Pivotal Role of gp91 ^phox -Containing NADH Oxidase in Lipopolysaccharide-Induced Tumor Necrosis Factor-α Expression and Myocardial Depression

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

1996 • 2,456 citations

The Neutrophil NADPH Oxidase

2002 • 904 citations

Increased NADH-Oxidase–Mediated Superoxide Production in the Early Stages of Atherosclerosis

1999 • 689 citations

Increased myocardial NADPH oxidase activity in human heart failure

2003 • 570 citations

NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia

2004 • 562 citations

Pivotal Role of a gp91 ^phox -Containing NADPH Oxidase in Angiotensin II-Induced Cardiac Hypertrophy in Mice

2002 • 524 citations

Activation of NADPH Oxidase During Progression of Cardiac Hypertrophy to Failure

2002 • 507 citations

The Haber-Weiss cycle – 70 years later

2001 • 448 citations

Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration.

1995 • 436 citations

Redox regulation of glial inflammatory response to lipopolysaccharide and interferonγ

2004 • 410 citations

Contrasting Roles of NADPH Oxidase Isoforms in Pressure-Overload Versus Angiotensin II–Induced Cardiac Hypertrophy

2003 • 407 citations

Novel homologs of gp91phox

2000 • 356 citations

Role of reactive oxygen species and NAD(P)H oxidase in α₁-adrenoceptor signaling in adult rat cardiac myocytes

2002 • 297 citations

Uptake and transport of high‐density lipoprotein (HDL) and HDL‐associated α‐tocopherol by an in vitro blood–brain barrier model

2004 • 220 citations

Role of reactive oxygen species in LPS‐induced production of prostaglandin E₂ in microglia

2004 • 216 citations

Role of NADPH Oxidase in the Mechanism of Lung Neutrophil Sequestration and Microvessel Injury Induced by Gram-Negative Sepsis: Studies in p47phox−/− and gp91phox−/− Mice

2002 • 178 citations

Tumor necrosis factor-α induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes

2000 • 171 citations

Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats

2002 • 149 citations

A central role for the endothelial NADPH oxidase in atherosclerosis

2000 • 147 citations

Lactate and P <scp>o</scp> ₂ Modulate Superoxide Anion Production in Bovine Cardiac Myocytes

1997 • 146 citations

Role of Increased Production of Superoxide Anions by NAD(P)H Oxidase and Xanthine Oxidase in Prolonged Endotoxemia

1999 • 125 citations

Endotoxin-Induced Myocardial Tumor Necrosis Factor-α Synthesis Depresses Contractility of Isolated Rat Hearts

2000 • 123 citations

Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production

2001 • 119 citations

Infarct Size and Nitric Oxide Synthase in Murine Myocardium

2000 • 113 citations

Myocardial dysfunction in septic shock: Part II. Role of cytokines and nitric oxide

2001 • 109 citations

The effect of natural antioxidants, NAO and apocynin, on oxidative stress in the rat heart following LPS challenge

2001 • 106 citations

Inhibition of p38 MAPK decreases myocardial TNF-alpha expression and improves myocardial function and survival in endotoxemia

2003 • 97 citations

Effect of the NADPH oxidase inhibitor apocynin on septic lung injury in guinea pigs.

1994 • 86 citations

Myocardial Glucose Uptake Is Regulated by Nitric Oxide via Endothelial Nitric Oxide Synthase in Langendorff Mouse Heart

2000 • 84 citations

Superoxide mediates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules

2003 • 80 citations

Cardiac Inflammation and Innate Immunity in Septic Shock

2002 • 76 citations

Endothelial Nitric-oxide Synthase Enhances Lipopolysaccharide-stimulated Tumor Necrosis Factor-α Expression via cAMP-mediated p38 MAPK Pathway in Cardiomyocytes

2003 • 73 citations