Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Experiments in molecular genetics

1972 • 28,260 citations

Methods in yeast genetics

1979 • 7,824 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

1988 • 1,734 citations

Chemical and biological evolution of a nucleotide-binding protein

1974 • 1,457 citations

The molecular biology of the yeast saccharomyces: Life cycle and inheritance

1982 • 1,361 citations

Visualization of nucleolar organizer regions in mammalian chromosomes using silver staining

1975 • 1,131 citations

A Method for Gene Disruption That Allows Repeated Use of URA3 Selection in the Construction of Multiply Disrupted Yeast Strains

1987 • 887 citations

Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces.

1984 • 827 citations

THE GENETIC CONTROL OF MEIOSIS

1976 • 653 citations

THE SYNAPTONEMAL COMPLEX IN GENETIC SEGREGATION

1984 • 585 citations

ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins.

1986 • 538 citations

Double-strand breaks at an initiation site for meiotic gene conversion

1989 • 533 citations

A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase

1989 • 532 citations

Carbohydrate Metabolism During Ascospore Development in Yeast

1974 • 425 citations

Genetic recombination

1989 • 373 citations

A rapid, efficient method for isolating DNA from yeast

1986 • 358 citations

α-Helical coiled coils — a widespread motif in proteins

1986 • 350 citations

Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes

1980 • 345 citations

SYNAPTINEMAL COMPLEX

1968 • 323 citations

Cytology of the Yeast Life Cycle

1981 • 295 citations

Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II

1988 • 293 citations

A General Method for Saturation Mutagenesis of Cloned DNA Fragments

1985 • 292 citations

SPINDLES, SPINDLE PLAQUES, AND MEIOSIS IN THE YEAST SACCHAROMYCES CEREVISIAE (HANSEN)

1971 • 278 citations

Mutation of lysine-48 to arginine in the yeast RAD3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP.

1988 • 263 citations

Three-dimensional structure of adenyl kinase

1974 • 258 citations

THE ROLE OF RADIATION (rad) GENES IN MEIOTIC RECOMBINATION IN YEAST

1980 • 257 citations

Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold

1988 • 251 citations

HOP1: a yeast meiotic pairing gene.

1989 • 250 citations

DNA Repair and Mutagenesis in Yeast

1981 • 242 citations

Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit β-globin

1980 • 227 citations

THE ROLE OF THE SPO11 GENE IN MEIOTIC RECOMBINATION IN YEAST

1985 • 226 citations

Molecular Genetics of Yeast

1980 • 223 citations

EVIDENCE FOR TWO TYPES OF ALLELIC RECOMBINATION IN YEAST

1963 • 203 citations

Gene conversion, recombination nodules, and the initiation of meiotic synapsis

1987 • 203 citations

SYNAPTONEMAL COMPLEX AND RECOMBINATION NODULES IN WILD-TYPE DROSOPHILA MELANOGASTER FEMALES

1979 • 189 citations

Construction and genetic characterization of temperature-sensitive mutant alleles of the yeast actin gene.

1984 • 177 citations

Development of the synaptonemal complex and the ?recombination nodules? during meiotic prophase in the seven bivalents of the fungus Sordaria macrospora Auersw

1977 • 177 citations

The meiotic prophase in Bombyx mori females analyzed by three-dimensional reconstructions of synaptonemal complexes

1976 • 171 citations

RECOMBINATION AND CHROMOSOME SEGREGATION DURING THE SINGLE DIVISION MEIOSIS IN SPO12–1 AND SPO13–1 DIPLOIDS

1980 • 170 citations

Electron microscopic observations on the meiotic karyotype of diploid and tetraploid Saccharomyces cerevisiae.

1975 • 167 citations

Recombination nodules and synaptonemal complex in recombination-defective females of Drosophila melanogaster

1979 • 167 citations

Meiotic chromosome behavior in spread preparations of yeast.

1988 • 162 citations

Synaptonemal complex spreading in Allium cepa and A. fistulosum

1987 • 162 citations

Molecular Mechanisms of Chromosome Pairing, Folding and Function

1971 • 142 citations

The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions.

