Bipolar Disorder and Diabetes Mellitus: Epidemiology, Etiology, and Treatment Implications

Role of Insulin Resistance in Human Disease

1988 • 12,099 citations

Inflamm‐aging: An Evolutionary Perspective on Immunosenescence

2000 • 4,521 citations

Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study

1997 • 4,490 citations

Coordination of circadian timing in mammals

2002 • 4,132 citations

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

2001 • 1,843 citations

Diagnosis and Classification of Diabetes Mellitus

2004 • 1,629 citations

Diabetes and Vascular Disease

2003 • 1,615 citations

The renaissance of GSK3

2001 • 1,459 citations

Glucose Transporters and Insulin Action — Implications for Insulin Resistance and Diabetes Mellitus

1999 • 1,270 citations

Excess Mortality in Bipolar and Unipolar Disorder in Sweden

2001 • 1,107 citations

Is Type II diabetes mellitus a disease of the innate immune system?

1998 • 1,040 citations

Screening for type 2 diabetes.

2000 • 1,030 citations

Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders

2000 • 880 citations

Mortality of patients with mood disorders: follow-up over 34–38 years

2002 • 878 citations

Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins

2003 • 853 citations

Impaired Fasting Glucose Tolerance in First-Episode, Drug-Naive Patients With Schizophrenia

2003 • 834 citations

Cytokine-Induced Sickness Behavior: Where Do We Stand?

2001 • 822 citations

The prevalence and disability of bipolar spectrum disorders in the US population: re-analysis of the ECA database taking into account subthreshold cases

2002 • 751 citations

Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment

2003 • 675 citations

Impaired Glucose Transport as a Cause of Decreased Insulin-Stimulated Muscle Glycogen Synthesis in Type 2 Diabetes

1999 • 666 citations

Are Mood Disorders and Obesity Related? A Review for the Mental Health Professional

2004 • 633 citations

Adipose Tissue IL-6 Content Correlates with Resistance to Insulin Activation of Glucose Uptake both in Vivo and in Vitro

2002 • 577 citations

The neuropsychology and neuroanatomy of bipolar affective disorder: a critical review

2001 • 574 citations

Strange vision: ganglion cells as circadian photoreceptors

2003 • 529 citations

Abnormalities in Glucose Regulation During Antipsychotic Treatment of Schizophrenia

2002 • 519 citations

Two-Year Syndromal and Functional Recovery in 219 Cases of First-Episode Major Affective Disorder With Psychotic Features

2000 • 509 citations

Risk of Recurrence of Bipolar Disorder in Pregnant and Nonpregnant Women After Discontinuing Lithium Maintenance

2000 • 482 citations

Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance.

1998 • 450 citations

Screening for Type 2 Diabetes

2004 • 435 citations

Inflammatory status and insulin resistance

2002 • 420 citations

Inflammatory mediators and islet ?-cell failure: a link between type 1 and type 2 diabetes

2003 • 416 citations

Management of Bipolar Disorder During Pregnancy and the Postpartum Period

2004 • 391 citations

Interleukin-2 and interleukin-6 in schizophrenia and mania: Effects of neuroleptics and mood stabilizers

1995 • 382 citations

Diabetes mellitus in schizophrenic patients

1996 • 380 citations

Diabetes and Vascular Disease

2003 • 372 citations

Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder

2004 • 342 citations

The Inherited Basis of Diabetes Mellitus: Implications for the Genetic Analysis of Complex Traits

2003 • 332 citations

An economic evaluation of manic-depressive illness-1991

1995 • 318 citations

Elevated Frequency of Diabetes Mellitus in Hospitalized Manic-Depressive Patients

1999 • 304 citations

Increased prevalence of type 2 diabetes mellitus among psychiatric inpatients with bipolar I affective and schizoaffective disorders independent of psychotropic drug use

2002 • 294 citations

Psychiatric Illness in Diabetes Mellitus

1986 • 294 citations

Identifying the links between obesity, insulin resistance and β‐cell function: potential role of adipocyte‐derived cytokines in the pathogenesis of type 2 diabetes

2002 • 290 citations

Cognitive Ability and Brain Structure in Type 1 Diabetes

2003 • 276 citations

Loss of circadian rhythm in sleep-wakefulness cycle in the rat by suprachiasmatic nucleus lesions

1975 • 270 citations

Endophenotypes in bipolar disorder†

2002 • 267 citations

Brain Glucose Transporters: Relationship to Local Energy Demand

2001 • 266 citations

Insulin resistance in patients with depression and its changes during the clinical course of depression: Minimal model analysis

2000 • 233 citations

Depression and bipolar disorder: relationships to impaired fatty acid and phospholipid metabolism and to diabetes, cardiovascular disease, immunological abnormalities, cancer, ageing and osteoporosis Possible candidate genes

1999 • 222 citations

The dexamethasone/corticotropin-releasing hormone test in depression in bipolar and unipolar affective illness

1999 • 220 citations

Prevalence of diabetes and impaired glucose tolerance in patients with schizophrenia

2004 • 212 citations

Increased risk of developing dementia in patients with major affective disorders compared to patients with other medical illnesses

2003 • 207 citations

Advancing age and insulin resistance: role of plasma tumor necrosis factor-α

1998 • 205 citations

Prevalence of Overweight and Obesity in Bipolar Patients

2000 • 198 citations

Do Lithium and Anticonvulsants Target the Brain Arachidonic Acid Cascade in Bipolar Disorder?

