NOX2 and NOX4 Mediate Proliferative Response in Endothelial Cells

Free Radicals in the Physiological Control of Cell Function

2002 • 9,561 citations

NOX enzymes and the biology of reactive oxygen

2004 • 2,940 citations

HOW NEUTROPHILS KILL MICROBES

2005 • 1,707 citations

Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation

2002 • 1,516 citations

Permanent cell line expressing human factor VIII-related antigen established by hybridization.

1983 • 1,458 citations

Reactive Oxygen Species in the Vasculature

2003 • 1,052 citations

Vascular NAD(P)H oxidases: specific features, expression, and regulation

2003 • 1,029 citations

The Neutrophil NADPH Oxidase

2002 • 904 citations

Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis

2003 • 767 citations

Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology

2004 • 763 citations

Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

2005 • 752 citations

The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases

2003 • 691 citations

A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial Wall

2000 • 596 citations

The Endoplasmic Reticulum: Folding, Calcium Homeostasis, Signaling, and Redox Control

2006 • 590 citations

Distinct Subcellular Localizations of Nox1 and Nox4 in Vascular Smooth Muscle Cells

2003 • 578 citations

Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences

2005 • 560 citations

Direct Interaction of the Novel Nox Proteins with p22phox Is Required for the Formation of a Functionally Active NADPH Oxidase

2004 • 526 citations

A Novel Superoxide-producing NAD(P)H Oxidase in Kidney

2001 • 508 citations

Nox4 as the Major Catalytic Component of an Endothelial NAD(P)H Oxidase

2004 • 495 citations

Novel Role of gp91 ^phox -Containing NAD(P)H Oxidase in Vascular Endothelial Growth Factor–Induced Signaling and Angiogenesis

2002 • 464 citations

Reactive oxygen species as mediators of angiogenesis signaling. Role of NAD(P)H oxidase

2004 • 463 citations

The Nox Family of NAD(P)H Oxidases: Host Defense and Beyond

2004 • 437 citations

NAD(P)H Oxidase Nox-4 Mediates 7-Ketocholesterol-Induced Endoplasmic Reticulum Stress and Apoptosis in Human Aortic Smooth Muscle Cells

2004 • 423 citations

Assembly of the phagocyte NADPH oxidase

2004 • 415 citations

Thrombin Activates the Hypoxia-Inducible Factor-1 Signaling Pathway in Vascular Smooth Muscle Cells

2001 • 415 citations

Intracellular Localization and Preassembly of the NADPH Oxidase Complex in Cultured Endothelial Cells

2002 • 393 citations

Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Induces Monocyte Adhesion by Stimulating Reactive Oxygen Species Production From a Nox1-Based NADPH Oxidase

2004 • 369 citations

Reactive Oxygen Species Produced by NAD(P)H Oxidase Inhibit Apoptosis in Pancreatic Cancer Cells

2004 • 355 citations

Expression and Localization of NOX2 and NOX4 in Primary Human Endothelial Cells

2005 • 314 citations

Differential Expression of Voltage-Gated K ⁺ Channel Subunits in Adult Rat Heart

1995 • 253 citations

VEGF Signaling Through NADPH Oxidase-Derived ROS

2007 • 238 citations

Regulation of NAD(P)H Oxidase by Associated Protein Disulfide Isomerase in Vascular Smooth Muscle Cells

2005 • 234 citations

Point Mutations in the Proline-rich Region of p22 Are Dominant Inhibitors of Nox1- and Nox2-dependent Reactive Oxygen Generation

2005 • 224 citations

Novel NAD(P)H oxidases in the cardiovascular system

2004 • 216 citations

An NAD(P)H oxidase regulates growth and transcription in melanoma cells

2002 • 171 citations

Human Urotensin II Is a Novel Activator of NADPH Oxidase in Human Pulmonary Artery Smooth Muscle Cells

2004 • 164 citations

NAD(P)H oxidase plays a crucial role in PDGF-induced proliferation of hepatic stellate cells

2005 • 161 citations

Evidence for small intracellular vesicles in human blood phagocytes containing cytochrome b558 and the adhesion molecule CD11b/CD18

1993 • 143 citations

NAD(P)H Oxidases in Rat Basilar Arterial Endothelial Cells

2005 • 136 citations

The expression of the NADPH oxidase subunit p22phox is regulated by a redox-sensitive pathway in endothelial cells

2004 • 133 citations

Pivotal Role of gp91 ^phox -Containing NADH Oxidase in Lipopolysaccharide-Induced Tumor Necrosis Factor-α Expression and Myocardial Depression

2005 • 124 citations

IQGAP1 Regulates Reactive Oxygen Species–Dependent Endothelial Cell Migration Through Interacting With Nox2

2005 • 122 citations

Systemic Regulation of Vascular NAD(P)H Oxidase Activity and Nox Isoform Expression in Human Arteries and Veins

2004 • 120 citations

NADPH Oxidase Mediates Tissue Factor–Dependent Surface Procoagulant Activity by Thrombin in Human Vascular Smooth Muscle Cells

2002 • 115 citations

Regulation of NADPH oxidase subunit p22^phoxby NF-kB in human aortic smooth muscle cells

2007 • 109 citations

Atrial Natriuretic Peptide Induces Mitogen-Activated Protein Kinase Phosphatase-1 in Human Endothelial Cells via Rac1 and NAD(P)H Oxidase/Nox2-Activation

2004 • 108 citations

Pigment epithelium-derived factor (PEDF) blocks angiotensin II signaling in endothelial cells via suppression of NADPH oxidase: a novel anti-oxidative mechanism of PEDF

2005 • 108 citations

NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation

2005 • 90 citations

Insights into the Redox Control of Blood Coagulation: Role of Vascular NADPH Oxidase-Derived Reactive Oxygen Species in the Thrombogenic Cycle

2004 • 71 citations

Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1

2003 • 65 citations

Nox1 regulates apoptosis and potentially stimulates branching morphogenesis in sinusoidal endothelial cells

2004 • 65 citations

Nox2 regulates endothelial cell cycle arrest and apoptosis via p21cip1 and p53

2007 • 62 citations

Redox Signaling through NADPH Oxidases: Involvement in Vascular Proliferation and Coagulation

2002 • 53 citations

Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1.

2003 • 48 citations

Experimental Strategies in Efficient Transfection of Mammalian Cells: Calcium Phosphate and DEA E- Dextran

2003 • 14 citations