1989 • 139 citations

Regulation of RAD54- and RAD52-lacZ gene fusions in Saccharomyces cerevisiae in response to DNA damage.

1987 • 137 citations

Genetic Recombination and Commitment to Meiosis in Saccharomyces

1974 • 135 citations

Recombinationless meiosis in Saccharomyces cerevisiae.

1981 • 132 citations

MEIOTIC GENE CONVERSION IN YEAST TETRADS AND THE THEORY OF RECOMBINATION

1967 • 132 citations

MER1, a Yeast Gene Required for Chromosome Pairing and Genetic Recombination, Is Induced in Meiosis

1990 • 124 citations

The synaptonemal complex and the spindle plaque during meiosis in yeast

1975 • 115 citations

Mutations in the nucleotide binding loop of adenylate kinase of Escherichia coli

1988 • 114 citations

Gene conversions and their relation to homologous chromosome pairing

1986 • 112 citations

Genetic control of chromosome synapsis in yeast meiosis

1989 • 106 citations

Glu-111 is required for activation of the DNA cleavage center of EcoRI endonuclease

1989 • 104 citations

Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens.

1987 • 104 citations

THE TIME AND PLACE OF MEIOTIC CROSSING-OVER

1970 • 104 citations

Recombination and meiosis

1977 • 101 citations

Quantitative Electron Microscopy of Chromosome Organization at Meiotic Prophase

1974 • 92 citations

Directed mutagenesis of the beta-subunit of F1-ATPase from Escherichia coli.

1987 • 90 citations

Multiple mutant analysis of recombination in yeast

1983 • 82 citations

Human meiosis VIII. Chromosome pairing and formation of the synaptonemal complex in oocytes

1983 • 80 citations

The Synaptonemal Complex in Genetic Segregation

1984 • 78 citations

PREFERENTIAL OCCURRENCE OF NONSISTER SPORES IN TWO-SPORED ASCI OF SACCHAROMYCES CEREVISIAE: EVIDENCE FOR REGULATION OF SPORE-WALL FORMATION BY THE SPINDLE POLE BODY

1980 • 77 citations

MER1, a yeast gene required for chromosome pairing and genetic recombination, is induced in meiosis.

1990 • 70 citations

Investigating the Genetic Control of Biochemical Events in Meiotic Recombination

1987 • 62 citations

Synaptonemal complex formation in pollen mother cells of Tradescantia

1984 • 56 citations

Morphogenesis of the synapton during yeast meiosis

1979 • 43 citations

Meiotic Exchange within and between Chromosomes Requires a Common Rec Function in Saccharomyces cerevisiae

1985 • 43 citations

Meiotic prophase in anthers of asynaptic wheat

1970 • 42 citations

A sequential analysis of the development of the synaptonemal complex in spermatocytes of the mouse by electron microscopy using hydroxyurea and agar filtration

1983 • 35 citations

Diversity among β-Tubulins: A Carboxy-Terminal Domain of Yeast β-Tubulin Is Not Essential In Vivo

1988 • 32 citations

Light and electron microscope observations of a meiotic mutant of Neurospora crassa

1978 • 32 citations

MEIOTIC DNA METABOLISM IN WILD-TYPE AND EXCISION-DEFICIENT YEAST FOLLOWING UV EXPOSURE

1983 • 30 citations

Meiotic exchange within and between chromosomes requires a common Rec function in Saccharomyces cerevisiae.

1985 • 21 citations

Synaptonemal complexes of normal and mutant yeast chromosomes (Saccharomyces cerevisiae)

1985 • 19 citations

Diversity among beta-tubulins: a carboxy-terminal domain of yeast beta-tubulin is not essential in vivo.

1988 • 16 citations

Extragenic revertants of rad50, a yeast mutation causing defects in recombination and repair

1985 • 14 citations

Synchronous sporulation in spheroplasts of yeast, Saccharomyces cerevisiae.

1981 • 7 citations

A new twist to the topoisomerase I problem

1989 • 7 citations

Isolation and characterization of yeast mutants defective in meiotic chromosome segregation.

1989 • 4 citations