Identification of Three Major Sentrinization Sites in PML

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

1997 • 1,221 citations

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex.

1996 • 1,161 citations

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1994 • 798 citations

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1998 • 676 citations

Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells

1994 • 668 citations

Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia.

1993 • 658 citations

The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

1993 • 602 citations

The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer

1997 • 543 citations

The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion.

1994 • 492 citations

Ubc9p Is the Conjugating Enzyme for the Ubiquitin-like Protein Smt3p

1997 • 488 citations

Characterization of NEDD8, a Developmentally Down-regulated Ubiquitin-like Protein

1997 • 484 citations

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

1991 • 464 citations

SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex

1998 • 455 citations

Evidence for a 15; 17 translocation in every patient with acute promyelocytic leukemia

1984 • 441 citations

Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins.

1992 • 441 citations

The RING Finger

1993 • 417 citations

Acute leukemia with promyelocytic features in PML/RARα transgenic mice

1997 • 366 citations

PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia.

1996 • 347 citations

The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition.

1996 • 336 citations

Evidence for Covalent Modification of the Nuclear Dot–associated Proteins PML and Sp100 by PIC1/SUMO-1

1997 • 329 citations

The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML.

1995 • 324 citations

Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin.

1996 • 323 citations

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR.

1993 • 307 citations

PML, a growth suppressor disrupted in acute promyelocytic leukemia.

1994 • 296 citations

Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties.

1991 • 291 citations

Molecular Characterization of the SUMO-1 Modification of RanGAP1 and Its Role in Nuclear Envelope Association

1998 • 290 citations

Identification of a novel nuclear domain.

1991 • 285 citations

Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis.

1990 • 266 citations

Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport.

1995 • 247 citations

UBL1, a Human Ubiquitin-like Protein Associating with Human RAD51/RAD52 Proteins

1996 • 222 citations

Covalent Modification of PML by the Sentrin Family of Ubiquitin-like Proteins

1998 • 208 citations

Preferential Interaction of Sentrin with a Ubiquitin-conjugating Enzyme, Ubc9

1997 • 190 citations

Preferential Modification of Nuclear Proteins by a Novel Ubiquitin-like Molecule

1997 • 173 citations

Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment.

1995 • 154 citations

Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains.

1996 • 133 citations

Analysis of the Growth and Transformation Suppressor Domains of Promyelocytic Leukemia Gene, PML

1996 • 129 citations

Leukemia-associated retinoic acid receptor α fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies

1997 • 123 citations

Identification and Characterization of a Leukocyte-specific Component of the Nuclear Body

1996 • 102 citations

A novel zinc finger protein, Finb, is a transcriptional activator and localized in nuclear bodies

1997 • 19 citations

An antibody reacting with splenic red pulp macrophages in the sera of patients with rheumatic diseases

1991 • 8 citations