Interactions of Nucleotide Release Factor Dss4p with Sec4p in the Post-Golgi Secretory Pathway of Yeast

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

[1] Getting started with yeast

1991 • 2,456 citations

Proteins regulating Ras and its relatives

1993 • 1,930 citations

COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum

1994 • 1,294 citations

Cold Spring Harbor Laboratory

1995 • 1,077 citations

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

1994 • 948 citations

A ras-like protein is required for a post-Golgi event in yeast secretion

1987 • 894 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

The two-hybrid system: an assay for protein-protein interactions

1994 • 649 citations

Vesicle fusion from yeast to man

1994 • 635 citations

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

1988 • 592 citations

Protein motifs 5. Zinc fingers.

1995 • 544 citations

Zinc fingers

1995 • 501 citations

Applications of high efficiency lithium acetate transformation of intact yeast cells using single‐stranded nucleic acids as carrier

1991 • 433 citations

Interaction of the Nuclear GTP-Binding Protein Ran with Its Regulatory Proteins RCC1 and RanGAP1

1995 • 334 citations

The role of Myo2, a yeast class V myosin, in vesicular transport.

1995 • 324 citations

GTPase activity of Rab5 acts as a timer for endocytic membrane fusion

1996 • 322 citations

Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange

1994 • 313 citations

Regulation of reversible binding of smg p25A, a ras p21-like GTP-binding protein, to synaptic plasma membranes and vesicles by its specific regulatory protein, GDP dissociation inhibitor.

1990 • 268 citations

Kinetic and structural analysis of the Mg(2+)-binding site of the guanine nucleotide-binding protein p21H-ras.

1993 • 260 citations

Rab GDP Dissociation Inhibitor: Putting Rab GTPases in the Right Place

1995 • 240 citations

Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange

1994 • 230 citations

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP.

1991 • 211 citations

Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast.

1994 • 211 citations

GDI1 encodes a GDP dissociation inhibitor that plays an essential role in the yeast secretory pathway.

1994 • 200 citations

Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4

1993 • 190 citations

Purification and characterization of constitutive secretory vesicles from yeast.

1987 • 179 citations

Structure and mutational analysis of Rab GDP-dissociation inhibitor

1996 • 173 citations

Two GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeast.

1996 • 172 citations

Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae.

1989 • 162 citations

Bos1p, an integral membrane protein of the endoplasmic reticulum to Golgi transport vesicles, is required for their fusion competence

1993 • 137 citations

Hydrolysis of GTP by Sec4 protein plays an important role in vesicular transport and is stimulated by a GTPase-activating protein in Saccharomyces cerevisiae.

1992 • 132 citations

Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity.

1994 • 119 citations

A mammalian guanine-nucleotide-releasing protein enhances function of yeast secretory protein Sec4

1993 • 117 citations

Specific interactions of Mss4 with members of the Rab GTPase subfamily.

1994 • 117 citations

DSS4-1 is a dominant suppressor of sec4-8 that encodes a nucleotide exchange protein that aids Sec4p function

1993 • 112 citations

Structural insights into the function of the Rab GDI superfamily

1996 • 111 citations

Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4

1993 • 105 citations

Characterization of a zinc blotting technique: evidence that a retroviral gag protein binds zinc.

1988 • 96 citations

Mutants of Rab3A analogous to oncogenic Ras mutants. Sensitivity to Rab3A-GTPase activating protein and Rab3A-guanine nucleotide releasing factor

1993 • 92 citations

Requirement of nucleotide exchange factor for Ypt1 GTPase mediated protein transport.

1995 • 74 citations

Mutation spectrum in the CHM gene of Danish and Swedish choroideremia patients

1994 • 72 citations

Cdc25p, the guanine nucleotide exchange factor for the Ras proteins of Saccharomyces cerevisiae, promotes exchange by stabilizing Ras in a nucleotide-free state

1994 • 65 citations

A GDP/GTP Exchange-stimulatory Activity for the Rab5-RabGDI Complex on Clathrin-coated Vesicles from Bovine Brain

1995 • 57 citations

Structure of guanine-nucleotide-exchange factor human Mss4 and identification of its Rab-interacting surface

1995 • 56 citations

SDC25, a dispensable Ras guanine nucleotide exchange factor of Saccharomyces cerevisiae differs from CDC25 by its regulation.

1996 • 52 citations

Inhibition of SDC25 C-domain-induced guanine-nucleotide exchange by guanine ring binding domain mutants of v-H-ras.

1993 • 40 citations

Comparison of kinetic properties between MSS4 and Rab3A GRF GDP/GTP exchange proteins

1994 • 19 citations

Site-directed mutagenesis of the GDP binding domain of bacterial elongation factor Tu

1989 • 15 citations

[26] Expression, purification, and assays of Gdilp from recombinant Escherichia coli

1995 • 10 citations

[33] Purification of Sec4 Protein from Saccharomyces Cerevisiae and Escherichia coli

1992 • 6 citations

[11] Purification of GDP dissociation stimulator Dss4 from recombinant bacteria

1995 • 2 citations