Saccharomyces cerevisiae DNA repair processes: an update

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

The double-strand-break repair model for recombination

1983 • 2,468 citations

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1993 • 2,282 citations

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

1994 • 2,071 citations

Mutation of a mutL Homolog in Hereditary Colon Cancer

1994 • 1,834 citations

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

1994 • 1,544 citations

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

1992 • 1,231 citations

DMC1: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression

1992 • 1,133 citations

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

1993 • 1,076 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

Catalysis of ATP-Dependent Homologous DNA Pairing and Strand Exchange by Yeast RAD51 Protein

1994 • 843 citations

Proliferating cell nuclear antigen is required for DNA excision repair

1992 • 809 citations

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

1995 • 785 citations

A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae

1990 • 683 citations

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 • 599 citations

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

1990 • 591 citations

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

1995 • 536 citations

Absence of p350 Subunit of DNA-Activated Protein Kinase from a Radiosensitive Human Cell Line

1995 • 530 citations

GTBP, a 160-Kilodalton Protein Essential for Mismatch-binding Activity in Human Cells

1995 • 528 citations

Mutations of GTBP in Genetically Unstable Cells

1995 • 471 citations

Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.

1994 • 394 citations

MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair.

1995 • 391 citations

Characterization of Double-Strand Break-Induced Recombination: Homology Requirements and Single-Stranded DNA Formation

1992 • 377 citations

Removal of Nonhomologous DNA Ends in Double-Strand Break Recombination: the Role of the Yeast Ultraviolet Repair Gene RAD1

1992 • 375 citations

Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction

1994 • 371 citations

Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions.

1992 • 353 citations

Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated.

1992 • 345 citations

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

1993 • 317 citations

Mismatch repair: mechanisms and relationship to cancer susceptibility

1995 • 307 citations

Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins.

1995 • 297 citations

MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in Yeast

1994 • 287 citations

REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase

1989 • 270 citations

Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae.

1995 • 269 citations

DNA double-strand breaks and the RAD50-RAD57 genes in Saccharomyces.

1993 • 249 citations

RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.

1994 • 246 citations

Mutations in XRS2 and RAD50 Delay but Do Not Prevent Mating-Type Switching in Saccharomyces cerevisiae

1994 • 232 citations

Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52.

1993 • 228 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.

1994 • 222 citations

Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins.

1992 • 221 citations

EFFECTS OF THE RAD52 GENE ON RECOMBINATION IN SACCHAROMYCES CEREVISIAE

1980 • 220 citations

Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations.

1995 • 219 citations

RAD1 and RAD10, but Not Other Excision Repair Genes, Are Required for Double-Strand Break-Induced Recombination in Saccharomyces cerevisiae

1995 • 217 citations

Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation.

1991 • 211 citations

A Role for Exonuclease I from S. pombe in Mutation Avoidance and Mismatch Correction

1995 • 202 citations

Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae.

1995 • 201 citations

The RAD7 and RAD16 genes, which are essential for pyrimidine dimer removal from the silent mating type loci, are also required for repair of the nontranscribed strand of an active gene in Saccharomyces cerevisiae.

1994 • 200 citations

Yeast DNA repair and recombination proteins Rad1 and Rad1O constitute a single-stranded-DNA endonuclease

1993 • 198 citations

GENETIC CONTROL OF RADIATION SENSITIVITY IN SACCHAROMYCES CEREVISIAE

1969 • 191 citations

A unique pathway of double-strand break repair operates in tandemly repeated genes.

1991 • 179 citations

DNA Repair Protein XPA Binds Replication Protein A (RPA)

1995 • 176 citations

Factors that affect the location and frequency of meiosis-induced double-strand breaks in Saccharomyces cerevisiae.

1995 • 176 citations

Co-correction of the ERCC1, ERCC4 and xeroderma pigmentosum group F DNA repair defects in vitro.

1993 • 171 citations

Binding of Mismatched Microsatellite DNA Sequences by the Human MSH2 Protein

1994 • 166 citations

Heteroduplex DNA correction in Saccharomyces cerevisiae is mismatch specific and requires functional PMS genes.

1989 • 164 citations

Purification and characterization of the SRS2 DNA helicase of the yeast Saccharomyces cerevisiae.

1993 • 160 citations

Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.

1995 • 147 citations

Yeast excision repair gene RAD2 encodes a single-stranded DNA endonuclease

1993 • 143 citations

Multiple pathways for homologous recombination in Saccharomyces cerevisiae.

1995 • 142 citations

Role of the Rad1 and Rad10 Proteins in Nucleotide Excision Repair and Recombination

1995 • 134 citations

Suppression of a new allele of the yeast RAD52 gene by overexpression of RAD51, mutations in srs2 and ccr4, or mating-type heterozygosity.

1995 • 133 citations

RAD50 protein ofS.cerevisiaeexhibits ATP-dependent DNA binding

1993 • 124 citations

Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli.