2002 • 194 citations

Combined dexamethasone/corticotropin-releasing hormone test in acute and remitted manic patients, in acute depression, and in normal controls: I

1995 • 186 citations

Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis

2002 • 183 citations

Mutational spectrum of theWFS1 gene in Wolfram syndrome, nonsyndromic hearing impairment, diabetes mellitus, and psychiatric disease

2003 • 173 citations

Increased risk of developing Parkinson's disease for patients with major affective disorder: a register study

2001 • 164 citations

Insurance Expenditures on Bipolar Disorder: Clinical and Parity Implications

2003 • 162 citations

Cerebral dysfunction in type 1 diabetes: effects of insulin, vascular risk factors and blood-glucose levels

2004 • 153 citations

Neuroimaging in bipolar disorder: what have we learned?

2000 • 153 citations

Glycogen Synthase Kinase-3

2004 • 151 citations

Use of antidepressants in treatment of comorbid diabetes mellitus and depression as well as in diabetic neuropathy.

2001 • 148 citations

High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder

2003 • 143 citations

Cerebral white matter lesions in bipolar affective disorder: relationship to outcome

2001 • 142 citations

Phenotypic and functional characteristics of circulating monocytes of elderly persons☆

1999 • 137 citations

Glycogen Synthase Kinase 3: A Target for Novel Mood Disorder Treatments

2006 • 137 citations

Serious Mental Illness and Tobacco Addiction: A Model Program to Address This Common but Neglected Issue

2003 • 137 citations

DELAYED ACTION OF INSULIN IN SCHIZOPHRENIA

1945 • 132 citations

Clinical Features of Bipolar Disorder with and without Comorbid Diabetes Mellitus

2003 • 128 citations

Studies of hormone action in the hippocampal formation

2002 • 124 citations

Insulin Resistance, Affective Disorders, and Alzheimer's Disease: Review and Hypothesis

2004 • 117 citations

Use of Antidepressants in Treatment of Comorbid Diabetes Mellitus and Depression as Well as in Diabetic Neuropathy

2001 • 117 citations

Immunologic variables in acute mania of bipolar disorder

2004 • 116 citations

Prevalence of diabetes in a manic-depressive population

1980 • 116 citations

Association studies of bipolar disorder

2001 • 116 citations

Mechanisms of antipsychotic-induced weight gain.

2001 • 115 citations

Prevalence of Metabolic Syndrome in Hispanic and Non-Hispanic Patients With Schizophrenia

2004 • 112 citations

Activation of indices of cell-mediated immunity in bipolar mania

1999 • 112 citations

Suicide Attempts in Patients With Bipolar I Disorder During Acute and Maintenance Phases of Intensive Treatment With Pharmacotherapy and Adjunctive Psychotherapy

2002 • 107 citations

HYPERGLYÆMIA IN MENTAL DISORDERS

1919 • 98 citations

Immune dysregulation in major depression: a critical review of existing evidence

2002 • 96 citations

Manic-depression genes and the new millennium: poised for discovery

2002 • 96 citations

Effects of symptomatic severity on elevation of plasma soluble interleukin-2 receptor in bipolar mania

2001 • 94 citations

Non-insulin dependent diabetes mellitus (NIDDM) and patterns of osteoarthritis:The Ulm osteoarthritis study

2001 • 91 citations

Manic-Depressive Illness, Diabetes Mellitus, and Lithium Carbonate

1969 • 89 citations

Glucose-Induced Increase in Memory Performance in Patients With Schizophrenia

1999 • 82 citations

Abnormalities in glucose regulation associated with mental illness and treatment

2002 • 70 citations

Positive and negative acute phase proteins in affective subtypes

1998 • 70 citations

Familial Leukoencephalopathy in Bipolar Disorder

1998 • 62 citations

Tyrosine hydroxylase gene microsatellite polymorphism associated with insulin resistance in depressive disorder

2000 • 62 citations

Electrical Stimulation of the Suprachiasmatic Nucleus of the Hypothalamus Causes Hyperglycemia

1988 • 58 citations

Effect of Acute Psychotic Stress in Nondiabetic Subjects on β-Cell Function and Insulin Sensitivity

2003 • 56 citations

Psychiatric disorders and mutations at the Wolfram syndrome locus

2000 • 54 citations

Additional evidence that the suprachiasmatic nucleus is the center for regulation of insulin secretion and glucose homeostasis

1984 • 46 citations

Peripheral nerve concentrations of glucose, fructose, sorbitol and myoinositol in diabetic and non-diabetic patients

1987 • 46 citations

Serum levels of insulin in overweight patients with osteoarthritis of the knee.

1994 • 36 citations

Increased risk of developing diabetes in depressive and bipolar disorders?

2004 • 33 citations

Elevated sorbitol concentration in the cerebrospinal fluid of patients with mood disorders

2000 • 28 citations

Genetic variations in the WFS1 gene in Japanese with type 2 diabetes and bipolar disorder

2004 • 22 citations

ORAL AND INTRAVENOUS DEXTROSE TOLERANCE CURVES OF PATIENTS WITH MANICDEPRESSIVE PSYCHOSIS

1943 • 16 citations

Deleted Work

1955 • 0 citations