Ulp1-SUMO Crystal Structure and Genetic Analysis Reveal Conserved Interactions and a Regulatory Element Essential for Cell Growth in Yeast

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Refinement of Macromolecular Structures by the Maximum-Likelihood Method

1997 • 14,729 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

Automated MAD and MIR structure solution

1999 • 3,079 citations

Guide to Yeast Genetics and Molecular Biology

1993 • 2,377 citations

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods

1997 • 1,905 citations

UBIQUITIN-DEPENDENT PROTEIN DEGRADATION

1996 • 1,680 citations

[10] 5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1987 • 1,375 citations

[19] Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast

1991 • 1,369 citations

SETOR: Hardware-lighted three-dimensional solid model representations of macromolecules

1993 • 1,295 citations

A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

1997 • 1,221 citations

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex.

1996 • 1,161 citations

Determination of Macromolecular Structures from Anomalous Diffraction of Synchrotron Radiation

1991 • 1,123 citations

Guide to yeast genetics and molecular biology

1992 • 1,032 citations

Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure.

1990 • 1,013 citations

SUMO-1 Modification of IκBα Inhibits NF-κB Activation

1998 • 1,002 citations

Automated refinement of protein models

1993 • 893 citations

A new protease required for cell-cycle progression in yeast

1999 • 718 citations

SUMO-1 modification activates the transcriptional response of p53

1999 • 627 citations

Regulation of ubiquitin‐dependent processes by deubiquitinating enzymes

1997 • 576 citations

The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer

1997 • 543 citations

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1

1999 • 507 citations

Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins

1995 • 492 citations

Ubc9p Is the Conjugating Enzyme for the Ubiquitin-like Protein Smt3p

1997 • 488 citations

Substrate Targeting in the Ubiquitin System

1999 • 447 citations

Structure determination of the small ubiquitin-related modifier SUMO-1

1998 • 415 citations

Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C.

1995 • 410 citations

Cell Cycle–Regulated Attachment of the Ubiquitin-Related Protein Sumo to the Yeast Septins

1999 • 372 citations

Evidence for Covalent Modification of the Nuclear Dot–associated Proteins PML and Sp100 by PIC1/SUMO-1

1997 • 329 citations

Identification of Three Major Sentrinization Sites in PML

1998 • 305 citations

Structural basis for the specificity of ubiquitin C-terminal hydrolases

1999 • 279 citations

The Structure of Papain

1971 • 242 citations

Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 Å resolution

1997 • 229 citations

Characterization of a Fission Yeast SUMO-1 Homologue, Pmt3p, Required for Multiple Nuclear Events, Including the Control of Telomere Length and Chromosome Segregation

1999 • 192 citations

MIPS: a database for genomes and protein sequences

1999 • 164 citations

SUMO-1: wrestling with a new ubiquitin-related modifier

1997 • 143 citations

MIPS: a database for protein sequences and complete genomes

1998 • 135 citations

Crystal structure of the human adenovirus proteinase with its 11 amino acid cofactor.

1996 • 131 citations

There's the Rub: a novel ubiquitin-like modification linked to cell cycle regulation

1998 • 122 citations

X‐ray crystallographic structure of a papain‐leupeptin complex

1993 • 118 citations

Mechanism of ubiquitin carboxyl-terminal hydrolase. Borohydride and hydroxylamine inactivate in the presence of ubiquitin.

1986 • 102 citations

Smt3, a SUMO-1 Homolog, Is Conjugated to Cdc3, a Component of Septin Rings at the Mother-Bud Neck in Budding Yeast

1999 • 101 citations

The Binding Interface between an E2 (UBC9) and a Ubiquitin Homologue (UBL1)

1999 • 95 citations

The Rub Family of Ubiquitin-like Proteins

1998 • 83 citations