Inflammation in the nervous system

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1995 • 2,456 citations

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1990 • 1,763 citations

Molecular profile of reactive astrocytes—Implications for their role in neurologic disease

1993 • 1,436 citations

Clinical trial of indomethacin in Alzheimer's disease

1993 • 996 citations

Cytokines and the nervous system II: actions and mechanisms of action

1995 • 928 citations

Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

1985 • 881 citations

Cytokines and the nervous system I: expression and recognition

1995 • 745 citations

Microglia in degenerative neurological disease

1993 • 594 citations

Inverse association of anti‐inflammatory treatments and Alzheimer's disease

1994 • 567 citations

Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat

1992 • 547 citations

Secondary Cell Death and the Inflammatory Reaction After Dorsal Hemisection of the Rat Spinal Cord

1994 • 531 citations

Macrophages and the Nervous System

1991 • 429 citations

Anti‐inflammatory agents as a therapeutic approach to Alzheimer's disease

1992 • 396 citations

Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system.

1990 • 388 citations

Postischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in rats.

1994 • 347 citations

The acute inflammatory response to lipopolysaccharide in cns parenchyma differs from that in other body tissues

1992 • 322 citations

Cytokines and the nervous system I: expression and recognition

1995 • 307 citations

Neutrophil Accumulation After Traumatic Brain Injury in Rats: Comparison of Weight Drop and Controlled Cortical Impact Models

1994 • 285 citations

The neuropathogenesis of HIV-1 infection

1994 • 277 citations

Neonatal endotoxin exposure alters the development of the hypothalamic- pituitary-adrenal axis: early illness and later responsivity to stress

1995 • 275 citations

The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration

1991 • 252 citations

Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages

1990 • 230 citations

Regional induction of tumor necrosis factor alpha expression in the mouse brain after systemic lipopolysaccharide administration.

1994 • 228 citations

Glial changes following an excitotoxic lesion in the CNS—I. Microglia/macrophages

1991 • 215 citations

The Mac-1 and p150,95 β2 integrins bind denatured proteins to mediate leukocyte cell-substrate adhesion

1992 • 214 citations

Reduction of central nervous system ischemic injury by monoclonal antibody to intercellular adhesion molecule

1991 • 207 citations

Endotoxin-induced appearance of immunoreactive interleukin-1β in ramified microglia in rat brain: A light and electron microscopic study

1995 • 193 citations

Antigen Markers of Macrophage Differentiation in Murine Tissues

1992 • 193 citations

Extracellular ATP activates a cation conductance and a K+ conductance in cultured microglial cells from mouse brain

1993 • 173 citations

Upregulation and coexpression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system.

1990 • 173 citations

Inhibition of Posttraumatic Microglial Proliferation in a Genetic Model of Macrophage Colony‐Stimulating Factor Deficiency in the Mouse

1994 • 170 citations

Heterogeneity of microglial and perivascular cell populations: Insights gained from the facial nucleus paradigm

1993 • 162 citations

Microglial Reaction in the Rat Cerebral Cortex Induced by Cortical Spreading Depression

1993 • 156 citations

Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system.

1992 • 156 citations

Characterization of the microglial response in murine scrapie

1994 • 144 citations

Blood monocytes and spleen macrophages differentiate into microglia‐like cells on monolayers of astrocytes: Morphology

1994 • 141 citations

Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis

1994 • 133 citations

Radiation‐induced Reductions in Macrophage Recruitment Have Only Slight Effects on Myelin Degeneration in Sectioned Peripheral Nerves of Mice

1995 • 117 citations

Cell adhesion molecules on vessels during inflammation in the mouse central nervous system

1994 • 105 citations

Demyelination in the central nervous system following a delayed-type hypersensitivity response to bacillus Calmette-Guérin

1995 • 104 citations

The blood-brain barrier regulates the expression of a macrophage sialic acid-binding receptor on microglia

1992 • 93 citations

Quantification of the mononuclear phagocyte response to Wallerian degeneration of the optic nerve

1994 • 86 citations

Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: Membrane currents

1994 • 85 citations

Mitosis and apoptosis of microgliain vivo induced by an anti-CR3 antibody which crosses the blood-brain barrier

1993 • 78 citations

Cytokine-dependent K+ channel profile of microglia at immunologically defined functional states

1995 • 75 citations

Developmental changes in the sensitivity of the neonatal rat brain to hypoxic/ischemic injury

1994 • 71 citations

Activated T cells of nonneural specificity open the blood‐nerve barrier to circulating antibody

1995 • 70 citations

Adhesion molecule expression on murine cerebral endothelium following the injection of a proinflammagen or during acute neuronal degeneration

1995 • 69 citations

The Unique Characteristics of Inflammatory Responses in Mouse Brain are Acquired During Postnatal Development

1995 • 64 citations

Lipopolysaccharide intracerebral administration induces minimal inflammatory reaction in rat brain

1994 • 53 citations

Tetanus toxin-induced seizures cause microglial activation in rat hippocampus

1990 • 47 citations

Physiological role, molecular structure and evolutionary relationships of voltage-gated potassium channels in T lymphocytes

1993 • 30 citations