Angiotensin II Receptor Endocytosis Involves Two Distinct Regions of the Cytoplasmic Tail

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

1985 • 1,585 citations

Combining evolutionary information and neural networks to predict protein secondary structure

1994 • 1,471 citations

The Renin-Angiotensin System

1978 • 969 citations

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

1990 • 944 citations

Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway

1993 • 808 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

PHD-an automatic mail server for protein secondary structure prediction

1994 • 561 citations

Protein kinases that phosphorylate activated G protein‐coupled receptors

1995 • 520 citations

Angiotensin II is mitogenic in neonatal rat cardiac fibroblasts.

1993 • 391 citations

Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization.

1993 • 387 citations

A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration.

1994 • 361 citations

The role of clathrin, adaptors and dynamin in endocytosis

1994 • 343 citations

Endocytosis of growth factor receptors

1993 • 277 citations

A general method for introducing a series of mutations into cloned DNA using the polymerase chain reaction

1991 • 253 citations

A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells.

1994 • 253 citations

Dual pathways of internalization of the cholecystokinin receptor.

1995 • 236 citations

Endocytosis and signals for internalization

1991 • 209 citations

Characterization of Sorting Signals in the β-Amyloid Precursor Protein Cytoplasmic Domain

1995 • 194 citations

Morphological and biochemical analysis of angiotensin II internalization in cultured rat aortic smooth muscle cells

1993 • 193 citations

Identification of a cytoplasmic Ser-Thr-Leu motif that determines agonist-induced internalization of the AT1 angiotensin receptor.

1994 • 186 citations

Identification of peptide binding residues in the extracellular domains of the AT1 receptor.

1994 • 168 citations

The mechanism of receptor‐mediated endocytosis

1991 • 164 citations

Correlation of receptor sequestration with sustained diacylglycerol accumulation in angiotensin II-stimulated cultured vascular smooth muscle cells.

1987 • 161 citations

Angiotensin-II-binding sites on hepatocyte nuclei.

1992 • 152 citations

Endocytosis and Lysosomal Targeting of Epidermal Growth Factor Receptors Are Mediated by Distinct Sequences Independent of the Tyrosine Kinase Domain

1995 • 151 citations

Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2.

1994 • 150 citations

Independence of type I angiotensin II receptor endocytosis from G protein coupling and signal transduction.

1994 • 136 citations

The Cytoplasmic Tail of the G-protein-coupled Receptor for Parathyroid Hormone and Parathyroid Hormone-related Protein Contains Positive and Negative Signals for Endocytosis

1995 • 133 citations

Agonist-stimulated internalization of the thyrotropin-releasing hormone receptor is dependent on two domains in the receptor carboxyl terminus.

1993 • 132 citations

Role of receptor cycling in the regulation of angiotensin II surface receptor number and angiotensin II uptake in rat vascular smooth muscle cells.

1989 • 131 citations

Stable Expression of a Truncated AT1A Receptor in CHO-K1 Cells

1995 • 129 citations

Identification of a novel sequence mediating regulated endocytosis of the G protein-coupled alpha-pheromone receptor in yeast.

1993 • 126 citations

Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain.

1990 • 121 citations

Stoichiometric Interaction of the Epidermal Growth Factor Receptor with the Clathrin-associated Protein Complex AP-2

1995 • 119 citations

Serines and threonines in the gastrin-releasing peptide receptor carboxyl terminus mediate internalization.

1993 • 105 citations

Association of Epidermal Growth Factor Receptors with Coated Pit Adaptins via a Tyrosine Phosphorylation-regulated Mechanism

1995 • 98 citations

A proline-rich region of the third intracellular loop imparts phenotypic beta 1-versus beta 2-adrenergic receptor coupling and sequestration

1994 • 98 citations

Internalization of the rat AT_1a and AT_1b receptors: pharmacological and functional requirements

1994 • 95 citations

Processing of Angiotensin II (A-II) and (Sar¹Ala⁸)A-II by Cultured Bovine Adrenocortical Cells*

1986 • 95 citations

Transplanted LDL and mannose-6-phosphate receptor internalization signals promote high-efficiency endocytosis of the transferrin receptor.

1991 • 93 citations

Involvement of dileucine motifs in the internalization and degradation of the insulin receptor

1994 • 90 citations

Clathrin, Adapters, And Sorting

1990 • 89 citations

Clathrin: Its Role in Receptor-Mediated Vesicular Transport and Specialized Functions in Neurons

1993 • 84 citations

Agonist-induced endocytosis and signal generation in adrenal glomerulosa cells. A potential mechanism for receptor-operated calcium entry.

1991 • 80 citations

The conserved NPXnY motif present in the gastrin-releasing peptide receptor is not a general sequestration sequence.

1994 • 73 citations

Structural analysis and regulation of angiotensin II receptors

1994 • 71 citations

The structure of an endocytosis signal

1992 • 56 citations

Molecular cloning of porcine soluble angiotensin-binding protein.

1992 • 53 citations

How to estimate the total receptor concentration when the specific radioactivity of the ligand is unknown

1992 • 48 citations

Stable expression of a functional rat angiotensin II (AT1A) receptor in CHO-K1 cells: Rapid desensitization by angiotensin II

1995 • 45 citations

The tyrosine-containing internalization motif in the cytoplasmic domain of TGN38/41 lies within a nascent helix.

1994 • 35 citations

Carboxyl-terminal Domains in the Avian β1-Adrenergic Receptor That Regulate Agonist-promoted Endocytosis

1995 • 31 citations

Divergent conformational requirements for angiotensin II receptor internalization and signaling

1994 • 20 citations