1989 • 124 citations

A Novel Allele of Saccharomyces cerevisiae RFA1 That Is Deficient in Recombination and Repair and Suppressible by RAD52

1995 • 124 citations

Two Alternative Pathways of Double-Strand Break Repair That Are Kinetically Separable and Independently Modulated

1992 • 121 citations

RecA-like Recombination Proteins in Eukaryotes: Functions and Structures of RAD51 Genes

1993 • 118 citations

A Mutation in the Gene Encoding the Saccharomyces cerevisiae Single-Stranded DNA-Binding Protein Rfa1 Stimulates a RAD52-Independent Pathway for Direct-Repeat Recombination

1995 • 116 citations

Homotypic and heterotypic protein associations control Rad51 function in double-strand break repair.

1994 • 111 citations

Sequence of the RAD55 gene of Saccharomyces cerevisiae: similarity of RAD55 to prokaryotic RecA and other RecA-like proteins

1994 • 108 citations

Molecular cloning of RAD16, a gene involved in differential repair inSaccharomyces cerevisiae

1992 • 108 citations

Nucleotide sequence of the RAD57 gene of Saccharomyces cerevisiae

1991 • 107 citations

The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions.

1995 • 106 citations

Mitotic chromosome loss in a radiation-sensitive strain of the yeast Saccharomyces cerevisiae.

1981 • 105 citations

DNA Polymerases Required for Repair of UV-Induced Damage in Saccharomyces cerevisiae

1995 • 101 citations

Yeast DNA-repair gene RAD14 encodes a zinc metalloprotein with affinity for ultraviolet-damaged DNA.

1993 • 98 citations

Stable and specific association between the yeast recombination and DNA repair proteins RAD1 and RAD10 in vitro.

1992 • 92 citations

CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter context.

1994 • 88 citations

Yeast DNA Repair Protein RAD23 Promotes Complex Formation between Transcription Factor TFIIH and DNA Damage Recognition Factor RAD14

1995 • 83 citations

A Unique Pathway of Double-Strand Break Repair Operates in Tandemly Repeated Genes

1991 • 80 citations

Differential repair of UV damage in rad mutants of Saccharomyces cerevisiae: a possible function of G2 arrest upon UV irradiation.

1990 • 70 citations

The effect of DNA mismatches on the ATPase activity of MSH1, a protein in yeast mitochondria that recognizes DNA mismatches.

1994 • 69 citations

Isolation and characterization of yeast DNA repair genes

1983 • 67 citations

Use of a selection technique to identify the diversity of binding sites for the yeast RAP1 transcription factor

1994 • 63 citations

Modulation of Saccharomyces cerevisiae DNA double-strand break repair by SRS2 and RAD51.

1995 • 59 citations

Removal of pyrimidine dimers from saccharomyces cerevisiae nuclear DNA under nongrowth conditions as detected by a sensitive, enzymatic assay

1978 • 57 citations

Heteroduplex DNA Correction in Saccharomyces cerevisiae Is Mismatch Specific and Requires Functional PMS Genes

1989 • 56 citations

The RAD7 and RAD16 Genes, Which Are Essential for Pyrimidine Dimer Removal from the Silent Mating Type Loci, Are Also Required for Repair of the Nontranscribed Strand of an Active Gene in Saccharomyces cerevisiae

1994 • 56 citations

Purification and characterization of an endo-exonuclease from Saccharomyces cerevisiae that is influenced by the RAD52 gene.

1987 • 55 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene

1994 • 54 citations

Interaction of the yeast RAD7 and SIR3 proteins: implications for DNA repair and chromatin structure.

1994 • 51 citations

Cellular Role of Yeast Apnl Apurinic Endonuclease/3′-Diesterase: Repair of Oxidative and Alkylation DNA Damage and Control of Spontaneous Mutation

1991 • 49 citations

Regulated expression of theSaccharomyces cerevisiaeDNA repair gene RAD7 in response to DNA damage and during sporulation

1990 • 43 citations

Two DNA Repair and Recombination Genes in Saccharomyces cerevisiae, RAD52 and RAD54, Are Induced during Meiosis

1989 • 38 citations

Negative superhelicity promotes ATP-dependent binding of yeast RAD3 protein to ultraviolet-damaged DNA.

1994 • 36 citations

Characterization of a DNA mismatch-binding activity in yeast extracts.

1993 • 34 citations

CCR4 Is a Glucose-Regulated Transcription Factor Whose Leucine-Rich Repeat Binds Several Proteins Important for Placing CCR4 in Its Proper Promoter Context

1994 • 33 citations

Postreplication repair in Saccharomyces cerevisiae

1981 • 28 citations

Stable and Specific Association between the Yeast Recombination and DNA Repair Proteins RAD1 and RADIO In Vitro

1992 • 26 citations

Mutations in the Saccharomyces cerevisiae CDC1 gene affect double-strand-break-induced intrachromosomal recombination.

1994 • 20 citations

Differential Repair of UV Damage in rad Mutants of Saccharomyces cerevisiae: a Possible Function of G₂ Arrest upon UV Irradiation

1990 • 17 citations

Mutations in the Saccharomyces cerevisiae CDC1 Gene Affect Double-Strand-Break-Induced Intrachromosomal Recombination

1994 • 8 citations

Recent Insights on DNA Repair: The Mechanism of Damaged Nucleotide Excision in Eukaryotes and Its Relationship to Other Cellular Processes^a

1994 • 6 citations