Prostaglandin E Receptor EP3 Subtype Induces Neurite Retraction via Small GTPase Rho

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Developmental mechanisms that generate precise patterns of neuronal connectivity

1993 • 1,435 citations

Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids

1993 • 1,222 citations

Prostaglandins, Aspirin-like Drugs and Analgesia

1972 • 871 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

1994 • 617 citations

Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, and Other Derivatives of Carbon‐20 Unsaturated Fatty Acids

1982 • 580 citations

Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes.

1996 • 560 citations

Asparagine residue in the rho Gene Product Is the Modification Site for Botulinum ADP-ribosyltransferase

1989 • 550 citations

Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

1993 • 546 citations

Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype.

1993 • 475 citations

Gα12 and Gα13 Stimulate Rho-dependent Stress Fiber Formation and Focal Adhesion Assembly

1995 • 443 citations

Molecular mechanisms of diverse actions of prostanoid receptors

1995 • 390 citations

Rho as a regulator of the cytoskeleton

1995 • 386 citations

Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor.

1993 • 381 citations

Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype.

1992 • 353 citations

A novel inhibitory prostanoid receptor in piglet saphenous vein

1994 • 273 citations

Clostridium botulinum type C produces a novel ADP‐ribosyltransferase distinct from botulinum C2 toxin

1987 • 238 citations

In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs

1995 • 234 citations

Down regulation of protein kinase C in neuronal cells: effects on neurotransmitter release

1987 • 204 citations

Lysophosphatidic Acid‐Induced Neurite Retraction in PC12 Cells: Control by Phosphoinositide‐Ca²⁺ Signaling and Rho

1996 • 198 citations

Prostaglandin E as the neural mediator of the febrile response.

1986 • 197 citations

Axon guidance molecules

1995 • 193 citations

Translocation of activated Rho from the cytoplasm to membrane ruffling area, cell-cell adhesion sites and cleavage furrows.

1995 • 192 citations

Distribution of the messenger rna for the prostaglandin e receptor subtype ep3 in the mouse nervous system

1994 • 182 citations

rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells.

1994 • 171 citations

The mouse prostaglandin E receptor EP₂ subtype: cloning, expression, and Northern blot analysis

1995 • 155 citations

Lysophosphatidic Acid‐Induced Neurite Retraction in PC12 Cells: Neurite‐Protective Effects of Cyclic AMP Signaling

1996 • 137 citations

Head Injury Induces Increased Prostaglandin Synthesis in Rat Brain

1987 • 125 citations

Experimental Traumatic Brain Injury Elevates Brain Prostaglandin E₂and Thromboxane B₂Levels in Rats

1988 • 104 citations

Formation and Function of Eicosanoids in the Central Nervous System

1989 • 84 citations

Effect of prostaglandins D2, E2 and F2α on catecholamine release from slices of rat and rabbit brain

1981 • 59 citations

Involvement of EP3 subtype of prostaglandin E receptors in PGE2-induced enhancement of the bradykinin response of nociceptors

1993 • 55 citations

An Increase in Hypothalamic Capacity to Synthesize Prostaglandin E₂Precedes the First Preovulatory Surge of Gonadotropins*

1982 • 52 citations

Prostanoid receptors of the EP3 subtype mediate the inhibitory effect of prostaglandin E2 on noradrenaline release in the mouse brain cortex

1995 • 35 citations

Increased Plasma PGE₂, 6-Keto-PGF_1α, and 12-HETE Levels Following Experimental Concussive Brain Injury

1989 • 34 citations

The effect of active serum albumin on PC12 cells: I. Neurite retraction and activation of the phosphoinositide second messenger system

1992 • 34 citations

Facilitation of noradrenaline release from rat brain synaptosomes by prostaglandin E2

1976 • 31 citations

Prostaglandins play a role in memory consolidation in the chick

1995 • 21 citations

Beagle pup model of brain injury: regional cerebral blood flow and cerebral prostaglandins

1987 • 16 citations