Restricted inflammatory reaction in the CNS: a key impediment to axonal regeneration?

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

1981 • 1,679 citations

Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors

1990 • 1,232 citations

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

1991 • 1,171 citations

T‐lymphocyte entry into the central nervous system

1991 • 1,168 citations

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats

1998 • 794 citations

Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide.

1993 • 782 citations

Spinal Cord Repair in Adult Paraplegic Rats: Partial Restoration of Hind Limb Function

1996 • 764 citations

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages.

1987 • 711 citations

The macrophage response to central and peripheral nerve injury. A possible role for macrophages in regeneration.

1987 • 596 citations

The Pathobiology of Traumatically Induced Axonal Injury in Animals and Humans: A Review of Current Thoughts

1995 • 492 citations

Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin.

1991 • 455 citations

Macrophages and the Nervous System

1991 • 429 citations

Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors

1985 • 415 citations

Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord.

1997 • 375 citations

The role of non-resident cells in Wallerian degeneration

1984 • 350 citations

The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats

1994 • 330 citations

Degeneration & regeneration of the nervous system

1928 • 306 citations

Delayed Macrophage Responses and Myelin Clearance during Wallerian Degeneration in the Central Nervous System: The Dorsal Radiculotomy Model

1994 • 303 citations

Transplantation of activated macrophages overcomes central nervous system regrowth failure

1996 • 281 citations

Opioid and Opiate Immunoregulatory Processes

1996 • 277 citations

Activated Macrophage/Microglial Cells Can Promote the Regeneration of Sensory Axons into the Injured Spinal Cord

1997 • 268 citations

Grafting of cultured microglial cells into the lesioned spinal cord of adult rats enhances neurite outgrowth

1997 • 251 citations

Macrophage function during Wallerian degeneration of rat optic nerve: clearance of degenerating myelin and Ia expression

1989 • 228 citations

Inflammation in the nervous system

1995 • 223 citations

Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments

1993 • 216 citations

Macrophages and inflammatory damage in spinal cord injury.

1992 • 211 citations

Lipoprotein Uptake by Neuronal Growth Cones in Vitro

1987 • 209 citations

Macrophage-mediated myelin-related mitogenic factor for cultured Schwann cells.

1988 • 157 citations

Cross talk between the immune system and the nervous system in response to injury: implications for regeneration

1994 • 149 citations

Brain macrophages stimulate neurite growth and regeneration by secreting thrombospondin

1994 • 148 citations

Involvement of wound-associated factors in rat brain astrocyte migratory response to axonal injury: in vitro simulation.

1996 • 143 citations

Inflammation after axonal injury has conflicting consequences for recovery of function: Rescue of spared axons is impaired but regeneration is supported

1994 • 137 citations

Schwann cells degrade myelin and proliferate in the absence of macrophages: evidence fromin vitro studies of Wallerian degeneration

1995 • 133 citations

Macrophage-Derived Growth Factors

1992 • 131 citations

Adult Rat Dorsal Root Ganglion Neurons Extend Neurites on Predegenerated But Not on Normal Peripheral Nerves In Vitro

1992 • 130 citations

Immunoregulatory role of neurotransmitters

1996 • 117 citations

Laminin overrides the inhibitory effects of peripheral nervous system and central nervous system myelin‐derived inhibitors of neurite growth

1995 • 114 citations

Recovery of Visual Response of Injured Adult Rat Optic Nerves Treated with Transglutaminase

1994 • 110 citations

Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery.

1995 • 102 citations

Macrophage recruitment to acutely injured central nervous system is inhibited by a resident factor: a basis for an immune-brain barrier

1995 • 89 citations

Differential effects of central and peripheral nerves on macrophages and microglia

1998 • 77 citations

The Critical Period for Repair of CNS of Neonatal Opossum (Monodelphis domestica) in Culture: Correlation with Development of Glial Cells, Myelin and Growth‐inhibitory Molecules

1995 • 65 citations

Delayed wallerian degeneration in the central nervous system of Ola mice: an ultrastructural study

1992 • 59 citations

Axonal regeneration is associated with glial migration: Comparison between the injured optic nerves of fish and rats

1993 • 54 citations

Dichotomy of the glial cell response to axonal injury and regeneration

1989 • 45 citations

Lymphocytes and macrophages outnumber oligodendroglia in normal fish spinal cord.

1993 • 41 citations

Vitronectin overrides a negative effect of TNF-alpha on astrocyte migration.

1995 • 39 citations

The enigma of myelin-associated growth inhibitors in spontaneously regenerating nervous systems

1994 • 39 citations

Chapter 20 Permissive and restrictive periods for brainstem-spinal regeneration in the chick

1994 • 31 citations

Quantitative Effects of Peripheral Monocytes and Nerve Growth Factor on CNS Neural Morphometric Outgrowth Parametersin Vitro

1996 • 18 citations

Transplantaion of embryonic chick spinal cord into transection adult chicken into transection adult chicken spinal cords: A useful model for transplantation research

1985 • 8 citations