO-1 tight-junction protein expression in cultured retinal microvascular endothelial cells

1996 • 95 citations

Involvement of Gαi2 in the Maintenance and Biogenesis of Epithelial Cell Tight Junctions

1998 • 85 citations

Prostaglandin E Receptor EP3 Subtype Induces Neurite Retraction via Small GTPase Rho

1996 • 71 citations

Establishment of tight junctions between cells from different animal species and different sealing capacities

1989 • 68 citations

Glucocorticoid-induced Functional Polarity of Growth Factor Responsiveness Regulates Tight Junction Dynamics in Transformed Mammary Epithelial Tumor Cells

1995 • 55 citations

Prejunctional inhibitory effects of prostanoids on sympathetic neurotransmission in the rabbit iris-ciliary body.

1990 • 49 citations

Interaction of prostaglandin E2 and β-adrenergic catecholamines in the regulation of uterine smooth muscle motility and adenylate cyclase in the rat

1984 • 45 citations

Serum Opens Tight Junctions and Reduces ZO‐1 Protein in Retinal Epithelial Cells

1997 • 44 citations

Targeting of chimeric Gαi proteins to specific membrane domains

1994 • 38 citations

Two Isoforms of Prostaglandin EP3 Receptor Exhibiting Constitutive Activity and Agonist-Dependent Activity in Rho-Mediated Stress Fiber Formation

1997 • 34 citations

Differential Localization of G-proteins, Gαo and Gαi-1, -2, and -3, in Polarized Epithelial MDCK Cells

1997 • 17 citations