Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Biostatistical Analysis.

1975 • 10,200 citations

Genomic sequencing.

1984 • 8,343 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

1943 • 3,852 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

The double-strand-break repair model for recombination

1983 • 2,468 citations

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

1986 • 1,525 citations

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

1993 • 1,076 citations

Guide to yeast genetics and molecular biology

1992 • 1,032 citations

Replacement of chromosome segments with altered DNA sequences constructed in vitro.

1979 • 779 citations

The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants

1989 • 728 citations

[20] In vitro mutagenesis and plasmid shuffling: From cloned gene to mutant yeast

1991 • 584 citations

DNA Mismatch Correction in a Defined System

1989 • 551 citations

Genetic analysis of yeast RAS1 and RAS2 genes

1984 • 460 citations

DNA MISMATCH CORRECTION

1987 • 427 citations

Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions.

1992 • 353 citations

Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs.

1986 • 353 citations

Nuclear location signals in polyoma virus large-T

1986 • 351 citations

Mispair specificity of methyl-directed DNA mismatch correction in vitro.

1988 • 341 citations

Initiation of methyl-directed mismatch repair.

1992 • 313 citations

MKK1 and MKK2, Which Encode Saccharomyces cerevisiae Mitogen-Activated Protein Kinase-Kinase Homologs, Function in the Pathway Mediated by Protein Kinase C

1993 • 306 citations

Isolation and Characterization of the Escherichia coli mutL Gene Product

1989 • 298 citations

Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins.

1992 • 221 citations

Isolation and characterization of the Escherichia coli mutH gene product.

1987 • 220 citations

MEIOTIC GENE CONVERSION MUTANTS IN SACCHAROMYCES CEREVISIAE. I. ISOLATION AND CHARACTERIZATION OF pms1-1 AND pms1-2

1985 • 220 citations

Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB

1989 • 193 citations

5-Methylcytosine is not detectable in Saccharomyces cerevisiae DNA.

1984 • 175 citations

Cloning of yeast TOP1, the gene encoding DNA topoisomerase I, and construction of mutants defective in both DNA topoisomerase I and DNA topoisomerase II.

1985 • 168 citations

Heteroduplex DNA correction in Saccharomyces cerevisiae is mismatch specific and requires functional PMS genes.

1989 • 164 citations

Molecular Matchmakers

1993 • 153 citations

Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene

1989 • 148 citations

The yeast gene MSH3 defines a new class of eukaryotic MutS homologues

1993 • 140 citations

Use of the DNA polymerase chain reaction for homology probing: isolation of partial cDNA or genomic clones encoding the iron-sulfur protein of succinate dehydrogenase from several species.

1989 • 136 citations

Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene.

1989 • 128 citations

A defect in mismatch repair in Saccharomyces cerevisiae stimulates ectopic recombination between homeologous genes by an excision repair dependent process.

1990 • 117 citations

Histone H2B subtypes are dispensable during the yeast cell cycle

1981 • 104 citations

Specificity of mismatch repair following transformation of Saccharomyces cerevisiae with heteroduplex plasmid DNA.

1989 • 98 citations

The E. coli uvrD gene product is DNA helicase II

1983 • 88 citations

The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiae

1987 • 86 citations

Nucleotide sequence of the Salmonella typhimurium mutS gene required for mismatch repair: homology of MutS and HexA of Streptococcus pneumoniae

1988 • 83 citations

Mechanisms of DNA-mismatch correction

1990 • 81 citations

Nucleotide sequence of the hexA gene for DNA mismatch repair in Streptococcus pneumoniae and homology of hexA to mutS of Escherichia coli and Salmonella typhimurium

1988 • 75 citations

Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae.

1991 • 71 citations

Isolation and characterization of yeast DNA repair genes

1983 • 67 citations

Nucleotide sequence of the Streptococcus pneumoniae hexB mismatch repair gene: homology of HexB to MutL of Salmonella typhimurium and to PMS1 of Saccharomyces cerevisiae

1989 • 61 citations

Genetic recombination

1996 • 55 citations

Histone H2A subtypes associate interchangeably in vivo with histone H2B subtypes.

1982 • 54 citations

Theswi4⁺gene ofSchizosaccharomyces pombeencodes a homologue of mismatch repair enzymes

1992 • 52 citations

Nucleotide sequence of the Salmonella typhimurium mutL gene required for mismatch repair: homology of MutL to HexB of Streptococcus pneumoniae and to PMS1 of the yeast Saccharomyces cerevisiae

1989 • 42 citations

Recombinational repair of diverged DNAs : a study of homoeologous chromosomes and mammalian YACs in yeast

1992 • 36 citations

Characterization of a DNA mismatch-binding activity in yeast extracts.

1993 • 34 citations

Meiotic mismatch repair quantified on the basis of segregation patterns in Schizosaccharomyces pombe.

1993 • 32 citations

DNA Mismatch Correction

1987 • 19 citations

Analysis of gene expression using episomal mouse dihydrofolate reductase minigenes

1988 • 18 citations

The sequence of a 6·3 kb segment of yeast chromosome III reveals an open reading frame coding for a putative mismatch binding protein

1991 • 9 citations

Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae.

1991 • 4 citations